Ming Wei
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View article: Genomic diversity, antimicrobial resistance and dissemination of Serratia marcescens complex in patients admitted to ICUs
Genomic diversity, antimicrobial resistance and dissemination of Serratia marcescens complex in patients admitted to ICUs Open
Background Serratia spp. is an important nosocomial pathogen, with increasing threat of antimicrobial resistance. We aimed to describe the population structure, antimicrobial resistance and dissemination of Serratia isolates in ICUs of Chi…
View article: Genomic epidemiology and antimicrobial resistance of Morganella clinical isolates between 2016 and 2023
Genomic epidemiology and antimicrobial resistance of Morganella clinical isolates between 2016 and 2023 Open
Morganella morganii is a Gram-negative, opportunistic pathogen that is often associated with nosocomial infections. Here, the genomic characteristics and antimicrobial resistance (AMR) of Morganella clinical isolates between 2016 and 2023 …
View article: Genomic evolution, antimicrobial resistance, and dissemination of global Serratia spp. unveil increasing species diversity and carbapenemae‑resistance: A retrospective and genomic epidemiology study
Genomic evolution, antimicrobial resistance, and dissemination of global Serratia spp. unveil increasing species diversity and carbapenemae‑resistance: A retrospective and genomic epidemiology study Open
Serratia spp., an opportunistic pathogen, has increasingly acquired resistance, particularly the emergence of carbapenemase-resistance. However, previous studies have focused on fragmented surveillance and have not conducted overall correl…
View article: Case Report: Clinical and Genetic Characteristics of Pearson Syndrome in a Chinese Boy and 139 Patients
Case Report: Clinical and Genetic Characteristics of Pearson Syndrome in a Chinese Boy and 139 Patients Open
Background: Pearson’s syndrome (PS) is a rare multi-system disorder caused by mitochondrial DNA deletion. Most PS cases in the literature are individual reports, and there is a lack of systematic analysis of clinical features and gene muta…
View article: Maternal obesity inhibits placental angiogenesis by down-regulating the SIRT1/PGC-1α pathway
Maternal obesity inhibits placental angiogenesis by down-regulating the SIRT1/PGC-1α pathway Open
The results suggest that maternal obesity impairs placental angiogenesis. They also provide experimental evidence that activation of the SIRT1/PGC-1α signaling pathway improves angiogenesis in vitro.
View article: Effect of high-fat diet for rats at different stages on glucose and lipid metabolism in offspring and related mechanisms.
Effect of high-fat diet for rats at different stages on glucose and lipid metabolism in offspring and related mechanisms. Open
High-fat diet for rats at different stages before and after pregnancy has different effects on glucose and lipid metabolism of offspring rats, and high-fat diet before pregnancy and during pregnancy and lactation has the greatest effect. T…
View article: Identification of novel <i>ACAN</i> mutations in two Chinese families and genotype–phenotype correlation in patients with 74 pathogenic <i>ACAN</i> variations
Identification of novel <i>ACAN</i> mutations in two Chinese families and genotype–phenotype correlation in patients with 74 pathogenic <i>ACAN</i> variations Open
Background ACAN (OMIM 155760) is located on chromosome 15q26 and encodes the production of aggrecan. Aggrecan is a large chondroitin sulfate proteoglycan with a molecular weight of 254 kDa and contains 2530 amino acids. It is a critical st…
View article: Relationship between the number of hospital pharmacists and hospital pharmaceutical expenditure: a macro-level panel data model of fixed effects with individual and time
Relationship between the number of hospital pharmacists and hospital pharmaceutical expenditure: a macro-level panel data model of fixed effects with individual and time Open
Background The rapid increase in pharmaceutical expenditure (PE) has been a main problem of global healthcare reform for decades. Previous studies demonstrated that pharmacists play an indispensable role in controlling PE, but macro-resear…
View article: The Effects of Maternal Obesity on Porcine Placental Efficiency and Proteome
The Effects of Maternal Obesity on Porcine Placental Efficiency and Proteome Open
Maternal obesity is associated with impaired maternal metabolism and affects the developmental programming of the fetus. The placenta is dysfunctional when exposed to an obese intrauterine environment and can transduce and mediate detrimen…
View article: MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies
MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies Open
Pre-eclampsia (PE) is one of the leading causes of maternal and neonatal morbidity and mortality. In recent years, many studies have shown that microRNAs (miRNA) play important roles in the development of PE. However, the molecular pathoge…