Explanipedia

Areal differences in the utilization of endovascular therapy for acute ischemic stroke Open

Ulla Junttola, Siiri Hietanen, Sanna Lahtinen, Juha-Matti Isokangas, Lasse Raatiniemi , et al. · 2025

Endovascular therapy (EVT) is standard care for acute ischemic stroke due to large vessel occlusion, but its availability is limited in areas with long distances. It has also been demonstrated that there are differences in the utilization …

Spinal Anaesthesia Versus General Anaesthesia for Patients With Tibia Shaft Fractures—A Randomized Controlled Study Open

Pasi Lehto, Merja Vakkala, Iikka Lantto, Pasi Ohtonen, Janne Liisanantti , et al. · 2025

Background Concerns about the delayed diagnosis of acute compartment syndrome have led to recommendations favouring general anaesthesia over spinal anaesthesia in surgeries for diaphyseal tibia fractures. However, there is a lack of suppor…

Socio-economic factors and rural-urban differences in patients undergoing emergency laparotomy Open

Anne Pouke, Aura T. Ylimartimo, Juho Nurkkala, Sanna Lahtinen, Marjo Koskela , et al. · 2024

Background: Emergency laparotomy (EL) is a common surgical procedure with high rates of mortality and complications. Socio-economic circumstances and regional differences have an influence on the utilization of care and outcomes in many di…

Reliability of Bioreactance and Pulse-Power Analysis in Measuring Cardiac Index During Open Abdominal Aortic Surgery Open

Heikki Pekka Oskari Ronkainen, Laura Anneli Ylikauma, Mari Johanna Pohjola, Pasi Ohtonen, Tiina Erkinaro , et al. · 2024

The CI measurements achieved with Starling SV and LiDCOrapid were not interchangeable with TDCO, and the ability to track changes in CI was poor. These results do not support the use of either study device in monitoring CI during open AA s…

Quality of Life After Endovascular Thrombectomy for Acute Ischemic Stroke in Northern Finland Open

Ulla Junttola, Janne Liisanantti, Juha‐Matti Isokangas, Timo Kaakinen, Merja Vakkala , et al. · 2024

Objectives: Endovascular thrombectomy has demonstrated a major therapeutic improvement in the treatment of acute ischemic stroke. The benefit of endovascular thrombectomy is commonly reported by determining the functional outcome using the…

The effect of tourniquet use on postoperative opioid consumption after ankle fracture surgery – a retrospective cohort study Open

Pasi Lehto, Tero Kortekangas, Merja Vakkala, Pasi Ohtonen, Emma‐Sofia Nyman , et al. · 2023

Objectives A pneumatic tourniquet is often used during ankle fracture surgery to reduce bleeding and enhance the visibility of the surgical field. Tourniquet use causes both mechanical and ischemic pain. The main purpose of this study was …

Blood–Brain Barrier Disruption (BBBD)-Based Immunochemotherapy for Primary Central Nervous System Lymphoma (PCNSL), Early Results of a Phase II Study Open

Hanne Kuitunen, Aino Rönkä, Eila Sonkajärvi, Juha‐Matti Isokangas, Marja Pyörälä , et al. · 2023

Primary central nervous system lymphoma is a rare but aggressive brain malignancy. It is associated with poor prognosis even with the current standard of care. The aim of this study was to evaluate the effect and tolerability of blood–brai…

Changes in transcranial near‐infrared spectroscopy values reflect changes in cardiac index during cardiac surgery Open

Katriina M. Lanning, Laura Anneli Ylikauma, Tiina Erkinaro, Pasi Ohtonen, Merja Vakkala , et al. · 2023

To determine whether changes in transcranial near‐infrared spectroscopy (NIRS) values reflect changes in cardiac index (CI) in adult cardiac surgical patients. Single‐center prospective post hoc analysis. University hospital. One hundred a…

Reliability of bioreactance and pulse power analysis in measuring cardiac index during cytoreductive abdominal surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) Open

Laura Anneli Ylikauma, Mari Tuovila, Pasi Ohtonen, Tiina Erkinaro, Merja Vakkala , et al. · 2023

RELIABILITY OF BIOREACTANCE AND PULSE POWER ANALYSIS IN MEASURING CARDIAC INDEX DURING OPEN ABDOMINAL AORTIC SURGERY Open

Hanna Ronkainen, Laura Anneli Ylikauma, Pasi Ohtonen, Tiina Erkinaro, Merja Vakkala , et al. · 2022

Long-term mortality after endovascular thrombectomy for stroke Open

Ulla Junttola, Sanna Lahtinen, Juha‐Matti Isokangas, Siiri Hietanen, Merja Vakkala , et al. · 2022

Postoperative Complications and Outcome After Emergency Laparotomy: A Retrospective Study Open

Aura T. Ylimartimo, Juho Nurkkala, Marjo Koskela, Sanna Lahtinen, Timo Kaakinen , et al. · 2022

Background Emergency laparotomy (EL) is a common urgent surgical procedure with high risk for postoperative complications. Complications impair the prognosis and prolong the hospital stay. This study explored the incidence and distribution…

Long-term Outcomes After Emergency Laparotomy: a Retrospective Study Open

Aura T. Ylimartimo, Sanna Lahtinen, Juho Nurkkala, Marjo Koskela, Timo Kaakinen , et al. · 2022

Outcomes in patients requiring intensive care unit (<span>ICU</span>) admission after emergency laparotomy: A retrospective study Open

Aura T. Ylimartimo, Marjo Koskela, Sanna Lahtinen, Timo Kaakinen, Merja Vakkala , et al. · 2022

