Mengsha Li
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View article: Radiation-hardened dendritic-like nanocomposite films with ultrahigh capacitive energy density
Radiation-hardened dendritic-like nanocomposite films with ultrahigh capacitive energy density Open
Electrostatic dielectric capacitors are critical components in advanced electronic and electrical systems owing to their high-power density and ultrafast charge-discharge capability. However, achieving ultrahigh energy storage performance …
View article: Atomic insights into dynamic integration of morphology and surface chemistry on the growth mechanism of ternary Pt-based nanocatalysts
Atomic insights into dynamic integration of morphology and surface chemistry on the growth mechanism of ternary Pt-based nanocatalysts Open
View article: Computational Study on the Reaction Mechanism of 5‐Enolpyruvylshikimate‐3‐phosphate Synthase from <i>Nicotiana Tabacum</i>
Computational Study on the Reaction Mechanism of 5‐Enolpyruvylshikimate‐3‐phosphate Synthase from <i>Nicotiana Tabacum</i> Open
5‐Enolpyruvylshikimate‐3‐phosphate synthase (EPSPS) catalyzes the conversion of 5‐enolpyruvate (PEP) and shikimic acid phosphate (S3P) to 5‐enolpyruvylshikimic acid‐3‐phosphate (EPSP), releasing inorganic phosphate. This reaction is the si…
View article: Robust Superconductivity in Infinite‐Layer Nickelates (Adv. Sci. 37/2024)
Robust Superconductivity in Infinite‐Layer Nickelates (Adv. Sci. 37/2024) Open
Superconductors In article number 2305252, Huaqian Leng, Mengsha Li, Liang Qiao, and co‐workers demonstrate a reversible transition between the perovskite Nd(0.8)Sr(0.2)NiO(3) and the infinite‐layer Nd(0.8)Sr(0.2)NiO(2) thin films without …
View article: Robust Superconductivity in Infinite‐Layer Nickelates
Robust Superconductivity in Infinite‐Layer Nickelates Open
The recent discovery of nickelate superconductivity represents an important step toward understanding the four‐decade mastery of unconventional high‐temperature superconductivity. However, the synthesis of the infinite‐layer nickelate supe…
View article: Enhancing the activity of zearalenone lactone hydrolase toward the more toxic α-zearalanol via a single-point mutation
Enhancing the activity of zearalenone lactone hydrolase toward the more toxic α-zearalanol via a single-point mutation Open
The mycotoxins zearalenone (ZEN) and its derivatives pose a significant threat to food safety. Here, we present a highly promising ZEN lactone hydrolase (ZHD), ZHDAY3, which is capable of efficiently degrading both ZEN and the more toxic d…
View article: Improved Sofc Performance by Enhancing Cathode/Electrolyte Bonding and Grain Refinement of Cathode
Improved Sofc Performance by Enhancing Cathode/Electrolyte Bonding and Grain Refinement of Cathode Open
View article: High Performance Thermal Expansion Offset Lscf-Szm Cathodes of It-Sofcs
High Performance Thermal Expansion Offset Lscf-Szm Cathodes of It-Sofcs Open
View article: Improved Sofc Performance by Enhancing Cathode/Electrolyte Bonding and Grain Refinement of Composite Cathode
Improved Sofc Performance by Enhancing Cathode/Electrolyte Bonding and Grain Refinement of Composite Cathode Open
View article: Halide‐Driven Synthetic Control of InSb Colloidal Quantum Dots Enables Short‐Wave Infrared Photodetectors
Halide‐Driven Synthetic Control of InSb Colloidal Quantum Dots Enables Short‐Wave Infrared Photodetectors Open
In the III–V family of colloidal quantum dot (CQD) semiconductors, InSb promises access to a wider range of infrared wavelengths compared to many light‐sensing material candidates. However, achieving the necessary size, size‐dispersity, an…
View article: LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization
LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization Open
LDHA-mediated metabolic reprogramming promoted CM proliferation by alleviating ROS and inducing M2 macrophage polarization, indicating that LDHA might be an effective target for promoting cardiac repair post-MI.
