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View article: A Clinical Medication Review Focused on Deprescribing in Older Patients With Hyperpolypharmacy: A Mixed‐Methods Feasibility Study
A Clinical Medication Review Focused on Deprescribing in Older Patients With Hyperpolypharmacy: A Mixed‐Methods Feasibility Study Open
To address challenges in deprescribing, we investigated the feasibility of an intervention consisting of a clinical medication review (CMR) focused on deprescribing, supported by a training programme for healthcare providers (HCPs) among o…
View article: Patients' perspectives and experiences regarding medication reviews: A cross-sectional survey study
Patients' perspectives and experiences regarding medication reviews: A cross-sectional survey study Open
Most patients valued medication reviews, yet only half were aware of their existence. Generally, levels of polypharmacy hardly impacted patient perspectives. Based on patients' experiences, shared decision-making, follow-ups, and multidisc…
View article: Patients' Attitudes Towards Deprescribing Differ Across Specific Cardiovascular and Diabetes Medication: A Survey Study Assessing Within‐Patient Differences
Patients' Attitudes Towards Deprescribing Differ Across Specific Cardiovascular and Diabetes Medication: A Survey Study Assessing Within‐Patient Differences Open
Background Knowing whether patients' attitudes towards deprescribing differ by medication is important for implementing deprescribing in practice. Objective To assess whether there are within‐patient differences in attitudes towards depres…
View article: Patient counselling on opioids by pharmacy technicians: A mixed-method study to explore facilitators and barriers
Patient counselling on opioids by pharmacy technicians: A mixed-method study to explore facilitators and barriers Open
This research focuses on an underexplored group involved in patients' opioid management, crucial for designing effective interventions, as PTs frequently have direct patient contact.
View article: Pharmacists’ perspectives on potential pharmacist prescribing: a nationwide survey in the Netherlands
Pharmacists’ perspectives on potential pharmacist prescribing: a nationwide survey in the Netherlands Open
Background Pharmacist prescribing legislation aims to enhance healthcare quality and accessibility. However, in many countries, like the Netherlands, it has not yet been legally established. Aim To investigate pharmacists’ perspectives on …
View article: Factors influencing the implementation of the CombiConsultation in Dutch clinical practice: a mixed-methods study
Factors influencing the implementation of the CombiConsultation in Dutch clinical practice: a mixed-methods study Open
Objective The CombiConsultation is an innovative concise clinical pharmacy service by the community pharmacist for patients with a chronic condition. We aimed to identify relevant factors influencing the implementation of the CombiConsulta…
View article: Pharmacists’ current and potential prescribing roles in primary care in the Netherlands: a case study
Pharmacists’ current and potential prescribing roles in primary care in the Netherlands: a case study Open
In some countries, pharmacists have obtained prescribing rights to improve quality and accessibility of care and reduce physician workload. This case study explored pharmacists' current roles in and potential for prescribing in primary car…
View article: Community pharmacists’ attitudes towards checking prescriptions: a cross-sectional survey
Community pharmacists’ attitudes towards checking prescriptions: a cross-sectional survey Open
Background The final prescription check is a mandatory but time-consuming process in Dutch community pharmacies. A safer dispensing process may have made the final prescription check obsolete. Objective To describe the final prescription c…
View article: General practitioners' and community pharmacists' beliefs and practices on opioids for non‐malignant pain
General practitioners' and community pharmacists' beliefs and practices on opioids for non‐malignant pain Open
Background In Europe, opioid use has surged, largely due to prescriptions for chronic non‐malignant pain (CNMP). General practitioners (GPs) and community pharmacists (CPs) play a major role in opioid prescribing for non‐malignant pain. Ex…
View article: Patient perspectives on primary care providers role in long-term opioid therapy
Patient perspectives on primary care providers role in long-term opioid therapy Open
Introduction: Over the past decade, long-term use of prescription opioids for chronic non-cancer pain (CNCP) has risen globally despite the associated risks. The majority of opioid users receive their first prescription in primary care. Ai…