Purpose Outcomes after emergency laparotomy (EL) are poor. These patients are often admitted to an intensive care unit (ICU). This study explored outcomes in patients who were admitted to an ICU within 48 h after EL. Materials and Methods …

Articles to Appear in Future Issues Open

Cengiz Kaya, Burhan Dost, Ozgur Dokmeci, Semih Murat, Deni̇z Karakaya , et al. · 2022

Developing a supervised machine learning model for predicting perioperative acute kidney injury in arthroplasty patients Open

Okke Nikkinen, Timo Kolehmainen, Toni Aaltonen, Elias Jämsä, Seppo Alahuhta , et al. · 2022

Reliability of Bioreactance and Pulse-Power Analysis in Measuring Cardiac Index in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass Open

Laura Anneli Ylikauma, Katriina M. Lanning, Tiina Erkinaro, Pasi Ohtonen, Merja Vakkala , et al. · 2021

Accuracy, Precision, and Trending Ability of Perioperative Central Venous Oxygen Saturation Compared to Mixed Venous Oxygen Saturation in Unselected Cardiac Surgical Patients Open

Katriina M. Lanning, Tiina Erkinaro, Pasi Ohtonen, Merja Vakkala, Janne Liisanantti , et al. · 2021

Medical complications and outcome after endovascular therapy for acute ischemic stroke Open

Ulla Junttola, Sanna Lahtinen, Janne Liisanantti, Merja Vakkala, Timo Kaakinen , et al. · 2021

Medical complications are common among unselected stroke patients undergoing EVT. Both comorbidity and stroke severity have an influence on medical complications. Early recognition of complications is essential, because vast majority of pa…

Bioreactance and fourth-generation pulse contour methods in monitoring cardiac index during off-pump coronary artery bypass surgery Open

Laura Anneli Ylikauma, Pasi Ohtonen, Tiina Erkinaro, Merja Vakkala, Janne Liisanantti , et al. · 2021

Difference in postoperative opioid consumption after spinal versus general anaesthesia for ankle fracture surgery—A retrospective cohort study Open

Pasi Lehto, Merja Vakkala, Seppo Alahuhta, Janne Liisanantti, Tero Kortekangas , et al. · 2021

Background Surgical treatment of ankle fracture is associated with significant pain and high postoperative opioid consumption. The anaesthesia method may affect early postoperative pain. The main objective of the study was to compare posto…

Perioperative acute kidney injury and urine output in lower limb arthroplasties Open

Okke Nikkinen, Elias Jämsä, Toni Aaltonen, Seppo Alahuhta, Pasi Ohtonen , et al. · 2021

Background This study aimed to evaluate the occurrence and perioperative risk factors of acute kidney injury (AKI) in primary elective hip and knee and emergency hip arthroplasty patients. We also aimed to assess the effect of urine output…

Nutrition delivery after emergency laparotomy in surgical ward: a retrospective cohort study Open

Juho Nurkkala, Sanna Lahtinen, Aura T. Ylimartimo, Timo Kaakinen, Merja Vakkala , et al. · 2021

Purpose Adequate nutrition after major abdominal surgery is associated with less postoperative complications and shorter hospital length of stay (LOS) after elective procedures, but there is a lack of studies focusing on the adequacy of nu…

Causes of nutrition deficit during immediate postoperative period after free flap surgery for cancer of the head and neck Open

Juho Nurkkala, Sanna Lahtinen, Timo Kaakinen, Merja Vakkala, Janne Liisanantti · 2020

Brain tight junction protein expression in sepsis in an autopsy series Open

Kristo Erikson, Hannu Tuominen, Merja Vakkala, Janne Liisanantti, Tuomo J. Karttunen , et al. · 2020

Background Neuroinflammation often develops in sepsis along with increasing permeability of the blood-brain barrier (BBB), which leads to septic encephalopathy. The barrier is formed by tight junction structures between the cerebral endoth…

Single dose epidural hydromorphone in labour pain: maternal pharmacokinetics and neonatal exposure Open

Terhi Puhto, Merja Kokki, Henriikka Hakomäki, Michael Spalding, Teemu Gunnar , et al. · 2020

Hydromorfonin ekvianalgeettiset annokset Open

Terhi Puhto, Voitto Järvimäki, Merja Vakkala, Eero Vuorinen · 2018

Incidence and predictive factors of spinal cord stimulation treatment after lumbar spine surgery Open

Merja Vakkala, Voitto Järvimäki, Hannu Kautiainen, Maija Haanpää, Seppo Alahuhta · 2017

In our region, the SCS treatment is used only for very serious pain conditions. Waiting time is too long and it may be the reason why this treatment option is not offered to all candidates.

Depressive symptoms are associated with poor outcome for lumbar spine surgery Open

Voitto Järvimäki, Hannu Kautiainen, Maija Haanpää, Hannu Koponen, Michael Spalding , et al. · 2016

Background and aims The symptoms of pain and depression often present concomitantly, but little is known as to how the different subtypes of depression affect surgical outcome. The aim of this study was to determine whether there is a diff…

Respiratory Effort Belts in Postoperative Respiratory Monitoring: Pilot Study with Different Patients Open

Tiina M. Seppänen, Olli‐Pekka Alho, Merja Vakkala, Seppo Alahuhta, Tapio Seppänen · 2016

Respiratory complications are common in patients after the general anaesthesia. Respiratory depression often occurs in association with postoperative opioid analgesia. Currently, there is a need for a continuous non-invasive respiratory mo…

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