View article: Large Rashba Spin-orbit Effect by Orbital Engineering at SrTiO3 based Correlated Interfaces.
Large Rashba Spin-orbit Effect by Orbital Engineering at SrTiO3 based Correlated Interfaces. Open
Large spin-orbit effect is an essential element for efficient spin-orbitronics that utilizes the interplay between charge and spin degree of freedom. This spin-orbit effect is generally small in heavy-metal-based or requires large external…
View article: Facilitating the Deprotonation of OH to O through Fe<sup>4+</sup>‐Induced States in Perovskite LaNiO<sub>3</sub> Enables a Fast Oxygen Evolution Reaction
Facilitating the Deprotonation of OH to O through Fe<sup>4+</sup>‐Induced States in Perovskite LaNiO<sub>3</sub> Enables a Fast Oxygen Evolution Reaction Open
Aliovalent doping is widely adopted to tune the electronic structure of transition‐metal oxides for design of low‐cost, active electrocatalysts. Here, using single‐crystalline thin films as model electrocatalysts, the structure‐activity re…
View article: Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway
Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway Open
Post-translational modification (PTM) by small ubiquitin-like modifier (SUMO) is a key regulator of cell proliferation and can be readily reversed by a family of SUMO-specific proteases (SENPs), making SUMOylation an ideal regulatory mecha…
View article: Phase Diagram and Superconducting Dome of Infinite-Layer <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi>Nd</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mo>−</mml:mo><mml:mi>x</mml:mi></mml:mrow></mml:msub><mml:msub><mml:mrow><mml:mi>Sr</mml:mi></mml:mrow><mml:mrow><mml:mi>x</mml:mi></mml:mrow></mml:msub><mml:msub><mml:mrow><mml:mi>NiO</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> Thin Films
Phase Diagram and Superconducting Dome of Infinite-Layer Thin Films Open
Infinite-layer Nd_{1-x}Sr_{x}NiO_{2} thin films with Sr doping level x from 0.08 to 0.3 are synthesized and investigated. We find a superconducting dome x between 0.12 and 0.235 accompanied by a weakly insulating behavior in both under- an…
View article: Hydrogen sulfide‐loaded microbubbles combined with ultrasound mediate thrombolysis and simultaneously mitigate ischemia‐reperfusion injury in a rat hindlimb model
Hydrogen sulfide‐loaded microbubbles combined with ultrasound mediate thrombolysis and simultaneously mitigate ischemia‐reperfusion injury in a rat hindlimb model Open
hs-Mbs+US effectively dissolved both white and red macrothrombi and simultaneously alleviated skeletal muscle IRI through the US-triggered, organ-specific release of H2 S. This integrated therapeutic strategy holds promise for t…
View article: Bulk Spin Torque‐Driven Perpendicular Magnetization Switching in <i>L</i>1<sub>0</sub> FePt Single Layer
Bulk Spin Torque‐Driven Perpendicular Magnetization Switching in <i>L</i>1<sub>0</sub> FePt Single Layer Open
Due to its inherent superior perpendicular magnetocrystalline anisotropy, the FePt in L 1 0 phase enables magnetic storage and memory devices with ultrahigh capacity. However, reversing the FePt magnetic state, and therefore encoding infor…
View article: Characteristic Lengths of Interlayer Charge Transfer in Correlated Oxide Heterostructures
Characteristic Lengths of Interlayer Charge Transfer in Correlated Oxide Heterostructures Open
Using interlayer interaction to control functional heterostructures with atomic-scale designs has become one of the most effective interface-engineering strategies nowadays. Here, we demonstrate the effect of a crystalline LaFeO3
View article: Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation
Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation Open
Inducing cardiomyocyte proliferation is a hopeful approach for cardiac regeneration following myocardial infarction. Previous studies have shown that p21 inhibits the cardiomyocyte proliferation and cardiac regeneration. Deacetylation of p…
View article: Observation of an Emerging Charged Domain Wall at a Non-ferroelectric Heterointerface with Aberration-corrected STEM
