Explanipedia

High-resolution spatial transcriptomics in fixed tissue using a cost-effective PCL-seq workflow Open

Xue Dong, Mengzhu Hu, Xiaonan Cui, Wenjian Zhou, Jinzhen Cai , et al. · 2025

The spatial heterogeneity of gene expression has driven the development of diverse spatial transcriptomics technologies. Here, we present photocleavage and ligation sequencing (PCL-seq), a spatial indexing method utilizing a light-controll…

Rotating Dynamics Analysis of Defective Homogeneous Sphere in Optical Tweezers Open

Qi Zhu, Huizhu Hu, Hang Shi, Mengzhu Hu, Wenqiang Li , et al. · 2025

An optically levitated rotating sphere is an ultrasensitive torque sensor. In this article, a method was presented to apply a specially manufactured defective hollow homogeneous sphere as a stable rotor. The numerical relationship between …

Theoretical Study on Low-Chirp Directly Modulated DFB Lasers with (110)-Oriented Quantum Well Open

Jianwei Li, Mengzhu Hu, Xinyang Su, Yanting Liu, Ke Zhan · 2025

The low-chirp operation of distributed feedback lasers is highly desirable in high-speed and high-bit rate optical transmission. In this article, we address this issue by theoretically investigating the possibility of further a reduction i…

Large field of view and spatial region of interest transcriptomics in fixed tissue Open

Xiaonan Cui, Dong Xue, Mengzhu Hu, Wenjian Zhou, Weiyang Shi · 2024

Expression profiling in spatially defined regions is crucial for systematically understanding tissue complexity. Here, we report a method of photo-irradiation for in-situ barcoding hybridization and ligation sequencing, named PBHL-seq, whi…

AAB-seq: An antigen-specific and affinity-readable high-throughput BCR sequencing method Open

Mengzhu Hu, Qiuyu Lian, Xiaonan Cui, Dongfeng Xue, Hong-Yi Xin , et al. · 2024

B-cell receptor (BCR) sequencing is a powerful antibody discovery tool but current methodology is often inefficient, and lead generation often requires the production and testing of numerous antibody candidates, and it is difficult to prov…

PCL-seq: enhanced high-resolution transcriptomic profiling of region of interest in fresh frozen and FFPE tissues Open

Dong Xue, Xiaonan Cui, Mengzhu Hu, Wenjian Zhou, Weiyang Shi · 2024

The spatial heterogeneity of gene expression has propelled the development of multiple spatial transcriptomics technologies. Here, we present p hoto c leavage and l igation sequencing (PCL-seq), an method for spatial indexing using a light…

Theoretical Analysis and Experimental Verification of the Influence of Polarization on Counter-Propagating Optical Tweezers Open

Ming Chen, Wenqiang Li, Jianyu Yang, Mengzhu Hu, Shidong Xu , et al. · 2023

Counter-propagating optical tweezers are experimental platforms for the frontier exploration of science and precision measurement. The polarization of the trapping beams significantly affects the trapping status. Using the T-matrix method,…

Analysis of Impurities in Sulfur Hexafluoride Gas via Gas Chromatography Based on Enhanced Plasma Detector Open

Zongchang Luo, Longfei Zhang, Bin Tang, Qinqin Liang, Jiqi Pan , et al. · 2023

An analytical method for detecting impurities in high-purity sulfur hexafluoride (SF 6 ) gas is established by using gas chromatography (GC) based on the enhanced plasma detector (EPD). The concentration of impurities (hydrogen, oxygen, ni…

Understanding Thermal Induced Escape Mechanism of Optically Levitated Sphere in Vacuum Open

Mengzhu Hu, Nan Li, Zhenhai Fu, Yizhou Zhang, Wenqiang Li , et al. · 2023

Understanding thermal induced escape mechanism of optically levitated sphere in vacuum Open

Mengzhu Hu, Nan Li, Zhenhai Fu, Yizhou Zhang, Wenqiang Li , et al. · 2022

The escape phenomenon, mainly caused by thermal effects, is known as an obstacle to the further practical application of optical levitation system in vacuum. Irregular photophoresis induced by thermal effects can act as an amplifier of Bro…

Study on thermal degradation and kinetic characteristics of insulating materials used in high voltage switchgear Open

