Ming Zhang
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View article: The effect of VEGF, ET-1 and TGF-β1 levels in peritoneal dialysis effluent on peritoneal solute transport function
The effect of VEGF, ET-1 and TGF-β1 levels in peritoneal dialysis effluent on peritoneal solute transport function Open
Objective This study aims to assess the impact of Vascular endothelial growth factor (VEGF), Endothelin-1 (ET-1), and Transforming growth factor-β1 (TGF-β1) levels in peritoneal dialysis effluent on peritoneal solute transport function. Me…
View article: Effects of Novel Mutations in the LEPR Gene on Litter Size in Gobi Short Tail Sheep and Sonid Sheep
Effects of Novel Mutations in the LEPR Gene on Litter Size in Gobi Short Tail Sheep and Sonid Sheep Open
Increasing the litter size in sheep is a primary objective in breeding programs, driving sustained interest in identifying candidate functional genes and molecular markers associated with fecundity. The known FecD mutation in the LEPR gene…
View article: Chemotherapy plus Nimotuzumab and Immunotherapy as Induction Regime Followed by Sequential Chemoradiotherapy and Consolidation Immunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma: A Prospective, Single-Arm, Open-Label, Phase II Trial
Chemotherapy plus Nimotuzumab and Immunotherapy as Induction Regime Followed by Sequential Chemoradiotherapy and Consolidation Immunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma: A Prospective, Single-Arm, Open-Label, Phase II Trial Open
View article: Dynamic Chunking and Selection for Reading Comprehension of Ultra-Long Context in Large Language Models
Dynamic Chunking and Selection for Reading Comprehension of Ultra-Long Context in Large Language Models Open
Large language models (LLMs) often struggle to accurately read and comprehend extremely long texts. Current methods for improvement typically rely on splitting long contexts into fixed-length chunks. However, fixed truncation risks separat…
View article: Comparative Transcriptomic Analysis Between High- and Low-Growth-Rate Meat-Type Rabbits Reveals Key Pathways Associated with Muscle Development
Comparative Transcriptomic Analysis Between High- and Low-Growth-Rate Meat-Type Rabbits Reveals Key Pathways Associated with Muscle Development Open
Rabbit meat constitutes a high-protein, low-fat nutritional resource demonstrating rising consumption, particularly within the Asia-Pacific region. Consequently, muscle growth and developmental pattern in meat rabbits represent critical ec…
View article: A Systematic Review of Finite Element Analysis in Running Footwear Biomechanics: Insights for Running-Related Musculoskeletal Injuries
A Systematic Review of Finite Element Analysis in Running Footwear Biomechanics: Insights for Running-Related Musculoskeletal Injuries Open
This study presented a systematic review of recent advancements in the application of finite element (FE) methods to running and running shoe biomechanics. It focused on outlining the general approach to build foot-running shoe FE models, …
View article: Periostin-mediated activation of NF-κB signaling promotes tumor progression and chemoresistance in glioblastoma
Periostin-mediated activation of NF-κB signaling promotes tumor progression and chemoresistance in glioblastoma Open
View article: Reduction in Liver Cancer Risk by Quercetin via Modulation of Urate Levels: Insights from Drug-Target Mendelian Randomization
Reduction in Liver Cancer Risk by Quercetin via Modulation of Urate Levels: Insights from Drug-Target Mendelian Randomization Open
Background: Quercetin, a dietary flavonoid and a widely used supplement, has hepatoprotective properties. Given its urate-lowering effects and epidemiological evidence linking elevated serum urate levels to liver cancer risk, we tested whe…
View article: Cluster-guided Contrastive Class-imbalanced Graph Classification
Cluster-guided Contrastive Class-imbalanced Graph Classification Open
This paper studies the problem of class-imbalanced graph classification, which aims at effectively classifying the graph categories in scenarios with imbalanced class distributions. While graph neural networks (GNNs) have achieved remarkab…
View article: Soil biofilm and restoration of degraded soil
Soil biofilm and restoration of degraded soil Open
View article: Context Aware Multimodal Fusion YOLOv5 Framework for Pedestrian Detection under IoT Environment
Context Aware Multimodal Fusion YOLOv5 Framework for Pedestrian Detection under IoT Environment Open
Pedestrian detection based on deep networks has become a research hotspot in the field of computer vision. With the rapid development of the Internet of Things (IoT) and autonomous driving technology, the deployment of pedestrian detection…
View article: Effects of 1,3‐Dioleoyl‐2‐palmitoylglycerol on Intestine Structural and Functional Development in Early Life
Effects of 1,3‐Dioleoyl‐2‐palmitoylglycerol on Intestine Structural and Functional Development in Early Life Open
1,3‐Dioleoyl‐2‐palmitoyl‐glycerol (OPO) is a specific triglyceride in human breast milk, and it has been added to infant formula to mimic human breast milk fat. Existing studies only focused on its effects on fatty acid and calcium absorpt…
View article: The Comparison Transcriptome Between High and Low Growth Ratio of Meat-Type Rabbit Revealed the Primary Pathway Related to Muscle Development
The Comparison Transcriptome Between High and Low Growth Ratio of Meat-Type Rabbit Revealed the Primary Pathway Related to Muscle Development Open
Rabbit meat is a high-protein, low-fat health food with increasing consumption especially in the Asia-Pacific region. Therefore, muscle growth and development of meat rabbits are important economic traits. In order to reveal the primary si…
View article: Integrated metabolomic and transcriptomic analysis of the anthocyanin regulatory networks in Lagerstroemia indica petals
Integrated metabolomic and transcriptomic analysis of the anthocyanin regulatory networks in Lagerstroemia indica petals Open
Malvidin-3-O-glucoside and Peonidin-3-O-glucoside may contribute to variation of petal color in the three varieties. The upregulation of ANS, CHI, F3H, F3'H and UGT expression is involved in anthocyanin biosynthesis of the red pigmentation…
View article: Variants in BMP15 Gene Affect Promoter Activity and Litter Size in Gobi Short Tail and Ujimqin Sheep