Observation of an Emerging Charged Domain Wall at a Non-ferroelectric Heterointerface with Aberration-corrected STEM Open
Journal Article Observation of an Emerging Charged Domain Wall at a Non-ferroelectric Heterointerface with Aberration-corrected STEM Get access Mengsha Li, Mengsha Li Department of Materials Science and Engineering, National University of …
View article: Long noncoding RNA GAS5 induces abdominal aortic aneurysm formation by promoting smooth muscle apoptosis
Long noncoding RNA GAS5 induces abdominal aortic aneurysm formation by promoting smooth muscle apoptosis Open
Objective: Long noncoding RNAs (lncRNAs) may serve as specific targets for the treatment of abdominal aortic aneurysms (AAAs). LncRNA GAS5, functionally associated with smooth muscle cell (SMC) apoptosis and proliferation, is likely…
View article: SM22α (Smooth Muscle 22α) Prevents Aortic Aneurysm Formation by Inhibiting Smooth Muscle Cell Phenotypic Switching Through Suppressing Reactive Oxygen Species/NF-κB (Nuclear Factor-κB)
SM22α (Smooth Muscle 22α) Prevents Aortic Aneurysm Formation by Inhibiting Smooth Muscle Cell Phenotypic Switching Through Suppressing Reactive Oxygen Species/NF-κB (Nuclear Factor-κB) Open
Objective— Vascular smooth muscle cell phenotypic transition plays a critical role in the formation of abdominal aortic aneurysms (AAAs). SM22α (smooth muscle 22α) has a vital role in maintaining the smooth muscle cell phenotype and is dow…
View article: Inhibition of AZIN2-sv induces neovascularization and improves prognosis after myocardial infarction by blocking ubiquitin-dependent talin1 degradation and activating the Akt pathway
Inhibition of AZIN2-sv induces neovascularization and improves prognosis after myocardial infarction by blocking ubiquitin-dependent talin1 degradation and activating the Akt pathway Open
Bach1-activated AZIN2-sv could participate in angiogenesis by promoting the PSMC5-mediated ubiquitination-dependent degradation of Tln1 and blocking the miR-214/PTEN/Akt pathway. Inhibition of AZIN2-sv induced angiogenesis and myocardial r…
View article: Loss of long non-coding RNA CRRL promotes cardiomyocyte regeneration and improves cardiac repair by functioning as a competing endogenous RNA
Loss of long non-coding RNA CRRL promotes cardiomyocyte regeneration and improves cardiac repair by functioning as a competing endogenous RNA Open
Long noncoding RNAs (lncRNAs) play critical roles in the development of myocardial hypertrophy and may stimulate endogenous myocardial regeneration to prevent heart failure after myocardial infarction (MI). However, whether lncRNAs are inv…
View article: Material structure, properties, and dynamics through scanning transmission electron microscopy
Material structure, properties, and dynamics through scanning transmission electron microscopy Open
Scanning transmission electron microscopy (STEM) has advanced rapidly in the last decade thanks to the ability to correct the major aberrations of the probe-forming lens. Now, atomic-sized beams are routine, even at accelerating voltages a…
View article: Loss of AZIN2 splice variant facilitates endogenous cardiac regeneration
Loss of AZIN2 splice variant facilitates endogenous cardiac regeneration Open
The newly discovered AZIN2-sv suppressed endogenous cardiac regeneration by targeting the PTEN/Akt pathway. Thus, AZIN2-sv may be a novel therapeutic target for preventing and treating heart failure.
View article: Complete regression of cutaneous metastases with systemic immune response in a patient with triple negative breast cancer receiving p53MVA vaccine with pembrolizumab
Complete regression of cutaneous metastases with systemic immune response in a patient with triple negative breast cancer receiving p53MVA vaccine with pembrolizumab Open
A heavily pretreated patient with triple negative breast cancer distinguished by cutaneous metastases received p53MVA vaccine in combination with pembrolizumab. Her cutaneous metastases regressed and after 2 cycles of therapy, a skin biops…