Mengqi Tu
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View article: Calbindin-D28k deficiency mediates tau-driven hippocampal hyperexcitement and cognitive impairment
Calbindin-D28k deficiency mediates tau-driven hippocampal hyperexcitement and cognitive impairment Open
Background Medial temporal lobe hyperexcitation or seizures originating from hippocampus are frequently observed in Alzheimer's disease (AD) patients, contributing to accelerated cognitive decline. Given the hippocampus's role as an early …
View article: Spastic pelvic floor syndrome and puborectalis syndrome: The different stages of the same disease
Spastic pelvic floor syndrome and puborectalis syndrome: The different stages of the same disease Open
The diagnosis and treatment of puborectalis syndrome (PRS) and spastic pelvic floor syndrome (SPFS) are still up for debate. This study aims to investigate examine the similarities and differences between PRS and SPFS. This study recruited…
View article: Clot Meniscus Sign Is Associated With Thrombus Permeability and Choice of Mechanical Thrombectomy Technique in Acute Middle Cerebral Artery Occlusion
Clot Meniscus Sign Is Associated With Thrombus Permeability and Choice of Mechanical Thrombectomy Technique in Acute Middle Cerebral Artery Occlusion Open
Background and Purpose The method of mechanical thrombectomy (MT) is related to vascular anatomy and stroke etiology. Meniscus sign and thrombus permeability as imaging markers may be instructive for the selection of MT. This study aims to…
View article: Analysis of the Risk Factors for Mortality in Adult COVID-19 Patients in Wuhan: A Multicenter Study
Analysis of the Risk Factors for Mortality in Adult COVID-19 Patients in Wuhan: A Multicenter Study Open
Objectives: An outbreak of coronavirus disease (COVID-19) in 2019 in Wuhan, China, has spread quickly worldwide. However, the risk factors associated with COVID-19-related mortality remain controversial. Methods: A total of 245 adult patie…
View article: Identifying sarcopenia in advanced non‐small cell lung cancer patients using skeletal muscle <scp>CT</scp> radiomics and machine learning
Identifying sarcopenia in advanced non‐small cell lung cancer patients using skeletal muscle <span>CT</span> radiomics and machine learning Open
Background Sarcopenia has been confirmed as a poor prognostic indicator of lung cancer. However, the lack of abdominal computed tomography (CT) hindered the application to assess the status of sarcopenia. The purpose of this study was to a…
View article: Long Non-Coding RNA PART1 Promotes Proliferation, Migration and Invasion of Hepatocellular Carcinoma Cells via miR-149-5p/MAP2K1 Axis
Long Non-Coding RNA PART1 Promotes Proliferation, Migration and Invasion of Hepatocellular Carcinoma Cells via miR-149-5p/MAP2K1 Axis Open
Chao Zhou,1,* Pu Wang,1,* Mengtian Tu,1 Yi Huang,2 Fei Xiong,1 Yue Wu3 1Department of Gastroenterology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, People’s Republic of China; 2Depar…
View article: Thin-Section Chest CT Imaging of COVID-19 Pneumonia: A Comparison Between Patients with Mild and Severe Disease
Thin-Section Chest CT Imaging of COVID-19 Pneumonia: A Comparison Between Patients with Mild and Severe Disease Open
Ground-glass opacities with or without consolidation in a peripheral and basilar predominant distribution were the most common findings in COVID-19 pneumonia. Patients with the severe form of the disease had more extensive opacification of…
View article: Correction: Characterization of long noncoding RNA and messenger RNA signatures in melanoma tumorigenesis and metastasis
Correction: Characterization of long noncoding RNA and messenger RNA signatures in melanoma tumorigenesis and metastasis Open
[This corrects the article DOI: 10.1371/journal.pone.0172498.].
View article: The diagnostic performance of perfusion MRI for differentiating glioma recurrence from pseudoprogression
The diagnostic performance of perfusion MRI for differentiating glioma recurrence from pseudoprogression Open
While perfusion MRI is not the ideal diagnostic method for differentiating glioma recurrence from pseudoprogression, it could improve diagnostic accuracy. Therefore, further research on combining perfusion MRI with other imaging modalities…
View article: Characterization of long noncoding RNA and messenger RNA signatures in melanoma tumorigenesis and metastasis
Characterization of long noncoding RNA and messenger RNA signatures in melanoma tumorigenesis and metastasis Open
[This corrects the article DOI: 10.1371/journal.pone.0172498.].