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View article: Unhealthy diet quality as a clinical phenotype in bipolar disorder: A potential treatment target for improved mood and metabolic outcomes
Unhealthy diet quality as a clinical phenotype in bipolar disorder: A potential treatment target for improved mood and metabolic outcomes Open
These findings highlight the importance of investigating diet quality as a potential therapeutic target in the management of BD to improve mood outcomes and mitigate risk of metabolic disorders.
View article: Neural signatures of bipolar disorder subtypes: A comprehensive systematic review of neuroimaging studies
Neural signatures of bipolar disorder subtypes: A comprehensive systematic review of neuroimaging studies Open
The neurobiological mechanisms differentiating bipolar disorder type I (BD-I) from type II (BD-II) remain poorly understood. A comprehensive synthesis systematically comparing neuroimaging findings between BD subtypes is lacking. We conduc…
View article: A Cross‐Sectional Analysis of Social Determinants of Health in Bipolar Disorder: Exploring Gender‐Related Differences
A Cross‐Sectional Analysis of Social Determinants of Health in Bipolar Disorder: Exploring Gender‐Related Differences Open
Objectives To explore the clinical impact of social determinants of health (SDoH) stress in bipolar disorder (BD) course of illness and to explore potential gender differences in SDoH stress endorsement. Methods 2280 individuals living wit…
View article: Sodium-Glucose Cotransporter 2 Inhibitors for Lithium-Associated Kidney Dysfunction in Mood Disorders: A Real-World Historical Cohort Study
Sodium-Glucose Cotransporter 2 Inhibitors for Lithium-Associated Kidney Dysfunction in Mood Disorders: A Real-World Historical Cohort Study Open
Introduction Sodium-glucose cotransporter-2 inhibitors (SGLT2i), initially developed for type 2 diabetes, have shown promise in improving renal outcomes in patients with and without diabetes. However, their effect on lithium-associated kid…
View article: Prevalence of Dermatologic Side Effects of Mood Stabilizers in Bipolar Disorder: A Systematic Review and A Meta-Analysis
Prevalence of Dermatologic Side Effects of Mood Stabilizers in Bipolar Disorder: A Systematic Review and A Meta-Analysis Open
Introduction Bipolar disorder (BD) is a chronic illness affecting approximately 2-3% adults worldwide. Mood stabilizers, such as lithium, valproate, carbamazepine, and lamotrigine are mainstays of the treatment. Despite their benefits, moo…
View article: Psychiatric Association of Turkey, Scientific Section for Mood Disorders, Depression Treatment Guideline – I: Introduction, Terminology, Core Concepts, Assessment Methods
Psychiatric Association of Turkey, Scientific Section for Mood Disorders, Depression Treatment Guideline – I: Introduction, Terminology, Core Concepts, Assessment Methods Open
Major depressive disorder (MDD), with its heterogeneous nature and variable course, poses significant challenges for clinicians in treatment planning and clinical decision-making. These challenges are further compounded by the rapid emerge…
View article: Measuring the exposome in bipolar disorder
Measuring the exposome in bipolar disorder Open
Although bipolar disorder is highly heritable, the identified genetic variants explain only a small portion of phenotypic variation and overall disease risk. Contemporaries of Kraepelin delineate environmental exposure to disease, in part,…
View article: Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder
Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder Open
There is increasing interest in individualizing treatment selection for more than 25 regulatory approved treatments for major depressive disorder (MDD). Despite an inconclusive efficacy evidence base, antidepressants (ADs) are prescribed f…
View article: Factors associated with suicide attempts in the antecedent illness trajectory of bipolar disorder and schizophrenia
Factors associated with suicide attempts in the antecedent illness trajectory of bipolar disorder and schizophrenia Open
Background Factors associated with suicide attempts during the antecedent illness trajectory of bipolar disorder (BD) and schizophrenia (SZ) are poorly understood. Methods Utilizing the Rochester Epidemiology Project, individuals born afte…
View article: Racial differences in pathways to care preceding first episode mania or psychosis: a historical cohort prodromal study
Racial differences in pathways to care preceding first episode mania or psychosis: a historical cohort prodromal study Open
Background There is evidence suggesting racial disparities in diagnosis and treatment in bipolar disorder (BD) and schizophrenia (SZ). The purpose of this study is to compare psychiatric diagnoses and psychotropic use preceding a first epi…
View article: Pharmacogenomic Overlap Between Antidepressant Treatment Response in Major Depression & Antidepressant Associated Treatment Emergent Mania in Bipolar Disorder
Pharmacogenomic Overlap Between Antidepressant Treatment Response in Major Depression & Antidepressant Associated Treatment Emergent Mania in Bipolar Disorder Open
There is increasing interest in individualizing treatment selection for more than 25 regulatory approved treatments for major depressive disorder (MDD). Despite an inconclusive efficacy evidence base, antidepressants (ADs) are prescribed f…
View article: Long-Term Lithium Therapy and Thyroid Disorders in Bipolar Disorder: A Historical Cohort Study
Long-Term Lithium Therapy and Thyroid Disorders in Bipolar Disorder: A Historical Cohort Study Open
Lithium has been a cornerstone treatment for bipolar disorder (BD). Despite descriptions in the literature regarding associations between long-term lithium therapy (LTLT) and development of a thyroid disorder (overt/subclinical hypo/hypert…
View article: Neuropsychiatric outcomes of patients with encephalitis: A case series with long-term follow-up
Neuropsychiatric outcomes of patients with encephalitis: A case series with long-term follow-up Open
Objective: The long-term course of neuropsychiatric, cognitive, and behavioral symptoms that develop after encephalitis has not been studied adequately. We aimed to investigate the progression of these symptoms in a case series of patients…
View article: The Relationship of the Impulsivity and Decision-Making Behavior with Social Cognitive Skills in Borderline Personality Disorder
The Relationship of the Impulsivity and Decision-Making Behavior with Social Cognitive Skills in Borderline Personality Disorder Open
As a result of our study, it was concluded that individuals with BPD have minimal difficulty in inhibiting inappropriate response, and this difficulty is related to making disadvantageous choices in decision-making behavior. While BPD grou…
View article: Treatment-Resistant Bipolar Depression: Therapeutic Trends, Challenges and Future Directions
Treatment-Resistant Bipolar Depression: Therapeutic Trends, Challenges and Future Directions Open
Evidence on current treatment modalities for TRBD is limited with low efficacy. More research is needed for successful treatment of TRBD. Effective therapies and innovative approaches to treatment are being investigated and could show prom…
View article: SOCIAL SUPPORT PROMOTES MENTAL HEALTH DURING THE COVID-19 OUTBREAK: A CROSS-SECTIONAL STUDY FROM TURKEY
SOCIAL SUPPORT PROMOTES MENTAL HEALTH DURING THE COVID-19 OUTBREAK: A CROSS-SECTIONAL STUDY FROM TURKEY Open
Vulnerable groups should be identified and protected to reduce adverse psychiatric outcomes of COVID-19. Besides, further strategies should be provided to maintain protective factors, such as social support, under stressful conditions.
View article: Psychological reactions of Turkish healthcare workers during Covid-19 outbreak: The impact of stigmatization
Psychological reactions of Turkish healthcare workers during Covid-19 outbreak: The impact of stigmatization Open
Our study shows that healthcare workers are at risk of developing psychological disturbances during infectious outbreaks. To minimize the psychological impact, additional risk factors such as having a previous psychiatric disorder, working…