Mengying Deng
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View article: Association between antibiotics and treatment efficacy in metastatic urothelial carcinoma patients
Association between antibiotics and treatment efficacy in metastatic urothelial carcinoma patients Open
Background Antibiotic therapy (ABT)-induced dysbiosis may affect the efficacy of immune checkpoint inhibitors (ICI) therapy. We investigated the association between ABT and real-world overall survival (rwOS) and progression-free survival (…
View article: Racial/Ethnic Differences and Effects of Clinical/Socioeconomic Factors on Time from Diagnosis to Treatment in Pancreatic Cancer
Racial/Ethnic Differences and Effects of Clinical/Socioeconomic Factors on Time from Diagnosis to Treatment in Pancreatic Cancer Open
View article: Mutations of the BRCA1/2 genes in patients with breast cancer do not alter treatment outcomes following radiation therapy
Mutations of the BRCA1/2 genes in patients with breast cancer do not alter treatment outcomes following radiation therapy Open
View article: Factors Associated With Racial and Ethnic Disparities in Locally Advanced Rectal Cancer Outcomes
Factors Associated With Racial and Ethnic Disparities in Locally Advanced Rectal Cancer Outcomes Open
Importance Hispanic and non-Hispanic Black patients receiving neoadjuvant therapy and surgery for locally advanced rectal cancer (LARC) achieve less favorable clinical outcomes than non-Hispanic White patients, but the source of this dispa…
View article: Attitudes About the Human Papillomavirus Vaccine Among Patients With and Without Cervical Dysplasia
Attitudes About the Human Papillomavirus Vaccine Among Patients With and Without Cervical Dysplasia Open
Objectives The aims of the study are to examine the perception of the human papillomavirus (HPV) vaccine among those with and without a history of cervical dysplasia and to examine perceptions of the vaccine for their children. Materials a…
View article: Survey of Surgeon-reported Postoperative Protocols for Deep Inferior Epigastric Perforator Flap in Breast Reconstruction
Survey of Surgeon-reported Postoperative Protocols for Deep Inferior Epigastric Perforator Flap in Breast Reconstruction Open
Background: The use of deep inferior epigastric perforator (DIEP) flaps is a well-established breast reconstruction technique. Methods: A 29-question survey was e-mailed to 3186 active American Society of Plastic Surgeons members, aiming t…
View article: P2.07-04 Genomic Subtypes of EGFR-Mutant NSCLC and Real-World Progression-Free Survival (rwPFS) with Immunotherapy (IO)
P2.07-04 Genomic Subtypes of EGFR-Mutant NSCLC and Real-World Progression-Free Survival (rwPFS) with Immunotherapy (IO) Open
View article: The Impact of Mutations of BRCA1/2 Genes in Patients with Breast Cancer on Treatment Outcomes Following Radiation Therapy (RT)
The Impact of Mutations of BRCA1/2 Genes in Patients with Breast Cancer on Treatment Outcomes Following Radiation Therapy (RT) Open
View article: A dosimetric analysis of rectal hydrogel spacer use in patients with recurrent prostate cancer undergoing salvage high-dose-rate brachytherapy
A dosimetric analysis of rectal hydrogel spacer use in patients with recurrent prostate cancer undergoing salvage high-dose-rate brachytherapy Open
View article: OUTCOMES OF AUTOLOGOUS TRANSPLANT, ALLOGENEIC TRANSPLANT, AND CAR T CELL THERAPY IN TP53 ALTERED MANTLE CELL LYMPHOMA: A MULTI‐INSTITUTION RETROSPECTIVE ANALYSIS
OUTCOMES OF AUTOLOGOUS TRANSPLANT, ALLOGENEIC TRANSPLANT, AND CAR T CELL THERAPY IN TP53 ALTERED MANTLE CELL LYMPHOMA: A MULTI‐INSTITUTION RETROSPECTIVE ANALYSIS Open
Introduction: TP53 alterations are associated with poor prognosis in mantle cell lymphoma (MCL). In trials of intensive chemotherapy and autologous hematopoietic cell transplant (auto-HCT), patients (pts) with TP53 mutations had an overall…
View article: Gender differences in cardiothoracic surgery letters of recommendation
Gender differences in cardiothoracic surgery letters of recommendation Open
View article: Timing of Unplanned Reoperation After Lower Extremity Free Flap Reconstruction
Timing of Unplanned Reoperation After Lower Extremity Free Flap Reconstruction Open
Background Advancements in lower extremity (LE) microsurgery have allowed for the expansion of indications for LE reconstructions. This project aims to better understand the temporal pattern and risk factors associated with LE free flap fa…
