Matthew Williams
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View article: 795 Timings of Postoperative X-rays in Patients with in-situ Drains at the Nuffield Orthopaedic Centre (NOC) and their Effect on Discharge
795 Timings of Postoperative X-rays in Patients with in-situ Drains at the Nuffield Orthopaedic Centre (NOC) and their Effect on Discharge Open
Aim To assess current practices of obtaining postoperative X-rays in patients undergoing bone surgery with drains left in situ at the Nuffield Orthopaedic Centre (NOC) and understand the effect of delayed postoperative X-rays on discharge …
View article: CI at Scale: Lean, Green, and Fast
CI at Scale: Lean, Green, and Fast Open
Maintaining a "green" mainline branch, where all builds pass successfully, is crucial but challenging in fast-paced, large-scale software development environments, particularly with concurrent code changes in large monorepos. SubmitQueue, …
View article: Coming and going: A narrative review exploring the push-pull factors during nurses' careers
Coming and going: A narrative review exploring the push-pull factors during nurses' careers Open
Nuanced insight into motivations is needed to attract and retain a mix of nurse throughout their careers @ZEjebu @julia_philippou @JaneEball.
View article: The Challenges of Aortic Valve Management After Left Ventricular Assist Device Implantation
The Challenges of Aortic Valve Management After Left Ventricular Assist Device Implantation Open
Multiple treatment modalities exist for LVAD-induced aortic valve regurgitation, including open surgical and percutaneous strategies. With a tailored risk-adjusted approach, acceptable results may be achieved.
View article: What might make nurses stay? A protocol for discrete choice experiments to understand NHS nurses’ preferences at early-career and late-career stages
What might make nurses stay? A protocol for discrete choice experiments to understand NHS nurses’ preferences at early-career and late-career stages Open
Introduction Like many countries, England has a national shortage of registered nurses. Employers strive to retain existing staff, to ease supply pressures. Disproportionate numbers of nurses leave the National Health Services (NHS) both e…
View article: Effect of Dural-Puncture Epidural vs Standard Epidural for Epidural Extension on Onset Time of Surgical Anesthesia in Elective Cesarean Delivery
Effect of Dural-Puncture Epidural vs Standard Epidural for Epidural Extension on Onset Time of Surgical Anesthesia in Elective Cesarean Delivery Open
Importance Dural-puncture epidural (DPE) and standard epidural are common modes of neuraxial labor analgesia. Little is known about conversion of DPE-initiated labor analgesia to surgical anesthesia for cesarean delivery. Objective To dete…
View article: A Method for Producing 3D Printed Models of the Mediastinum
A Method for Producing 3D Printed Models of the Mediastinum Open
Plastic models are a useful resource for teaching macroscopic anatomy, but have several drawbacks.We present a method for the in-house production of high-fidelity anatomical models using real patient scans, which overcomes many of the limi…
View article: TH8.6 Thoracic sarcoma: three-year data from a tertiary referral centre
TH8.6 Thoracic sarcoma: three-year data from a tertiary referral centre Open
Aims The rarity of thoracic sarcomas leads to challenges in their diagnosis and evidence-based management. We aim to investigate the management and outcomes of primary thoracic sarcoma patients under the care of our tertiary centre Sarcoma…
View article: A single-institutional analysis of racial disparities in clinicopathologic characteristics, treatment selections, and outcomes in advanced-stage pancreatic cancer patients
A single-institutional analysis of racial disparities in clinicopathologic characteristics, treatment selections, and outcomes in advanced-stage pancreatic cancer patients Open
In this series of advanced PDA patients treated with contemporary chemotherapy, AA and White patients had comparable outcomes, but Asians had worse OS than White patients.
View article: Head and neck sarcoma: three-year data from a tertiary referral centre
Head and neck sarcoma: three-year data from a tertiary referral centre Open
Introduction Sarcomas of the head and neck are neoplasms arising from the embryonic mesenchyme. They are rare and heterogeneous in nature and are associated with significant morbidity and mortality. This study evaluates patients referred t…
View article: Occupational burnout following the first wave of coronavirus disease at a Welsh district general hospital
Occupational burnout following the first wave of coronavirus disease at a Welsh district general hospital Open
A survey was conducted to identify the prevalence of occupational burnout amongst health care professionals caring for COVID-19 patients in the Intensive Care Unit (ICU) of a Welsh hospital. The response rate was 79%. Nurses and other staf…
View article: Producing three-dimensional printed models of the hepatobiliary system from computed tomography imaging data
Producing three-dimensional printed models of the hepatobiliary system from computed tomography imaging data Open
Introduction Macroscopic anatomy has traditionally been taught using cadaveric material, lectures and a variety of additional resources including online modules and anatomical models. Traditional plastic models are effective educational to…
View article: The articularis genu muscle and its relevance in oncological surgical margins
The articularis genu muscle and its relevance in oncological surgical margins Open
Aims The aticularis genu (AG) is the least substantial and deepest muscle of the anterior compartment of the thigh and of uncertain significance. The aim of the study was to describe the anatomy of AG in cadaveric specimens, to characteriz…
View article: Producing 3D printed high‐fidelity retroperitoneal models from in vivo patient data: The Oxford Method
Producing 3D printed high‐fidelity retroperitoneal models from in vivo patient data: The Oxford Method Open
Macroscopic anatomy has traditionally been taught using cadaveric material, lectures and a variable amount of additional resources such as online modules. Anatomical models have also been used to assist in teaching. Of these, traditional p…
View article: Innovating surgical practice and policy: lessons learnt from the second Oxford Surgical Innovation Conference
Innovating surgical practice and policy: lessons learnt from the second Oxford Surgical Innovation Conference Open
The section on changes in training from the Future in Surgery Report by the Royal College of Surgeons of England outlined key ideas for improving surgical training in the future. These ideas included the use of augmented reality, virtual r…
View article: Modernising Anatomy Teaching: Which Resources Do Students Rely On?