Variants in BMP15 Gene Affect Promoter Activity and Litter Size in Gobi Short Tail and Ujimqin Sheep Open
Reproductive performance in sheep plays a crucial role in determining the economic efficiency of the industry, with increasing litter size being a key focus for genetic improvement. The BMP15 gene is widely recognized as a major gene influ…
View article: The m6A modification regulates the composition of myofiber types in chicken skeletal muscle
The m6A modification regulates the composition of myofiber types in chicken skeletal muscle Open
As a widespread epigenetic RNA modification, N6-methyladenosine (m6A) plays essential regulatory roles in multiple biological processes. However, its function in maintaining and modulating myofiber-type properties remains largely unknown. …
View article: Dynamic Chunking and Selection for Reading Comprehension of Ultra-Long Context in Large Language Models
Dynamic Chunking and Selection for Reading Comprehension of Ultra-Long Context in Large Language Models Open
View article: Malvidin-3-O-Glucoside Ameliorates the Development of Vascular Endothelial Dysfunction in Type 2 Diabetes Mellitus by Inhibiting Arginase 1 Expression
Malvidin-3-O-Glucoside Ameliorates the Development of Vascular Endothelial Dysfunction in Type 2 Diabetes Mellitus by Inhibiting Arginase 1 Expression Open
View article: Undeformed Chip Thickness Modeling in Euvag Considering Wheel Topography Evolution
Undeformed Chip Thickness Modeling in Euvag Considering Wheel Topography Evolution Open
View article: Multiomics analysis provides insights into musk secretion in muskrat and musk deer
Multiomics analysis provides insights into musk secretion in muskrat and musk deer Open
Background Musk, secreted by the musk gland of adult male musk-secreting mammals, holds significant pharmaceutical and cosmetic potential. However, understanding the molecular mechanisms of musk secretion remains limited, largely due to th…
View article: Study on Dense Phase Separation of Associated Gas with High Carbon Dioxide Content
Study on Dense Phase Separation of Associated Gas with High Carbon Dioxide Content Open
With the continuous exploitation of offshore natural gas, the content of CO2 produced gradually increases. It is not economical to separate more CO2 from natural gas after transportation, and more CO2 will aggravate the corrosion of pipeli…
View article: Cluster-guided Contrastive Class-imbalanced Graph Classification
Cluster-guided Contrastive Class-imbalanced Graph Classification Open
This paper studies the problem of class-imbalanced graph classification, which aims at effectively classifying the graph categories in scenarios with imbalanced class distributions. While graph neural networks (GNNs) have achieved remarkab…
View article: Development and validation of a machine learning-based model to predict survival in patients with cirrhosis after transjugular intrahepatic portosystemic shunt
Development and validation of a machine learning-based model to predict survival in patients with cirrhosis after transjugular intrahepatic portosystemic shunt Open
View article: Genome-wide association study of myofiber type composition traits in a yellow-feather broiler population
Genome-wide association study of myofiber type composition traits in a yellow-feather broiler population Open
View article: DCP1A, a MEK substrate, regulates the self-renewal and differentiation of mouse embryonic stem cells
DCP1A, a MEK substrate, regulates the self-renewal and differentiation of mouse embryonic stem cells Open
Mitogen-activated extracellular signal-regulated kinase (MEK) inhibitors are widely applied to maintain pluripotency, while prolonged MEK inhibition compromises the developmental potential of mouse embryonic stem cells (ESCs). To understan…
View article: Dynamic constitutive modelling and mullins effect of elastic‐porous metal rubber
Dynamic constitutive modelling and mullins effect of elastic‐porous metal rubber Open
Elastic‐porous metal rubber, commonly employed in dynamic environments, has received special attention nowadays. Utilization of equivalent metal rubber models in the finite element analysis becomes imperative because of the complexity of t…
View article: Longitudinal analysis of blood pressure control and influencing factors among 32 701 primary care hypertensive patients with or without diabetes: a prospective cohort study in Jianye District, China
Longitudinal analysis of blood pressure control and influencing factors among 32 701 primary care hypertensive patients with or without diabetes: a prospective cohort study in Jianye District, China Open
Background We aimed to explore the variation in blood pressure (BP) control in primary care hypertensive patients with or without diabetes, and investigate potential factors associated with inadequate BP control during follow-up. Methods P…
View article: Investigation of Influence of High Pressure on the Design of Deep-Water Horizontal Separator and Droplet Evolution
Investigation of Influence of High Pressure on the Design of Deep-Water Horizontal Separator and Droplet Evolution Open
Under deep-water high-pressure conditions, the multiphase flow characteristics within separators show significant differences compared to conventional separators. When designing subsea separators, it is crucial to consider the impact of pr…
View article: Transcriptomics integrated with targeted metabolomics reveals endogenous hormone changes in tuberous root expansion of Pueraria
Transcriptomics integrated with targeted metabolomics reveals endogenous hormone changes in tuberous root expansion of Pueraria Open
Our study has revealed how endogenous hormone regulation affects the expansion of "Gange No. 5" tuberous roots. These findings offer a theoretical foundation for improving the yield of PMT tuberous roots.
View article: Analysis of independent risk factors for hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with cirrhosis combined with diabetes
Analysis of independent risk factors for hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with cirrhosis combined with diabetes Open
Objective This study aimed to reveal the independent risk factors for overt hepatic encephalopathy (OHE) after transjugular intrahepatic portosystemic shunt (TIPS) in patients with decompensated cirrhosis complicated with diabetes. Patient…