View article: Process evaluation of a pharmacist‐led intervention aimed at deprescribing and appropriate use of cardiometabolic medication among adult people with type 2 diabetes
Process evaluation of a pharmacist‐led intervention aimed at deprescribing and appropriate use of cardiometabolic medication among adult people with type 2 diabetes Open
Background A quasi‐experimental study investigated a pharmacist‐led intervention aimed at deprescribing and medication management among adult patients with type 2 diabetes at risk of hypoglycaemia. Objective This study aimed to evaluate th…
View article: Barriers and facilitators for the implementation of the CombiConsultation by general practitioners, pharmacists and practice nurses: a qualitative interview study
Barriers and facilitators for the implementation of the CombiConsultation by general practitioners, pharmacists and practice nurses: a qualitative interview study Open
Background The CombiConsultation is a consultation with the pharmacist for patients with a chronic condition, aligned with the periodic consultation with the practice nurse or general practitioner. Implementation requires adjustments in th…
View article: Pragmatic Delphi study aimed at determining practical components for a tool designed to assist Dutch primary care-givers in opioid deprescribing for non-cancer pain
Pragmatic Delphi study aimed at determining practical components for a tool designed to assist Dutch primary care-givers in opioid deprescribing for non-cancer pain Open
Background Over the past decades, opioid prescriptions have increased in the Netherlands. The Dutch general practitioners’ guideline on pain was recently updated and now aims to reduce opioid prescriptions and high-risk opioid use for non-…
View article: Communication skills-based training about medication switch encounters: mixed-method study on pharmacy staff and patients’ experiences
Communication skills-based training about medication switch encounters: mixed-method study on pharmacy staff and patients’ experiences Open
Background. Non-medical medication switches can lead to difficult conversations. To support pharmacy staff, a communication training has been developed based on two strategies: (1) 'positive message framing' to emphasize positive elements …
View article: The CombiConsultation for patients with diabetes, COPD and cardiovascular diseases: Evaluation of interventions and personal health-related goals
The CombiConsultation for patients with diabetes, COPD and cardiovascular diseases: Evaluation of interventions and personal health-related goals Open
The CombiConsultation can be used as a compact health service contributing to safe and effective use of medication for patients with diabetes, COPD and/or (at risk of) CVD, also in patients under 65 or with less than 5 medications in use. …
View article: Feasibility of Community Pharmacist-Initiated and Point-of-Care CYP2C19 Genotype-Guided De-Escalation of Oral P2Y12 Inhibitors
Feasibility of Community Pharmacist-Initiated and Point-of-Care CYP2C19 Genotype-Guided De-Escalation of Oral P2Y12 Inhibitors Open
Tailoring antiplatelet therapy based on CYP2C19 pharmacogenetic (PGx) testing can improve cardiovascular outcomes and potentially reduce healthcare costs in patients on a P2Y12-inhibitor regime with prasugrel or ticagrelor. However, ubiqui…
View article: Process evaluation of a pharmacist-led intervention aimed at deprescribing and appropriate use of cardiometabolic medication among people with type 2 diabetes
Process evaluation of a pharmacist-led intervention aimed at deprescribing and appropriate use of cardiometabolic medication among people with type 2 diabetes Open
Background: A quasi-experimental study investigated a pharmacist-led intervention aimed at deprescribing among patients with type 2 diabetes at risk of hypoglycaemia. Objective: To evaluate the process of implementing the intervention in p…
View article: Predictors for inappropriate proton pump inhibitor use: observational study in primary care
Predictors for inappropriate proton pump inhibitor use: observational study in primary care Open
Background Proton pump inhibitor (PPI) indications are limited to gastrointestinal disorders and ulcer prophylaxis. However, PPIs are among the most frequently prescribed drugs. Aim To evaluate the appropriateness of PPI prescriptions and …
View article: Barriers and Enablers of Older Patients to Deprescribing of Cardiometabolic Medication: A Focus Group Study
Barriers and Enablers of Older Patients to Deprescribing of Cardiometabolic Medication: A Focus Group Study Open
Fears, beliefs, and experiences regarding using and stopping medication as well as trust in the HCP influence willingness to have medication deprescribed. Attitudes towards medication in general do not necessarily translate into willingnes…