Michael A. Harding
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View article: Circulating Extracellular Vesicles in the Pathogenesis of Heart Failure in Patients With Chronic Kidney Disease
Circulating Extracellular Vesicles in the Pathogenesis of Heart Failure in Patients With Chronic Kidney Disease Open
BACKGROUND: Cardiovascular disease causes >50% of deaths in patients with advanced chronic kidney disease (CKD). Clinical studies suggest that kidney-derived factors contribute to cardiovascular disease development in CKD, independently of…
View article: Uromodulin and the study of urinary extracellular vesicles
Uromodulin and the study of urinary extracellular vesicles Open
Urinary extracellular vesicles (uEVs) are a promising substrate for discovering new biomarkers. In order to investigate the origin of uEVs and the cargo they carry, some types of downstream analysis of uEVs may require concentration and en…
View article: Effect of the DASH diet on the sodium-chloride cotransporter and aquaporin-2 in urinary extracellular vesicles
Effect of the DASH diet on the sodium-chloride cotransporter and aquaporin-2 in urinary extracellular vesicles Open
Numerous studies link DASH diet to lower blood pressure, but its mechanism is unclear. Urinary extracellular vesicles (uEVs) offer noninvasive insights, potentially replacing tissue sampling. Transitioning to DASH diet alters kidney transp…
View article: Supplementary Figure Legends 1-5 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure Legends 1-5 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 90K
View article: Data from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Data from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
Hypoxia drives malignant progression in part by promoting accumulation of the oncogenic transcription factor hypoxia inducible factor–1α (HIF-1α) in tumor cells. Tumor aggressiveness also relates to elevation of the cancer stem cell–associ…
View article: Supplementary Table 1 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Table 1 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 68K, Quantitation of visible lung for metastases after tail vein inoculation of UMUC-3 cell lines
View article: Supplementary Figure 4 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure 4 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 88K, Western blot and ChIP for HIF-1beta in human bladder cancer cells
View article: Supplementary Figure 1 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure 1 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 25K, Detail of the gene signature of Ral-dependent transcription and molecular concepts
View article: Supplementary Figure 5 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure 5 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 890K, Effects of CD24 and HIF1a depletion on in vitro and in vivo growth and metastasis of bladder and prostate cancer cells
View article: Supplementary Figure 2 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure 2 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 158K, Evaluation of CD24 and HIF1a expression in response to hypoxia and Deferoxamine in human bladder and prostate cancer cells
View article: Supplementary Figure 1 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure 1 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 25K, Detail of the gene signature of Ral-dependent transcription and molecular concepts
View article: Supplementary Figure 4 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure 4 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 88K, Western blot and ChIP for HIF-1beta in human bladder cancer cells
View article: Supplementary Figure 5 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure 5 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 890K, Effects of CD24 and HIF1a depletion on in vitro and in vivo growth and metastasis of bladder and prostate cancer cells
View article: Supplementary Figure Legends 1-5 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure Legends 1-5 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 90K
View article: Supplementary Figure 3 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure 3 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 45K, The CD24 promoter cloned from human prostate and bladder cells
View article: Supplementary Table 1 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Table 1 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 68K, Quantitation of visible lung for metastases after tail vein inoculation of UMUC-3 cell lines
View article: Supplementary Figure 3 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure 3 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 45K, The CD24 promoter cloned from human prostate and bladder cells
View article: Data from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Data from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
Hypoxia drives malignant progression in part by promoting accumulation of the oncogenic transcription factor hypoxia inducible factor–1α (HIF-1α) in tumor cells. Tumor aggressiveness also relates to elevation of the cancer stem cell–associ…
View article: Supplementary Figure 2 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Supplementary Figure 2 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis Open
PDF file - 158K, Evaluation of CD24 and HIF1a expression in response to hypoxia and Deferoxamine in human bladder and prostate cancer cells