Explanipedia

Guidelines for Modeling and Reporting Health Effects of Climate Change Mitigation Actions Open

Jeremy Hess, Nikhil Ranadive, Christopher Boyer, Lukasz Aleksandrowicz, Susan C. Anenberg , et al. · 2025

BACKGROUND: Modeling suggests that climate change mitigation actions can have substantial human health benefits that accrue quickly and locally. Documenting the benefits can help drive more ambitious and health-protective climate change mi…

The New York City Panel on Climate Change: 15 years of urban climate assessments Open

Prathap Ramamurthy, Luis Ortiz, Hayley Elszasz, Sheila R. Foster, Timon McPhearson , et al. · 2025

The International Panel on Climate Change’s assessment reports form the cornerstone for decarbonization and capacity building to combat the adverse effects of climate change at both international and national scales. However, the scope of …

Identifying optimal vaccination scenarios to reduce varicella zoster virus transmission and reactivation Open

Kevin Bakker, Marisa C. Eisenberg, Robert J. Woods, Micaela E. Martinez · 2022

Acquisition and Analysis of Crowd-Sensed Traffic Data at Multiple Spatial Scales Open

Jenni A. Shearston, Sebastian T. Rowland, Jemaleddin Cole, Steven N. Chillrud, Micaela E. Martinez , et al. · 2022

BACKGROUND/AIM: Measuring traffic activity at high spatial (e.g., street level) and temporal (e.g., sub-hourly) resolution is critical for studying traffic-related exposures and evaluating the efficacy of traffic-reduction interventions, y…

Cellular and transcriptional diversity over the course of human lactation Open

Sarah K. Nyquist, Patricia Gao, Tessa K. J. Haining, Michael R. Retchin, Yarden Golan , et al. · 2022

Significance Human breast milk is the nutritional food source evolved specifically to meet the needs of infants, but much remains to be learned about its composition and changes over the course of lactation. Our description of the cellular…

Cellular and transcriptional diversity over the course of human lactation Open

Sarah K. Nyquist, Patricia Gao, Tessa K. J. Haining, Michael R. Retchin, Yarden Golan Maor , et al. · 2021

Human breast milk is a dynamic fluid that contains millions of cells, but their identities and phenotypic properties are poorly understood. We used single-cell RNA-seq (scRNA-seq) to characterize the transcriptomes of cells from human brea…

Characterizing the modern light environment and its influence on circadian rhythms Open

Dennis Khodasevich, Susan Tsui, Darwin Keung, Debra J. Skene, Victoria L. Revell , et al. · 2021

Humans have largely supplanted natural light cycles with a variety of electric light sources and schedules misaligned with day-night cycles. Circadian disruption has been linked to a number of disease processes, but the extent of circadian…

Social-distancing fatigue: Evidence from real-time crowd-sourced traffic data Open

Jenni A. Shearston, Micaela E. Martinez, Yanelli Nunez, Markus Hilpert · 2021

Using crowd-sourced traffic congestion data, we described changes in mobility in Manhattan, NYC, during the COVID-19 pandemic. These data can be used to inform human mobility changes during the current pandemic, in planning for responses t…

Exploring the Seasonal Drivers of Varicella Zoster Virus Transmission and Reactivation Open

Kevin Bakker, Marisa C. Eisenberg, Robert J. Woods, Micaela E. Martinez · 2021

Varicella zoster virus (VZV) is a herpesvirus that causes chickenpox and shingles. The biological mechanisms underpinning the multidecadal latency of VZV in the body and subsequent viral reactivation—which occurs in approximately 30% of in…

Social-distancing Fatigue: Evidence from Real-time Crowd-sourced Traffic Data Open

Jenni A. Shearston, Micaela E. Martinez, Yanelli Nunez, Markus Hilpert · 2021

Introduction To mitigate the COVID-19 pandemic and prevent overwhelming the healthcare system, social-distancing policies such as school closure, stay-at-home orders, and indoor dining closure have been utilized worldwide. These policies f…

Drivers of Infectious Disease Seasonality: Potential Implications for COVID-19 Open

Noga Kronfeld‐Schor, Tyler J. Stevenson, Sema Nickbakhsh, Eva Schernhammer, Xaquín Castro Dopico , et al. · 2021

Not 1 year has passed since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19). Since its emergence, great uncertainty has surrounded the potential for …