View article: The association between sense of coherence and health outcomes among community-dwelling older adults: a systematic review
The association between sense of coherence and health outcomes among community-dwelling older adults: a systematic review Open
Objective: The objective of this study was to systematically review evidence of the association between the sense of coherence (SOC) and health outcomes in community-dwelling older adults. Methods: Six databases, including PubMed, Web of S…
View article: Assessing Oncologists’ Adoption of Biomarker Testing in Metastatic Colorectal Cancer Using Real-World Data
Assessing Oncologists’ Adoption of Biomarker Testing in Metastatic Colorectal Cancer Using Real-World Data Open
Background Despite national guideline recommendations for universal biomarker testing (KRAS, NRAS, BRAF, and mismatch repair and microsatellite instability [MMR/MSI]) in all patients with metastatic colorectal cancer (mCRC), little is know…
View article: Critical Importance of the First Postoperative Days After Head and Neck Free Flap Reconstruction
Critical Importance of the First Postoperative Days After Head and Neck Free Flap Reconstruction Open
Background Head and neck free flaps remain associated with considerable rates of take-back and prolonged hospital length of stay. However, there have been no studies on a national level benchmarking the timeline and predictors of head and …
View article: Neoadjuvant Chemotherapy with Accelerated Methotrexate, Vinblastine, Doxorubicin, and Cisplatin in Patients with Muscle-invasive Bladder Cancer: A Retrospective Age-stratified Analysis on Safety and Efficacy
Neoadjuvant Chemotherapy with Accelerated Methotrexate, Vinblastine, Doxorubicin, and Cisplatin in Patients with Muscle-invasive Bladder Cancer: A Retrospective Age-stratified Analysis on Safety and Efficacy Open
View article: Comparative Outcomes of Second-line Topoisomerase-I Inhibitor Therapies on Neuroendocrine Carcinoma
Comparative Outcomes of Second-line Topoisomerase-I Inhibitor Therapies on Neuroendocrine Carcinoma Open
View article: Total neoadjuvant therapy for pancreatic adenocarcinoma increases probability for a complete pathologic response
Total neoadjuvant therapy for pancreatic adenocarcinoma increases probability for a complete pathologic response Open
View article: Clinical Significance of Total Radiation Dose for Patients With Treatment Delays in Stage III Non-Small Cell Lung Cancer
Clinical Significance of Total Radiation Dose for Patients With Treatment Delays in Stage III Non-Small Cell Lung Cancer Open
View article: Effect of Adjuvant Chemotherapy After SBRT for Node Negative, Non-Metastatic Non-Small Cell Lung Cancer
Effect of Adjuvant Chemotherapy After SBRT for Node Negative, Non-Metastatic Non-Small Cell Lung Cancer Open
View article: Postoperative Complications Associated with the Choice of Reconstruction in Head and Neck Cancer: An Outcome Analysis of 4,712 Patients from the ACS-NSQIP Database
Postoperative Complications Associated with the Choice of Reconstruction in Head and Neck Cancer: An Outcome Analysis of 4,712 Patients from the ACS-NSQIP Database Open
Background Microsurgical free flaps have largely supplanted pedicled flaps as the gold standard for head and neck cancer reconstruction. However, incidence of postoperative complications after accounting for patient comorbidities based on …
View article: Early Prostate-Specific Antigen Kinetics for Low- and Intermediate-Risk Prostate Cancer Treated With Definitive Radiation Therapy
Early Prostate-Specific Antigen Kinetics for Low- and Intermediate-Risk Prostate Cancer Treated With Definitive Radiation Therapy Open
View article: Safety of neoadjuvant chemotherapy in patients with muscle‐invasive bladder cancer and malignant ureteric obstruction
Safety of neoadjuvant chemotherapy in patients with muscle‐invasive bladder cancer and malignant ureteric obstruction Open
Objectives To determine whether patients with carcinoma invading bladder muscle (MIBC) and ureteric obstruction can safely receive cisplatin‐based neoadjuvant chemotherapy (C‐NAC), and to determine whether such patients require relief of o…
View article: Does the false‐negative rate for 1 or 2 negative sentinel nodes after neo‐adjuvant chemotherapy translate into a high local recurrence rate?
