Merel Dagher
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View article: Safety in treatment: Classical pharmacotherapeutics and new avenues for addressing maternal depression and anxiety during pregnancy
Safety in treatment: Classical pharmacotherapeutics and new avenues for addressing maternal depression and anxiety during pregnancy Open
We aimed to review clinical research on the safety profiles of antidepressant drugs and associations with maternal depression and neonatal outcomes. We focused on neuroendocrine changes during pregnancy and their effects on antidepressant …
View article: Neuroinflammation drives sex-dependent effects on pain and negative affect in a murine model of repeated mild traumatic brain injury
Neuroinflammation drives sex-dependent effects on pain and negative affect in a murine model of repeated mild traumatic brain injury Open
The Center for Disease Control and Prevention estimates that 75% of reported cases of traumatic brain injury (TBI) are mild, where chronic pain and depression are 2 of the most common symptoms. In this study, we used a murine model of repe…
View article: Optogenetic Stimulation of Midbrain Dopamine Neurons Produces Striatal Serotonin Release
Optogenetic Stimulation of Midbrain Dopamine Neurons Produces Striatal Serotonin Release Open
Targeting neurons with light-driven opsins is widely used to investigate cell-specific responses. We transfected midbrain dopamine neurons with the excitatory opsin Chrimson. Extracellular basal and stimulated neurotransmitter levels in th…
View article: Simultaneous serotonin and dopamine monitoring across timescales by rapid pulse voltammetry with partial least squares regression
Simultaneous serotonin and dopamine monitoring across timescales by rapid pulse voltammetry with partial least squares regression Open