Socioeconomic Disparities in Subway Use and COVID-19 Outcomes in New York City Open

Karla Therese L. Sy, Micaela E. Martinez, Benjamin Rader, Laura F. White · 2020

Using data from New York City from January 2020 to April 2020, we found an estimated 28-day lag between the onset of reduced subway use and the end of the exponential growth period of severe acute respiratory syndrome coronavirus 2 within …

Unmasking Seasonal Cycles in Human Fertility: How holiday sex and fertility cycles shape birth seasonality Open

Laura Symul, Pei Yang Hsieh, Alison K. Shea, Cláudia Roberta de Castro Moreno, Debra J. Skene , et al. · 2020

The mechanisms of human birth seasonality have been debated for over 150 years 1 . In particular, the question of whether sexual activity or fertility variations drive birth seasonality has remained open and challenging to test without lar…

Guidelines for Modeling and Reporting Health Effects of Climate Change Mitigation Actions Open

Jeremy Hess, Nikhil Ranadive, Christopher Boyer, Lukasz Aleksandrowicz, Susan C. Anenberg , et al. · 2020

BACKGROUND: Modeling suggests that climate change mitigation actions can have substantial human health benefits that accrue quickly and locally. Documenting the benefits can help drive more ambitious and health-protective climate change mi…

Characterizing the Modern Light Environment and its Influence on Circadian Rhythms Open

Dennis Khodasevich, Susan Tsui, Darwin Keung, Debra J. Skene, Victoria L. Revell , et al. · 2020

Humans have largely supplanted natural light cycles with a variety of artificial light sources and schedules misaligned with day-night cycles. Circadian disruption has been linked to a number of disease processes, but the extent of circadi…

Circadian Rhythms in Environmental Health Sciences Open

Jacqueline M. Leung, Micaela E. Martinez · 2020

Socioeconomic disparities in subway use and COVID-19 outcomes in New York City Open

Karla Therese L. Sy, Micaela E. Martinez, Benjamin Rader, Laura F. White · 2020

Background: The United States CDC has reported that racial and ethnic disparities in the COVID-19 pandemic may in part be due to socioeconomic disadvantages that require individuals to continue to work outside their home and a lack of paid…

Centring sexual and reproductive health and justice in the global COVID-19 response Open

Kelli Stidham Hall, Goleen Samari, Samantha Garbers, Sara E. Casey, Dázon Dixon Diallo , et al. · 2020

Rescuing Troves of Hidden Ecological Data to Tackle Emerging Mosquito-Borne Diseases Open

Samuel S. C. Rund, Imelda K. Moise, John C. Beier, Micaela E. Martinez · 2019

Despite the major impact of mosquitoes on human health, knowledge gaps exist regarding their natural population dynamics. Even the most basic information—such as spatiotemporal abundance—is mostly unavailable. In the USA, municipalities ha…

‘Tis the season for conception Open

Micaela E. Martinez, Kevin Bakker · 2018

Daylight saving time and circadian rhythms in the neuro-endocrine-immune system: impact on cardiovascular health Open

Roberto Tarquini, Annalucia Carbone, Micaela E. Martinez, Gianluigi Mazzoccoli · 2018

The calendar of epidemics: Seasonal cycles of infectious diseases Open

Micaela E. Martinez · 2018

Seasonal cyclicity is a ubiquitous feature of acute infectious diseases [1] and may be a ubiquitous feature of human infectious diseases in general, as illustrated in Tables 1–4. Each acute infectious disease has its own seasonal window of…

Benefits and Challenges in Using Seroprevalence Data to Inform Models for Measles and Rubella Elimination Open

Amy K. Winter, Micaela E. Martinez, Felicity Cutts, William J. Moss, Matt Ferrari , et al. · 2018

Accounting for the dynamical context, serosurveys could play a key role in efforts to achieve and sustain elimination.

Rescuing Troves of Data to Tackle Emerging Mosquito-Borne Diseases Open

Samuel S. C. Rund, Micaela E. Martinez · 2016

According to the World Health Organization, every year more than a billion people are infected with vector-borne diseases worldwide. There are no vaccines for most vector-borne diseases. Vector control, therefore, is often the only way to …

Preventing Zika Virus Infection during Pregnancy Using a Seasonal Window of Opportunity for Conception Open