Modernising Anatomy Teaching: Which Resources Do Students Rely On? Open
The way in which we learn anatomy has changed exponentially over the decades and students now have access to lecture notes, textbooks, computer-assisted programmes, and a wide variety of internet based information. This study explored whic…
View article: A PILOT STUDY OF THE ACCEPTANCE AND TOLERABILITY OF TUMOUR TREATING FIELDS IN ADULT GLIOBLASTOMA PATIENTS
A PILOT STUDY OF THE ACCEPTANCE AND TOLERABILITY OF TUMOUR TREATING FIELDS IN ADULT GLIOBLASTOMA PATIENTS Open
BACKGROUND: Tumour treating fields are a novel anticancer treatment that uses alternate electrical fields to disrupt cell division. It has been shown in a randomized controlled trial to significantly improve survival in patients with Gliob…
Experimental Validation of Graph-Based Hierarchical Control for Thermal Management Open
This paper proposes and experimentally validates a hierarchical control framework for fluid flow systems performing thermal management in mobile energy platforms. A graph-based modeling approach derived from the conservation of mass and en…
View article: Ketogenic therapy:the experience of adult brain tumour patients supported by Matthews Friends
Ketogenic therapy:the experience of adult brain tumour patients supported by Matthews Friends Open
BACKGROUND: There is increasing interest in ketogenic diet (KD) as an adjuvant to standard care (surgery, chemo-radiation, dexamethasone and anticonvulsant medication) for brain tumour and associated symptom management, within the brain tu…
View article: Dynamical Graph Models of Aircraft Electrical, Thermal, and Turbomachinery Components
Dynamical Graph Models of Aircraft Electrical, Thermal, and Turbomachinery Components Open
The current trend of electrification in modern aircraft has driven a need to design and control onboard power systems that are capable of meeting strict performance requirements while maximizing overall system efficiency. Model-based contr…
View article: A framework for the control of electro-thermal aircraft power systems
A framework for the control of electro-thermal aircraft power systems Open
This dissertation presents a hierarchical controller framework that utilizes model predictive controllers at multiple time scales in order to manage the operation of aircraft power systems. With current and next generation aircraft replaci…
View article: Data for the Oxford Abdominal Aortic Aneurysm Study international survey of vascular surgery professionals
Data for the Oxford Abdominal Aortic Aneurysm Study international survey of vascular surgery professionals Open
As part of the Oxford Abdominal Aortic Aneurysm (OxAAA) Study, we conducted an international survey of vascular surgery professionals. One aspect of the survey is as published in the International Journal of Cardiology: "International Opin…
View article: CD4:CD8 Ratio and CD8 Count as Prognostic Markers for Mortality in Human Immunodeficiency Virus–Infected Patients on Antiretroviral Therapy: The Antiretroviral Therapy Cohort Collaboration (ART-CC)
CD4:CD8 Ratio and CD8 Count as Prognostic Markers for Mortality in Human Immunodeficiency Virus–Infected Patients on Antiretroviral Therapy: The Antiretroviral Therapy Cohort Collaboration (ART-CC) Open
In this large cohort collaboration, the magnitude of adjusted associations of CD4:CD8 ratio or CD8 count with mortality was too small for them to be useful as independent prognostic markers in virally suppressed patients on ART.
View article: Flow Mediated Dilatation as a Biomarker in Vascular Surgery Research
Flow Mediated Dilatation as a Biomarker in Vascular Surgery Research Open
Endothelial dysfunction is one of the hallmarks of atherogenesis, and correlates with many cardiovascular risk factors. One of the features of endothelial dysfunction is the loss of nitric oxide (NO) bioavailability, resulting in derangeme…
View article: Implementation of ipilimumab therapy in a private practice oncology group: overcoming start-up and reimbursement issues related to expensive new cancer drugs
Implementation of ipilimumab therapy in a private practice oncology group: overcoming start-up and reimbursement issues related to expensive new cancer drugs Open
How We Do ItImplementation of ipilimumab therapy in a private practice oncology group: overcoming start-up and reimbursement issues related to expensive new cancer drugs