Does the false‐negative rate for 1 or 2 negative sentinel nodes after neo‐adjuvant chemotherapy translate into a high local recurrence rate? Open
Prospective trials demonstrate that sentinel node (SN) biopsy after neo-adjuvant chemotherapy (NACT) has a significant false-negative rate (FNR) when only 1 or 2 SNs are removed. It is unknown whether this increased FNR correlates with an …
View article: Cystoscopy and Systematic Bladder Tissue Sampling in Predicting pT0 Bladder Cancer: A Prospective Trial
Cystoscopy and Systematic Bladder Tissue Sampling in Predicting pT0 Bladder Cancer: A Prospective Trial Open
Approximately 1 of 4 patients with seeT0 at the time of radical cystectomy harbored residual muscle invasive bladder cancer. These prospective data definitively confirm major limitations of endoscopic assessment for pT0 bladder cancer. Fut…
View article: Early postoperative outcomes in implant, pedicled, and free flap reconstruction for breast cancer: an analysis of 23,834 patients from the ACS-NSQIP datasets
Early postoperative outcomes in implant, pedicled, and free flap reconstruction for breast cancer: an analysis of 23,834 patients from the ACS-NSQIP datasets Open
View article: Understanding benefit finding among patients with colorectal cancer: a longitudinal study
Understanding benefit finding among patients with colorectal cancer: a longitudinal study Open
View article: Postoperative Complications Associated With Choice of Reconstruction in Head and Neck Cancer: An Outcome Analysis From the American College of Surgeons-National Surgical Quality Improvement Database
Postoperative Complications Associated With Choice of Reconstruction in Head and Neck Cancer: An Outcome Analysis From the American College of Surgeons-National Surgical Quality Improvement Database Open
BACKGROUND: Microsurgical free flaps have supplanted myocutaneous pedicled flaps as the gold standard for head and neck cancer reconstruction in terms of lending a superior functional and aesthetic result.1–4 However, factors relating to p…
View article: Primary tumor characteristics and next‐generation sequencing mutations as biomarkers for melanoma immunotherapy response
Primary tumor characteristics and next‐generation sequencing mutations as biomarkers for melanoma immunotherapy response Open
Introduction Considerable advances in melanoma have been realized through immunotherapy. The principal aim was to determine whether primary tumor characteristics or next‐generation sequencing (NGS) could serve as markers of immunotherapy r…
View article: Pembrolizumab monotherapy in patients with previously treated metastatic high-grade neuroendocrine neoplasms: joint analysis of two prospective, non-randomised trials
Pembrolizumab monotherapy in patients with previously treated metastatic high-grade neuroendocrine neoplasms: joint analysis of two prospective, non-randomised trials Open
Background Metastatic high-grade neuroendocrine neoplasms (G3NENs) have limited treatment options after progression on platinum-based therapy. We addressed the role of Pembrolizumab in patients with previously treated metastatic G3NENs. Me…