Qinqin Liang, Bin Tang, Longfei Zhang, Zongchang Luo, Jialin Wang , et al. · 2022

This study adopts the FT-IR, DSC, TG and other methods, studied the commonly used in high-voltage switchgear XLPE, EP and organic silicone materials in the same heating rate under thermal degradation properties of three kinds of insulating…

Study on thermal degradation and kinetic characteristics of insulating materials used in high voltage switchgear Open

Qinqin Liang, Bin Tang, Longfei Zhang, Zongchang Luo, Jialin Wang , et al. · 2022

This study adopts the FT-IR, DSC, TG and other methods, studied the commonly used in high-voltage switchgear XLPE, EP and organic silicone materials in the same heating rate under thermal degradation properties of three kinds of insulating…

Formulation design of a new type of epoxy resin-based insulating adhesive and research on its high temperature resistance Open

Bin Tang, Longfei Zhang, Qinqin Liang, Zongchang Luo, Chuansheng Luo , et al. · 2022

A series of new epoxy resin adhesives were prepared by low viscosity bisphenol A epoxy resin E-44 and E-51as the matrix, low molecular polyamide 650# and phenolic modified JT-3008 as the curing agent, silicon micro powder and calcium carbo…

Research on Thermal Aging Behavior and Thermal Decomposition of Insulating Material XLPE Open

Mengzhu Hu, Bin Tang, Qinqin Liang, Zongchang Luo, Chuansheng Luo , et al. · 2022

In this paper, accelerated thermal aging experiment was used to simulate the thermal aging behavior of XLPE, and FT-IR, DSC, TG and other test techniques were used to characterize the materials with different aging periods. The results sho…

Formulation design of a new type of epoxy resin-based insulating adhesive and research on its high temperature resistance Open

Bin Tang, Longfei Zhang, Qinqin Liang, Zongchang Luo, Chuansheng Luo , et al. · 2022

A series of new epoxy resin adhesives were prepared by low viscosity bisphenol A epoxy resin E-44 and E-51as the matrix, low molecular polyamide 650# and phenolic modified JT-3008 as the curing agent, silicon micro powder and calcium carbo…

Research on Thermal Aging Behavior and Thermal Decomposition of Insulating Material XLPE Open

Mengzhu Hu, Bin Tang, Qinqin Liang, Zongchang Luo, Chuansheng Luo , et al. · 2022

In this paper, accelerated thermal aging experiment was used to simulate the thermal aging behavior of XLPE, and FT-IR, DSC, TG and other test techniques were used to characterize the materials with different aging periods. The results sho…

Analysis and Suppression of Laser Intensity Fluctuation in a Dual-Beam Optical Levitation System Open

Xia Wang, Qi Zhu, Mengzhu Hu, Wenqiang Li, Xingfan Chen , et al. · 2022

Levitated micro-resonators in vacuums have attracted widespread attention due to their application potential in precision force sensing, acceleration sensing, mass measurement and gravitational wave sensing. The optically levitated microsp…

3D calibration of microsphere position in optical tweezers using the back-focal-plane interferometry method Open

Wenqiang Li, Hanlin Zhang, Mengzhu Hu, Qi Zhu, Heming Su , et al. · 2021

This paper presents a method to directly calibrate the position of a trapped micro-sphere in optical tweezers utilizing its interference pattern formed at the back focal plane (BFP). Through finite difference time domain (FDTD) and scalar …

SCALABLE PREPARATION OF BROADBAND ULTRABLACK GRAPHITE NANONEEDLE SURFACES THROUGH SELF-MASKED ETCHING Open

Tingbiao Guo, Yaoran Sun, Sailing He, Jiang Yang, Mengzhu Hu , et al. · 2018

Broadband Absorption and Efficient Hot-Carrier Photovoltaic Conversion based on Sunlight-induced Non-radiative Decay of Propagating Surface Plasmon Polaritons Open

Mengzhu Hu, Liu Yang, Hao Dai, Sailing He · 2017

Localized surface plasmon polaritons (SPPs), which can decay non-radiatively into hot carriers, have been widely employed to extend the responses of traditional semiconductor-based photocatalytic and photovoltaic devices to sub-bandgap pho…

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