Mengtong Xu
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View article: Rationale, design and protocol for risk factors for stroke in patients with non-valvular atrial fibrillation in China: a nationwide registry (REFINE registry)
Rationale, design and protocol for risk factors for stroke in patients with non-valvular atrial fibrillation in China: a nationwide registry (REFINE registry) Open
Introduction Atrial fibrillation (AF), the most common sustained arrhythmia globally, necessitates effective strategies for stroke prevention. Although current risk stratification tools, such as the CHA₂DS₂-VASc score, are widely used to g…
View article: LINS: A general medical Q&A framework for enhancing the quality and credibility of LLM-generated responses
LINS: A general medical Q&A framework for enhancing the quality and credibility of LLM-generated responses Open
Large language models can lighten the workload of clinicians and patients, yet their responses often include fabricated evidence, outdated knowledge, and insufficient medical specificity. We introduce a general retrieval-augmented question…
View article: Prognostic Value of Multiple Circulating Biomarkers for Ventricular Arrhythmias in Left Ventricular Hypertrabeculation ― Longitudinal Cohort Study ―
Prognostic Value of Multiple Circulating Biomarkers for Ventricular Arrhythmias in Left Ventricular Hypertrabeculation ― Longitudinal Cohort Study ― Open
Big endothelin-1 concentrations and the location of hypertrabeculation can help with risk stratification for VAs in LVHT.
View article: Outcomes in Catheter Ablation of Sustained Ventricular Tachycardia in Myocarditis Compared with Ischemic Heart Disease
Outcomes in Catheter Ablation of Sustained Ventricular Tachycardia in Myocarditis Compared with Ischemic Heart Disease Open
Background: The substrates for arrhythmias in myocarditis and ischemic heart disease (IHD) are different, but it is yet to be determined whether there is a difference in outcomes following catheter ablation (CA) for ventricular tachycardia…
View article: T Lymphocyte-Macrophage Hybrid Membrane-Coated Biomimetic Nanoparticles Alleviate Myocarditis via Suppressing Pyroptosis by Targeting Gene Silencing
T Lymphocyte-Macrophage Hybrid Membrane-Coated Biomimetic Nanoparticles Alleviate Myocarditis via Suppressing Pyroptosis by Targeting Gene Silencing Open
The siIRF1 nanotherapeutic approach shows potential for attenuating myocardial inflammation and mitigating myocarditis progression. Our study highlights the promise of this customized biomimetic nano-delivery system for treating inflammato…
View article: ABLE-SCORE, a simplified risk score for major adverse cardiovascular outcomes in left ventricular hypertrabeculation: a multicenter longitudinal cohort study
ABLE-SCORE, a simplified risk score for major adverse cardiovascular outcomes in left ventricular hypertrabeculation: a multicenter longitudinal cohort study Open
View article: T Lymphocyte-Macrophage Hybrid Membrane-Coated Biomimetic Nanoparticles Alleviate Myocarditis via Suppressing Pyroptosis by Targeting Gene Silencing
T Lymphocyte-Macrophage Hybrid Membrane-Coated Biomimetic Nanoparticles Alleviate Myocarditis via Suppressing Pyroptosis by Targeting Gene Silencing Open
Utilizing small interfering RNA (siRNA) for gene silencing presents a viable strategy for treating human diseases, including cardiovascular disorders. However, the strategic targeting and delivery of siRNA therapeutics to desired tissues o…
View article: ABLE-SCORE, a simplified risk score for major adverse cardiovascular outcomes in left ventricular noncompaction: a multicenter longitudinal cohort study
ABLE-SCORE, a simplified risk score for major adverse cardiovascular outcomes in left ventricular noncompaction: a multicenter longitudinal cohort study Open
Background Left ventricular noncompaction (LVNC) is a heterogeneous entity with life-threatening complications and variable prognosis. However, there are limited prediction models available to identify individuals at high risk of adverse o…
View article: Prognostic Value of Multiple Circulating Biomarkers for Ventricular Arrhythmias in Left Ventricular Hypertrabeculation: A Longitudinal Cohort Study
Prognostic Value of Multiple Circulating Biomarkers for Ventricular Arrhythmias in Left Ventricular Hypertrabeculation: A Longitudinal Cohort Study Open
View article: Oral squamous cell carcinomas: state of the field and emerging directions
Oral squamous cell carcinomas: state of the field and emerging directions Open
View article: Exosomal miRNAs contribute to coal dust particle-induced pulmonary fibrosis in rats
Exosomal miRNAs contribute to coal dust particle-induced pulmonary fibrosis in rats Open
Coal workers’ pneumoconiosis (CWP) is a fatal occupational disease caused by inhalation of coal dust particles, which leads to progressive pulmonary fibrosis. Recently, as new signal carriers for intercellular communication, exosomal miRNA…