Michael Baram
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View article: The Discover In-Hospital Cardiac Arrest (Discover IHCA) Study: An Investigation of Hospital Practices After In-Hospital Cardiac Arrest
The Discover In-Hospital Cardiac Arrest (Discover IHCA) Study: An Investigation of Hospital Practices After In-Hospital Cardiac Arrest Open
IMPORTANCE: In-hospital cardiac arrest (IHCA) is a significant public health burden. Rates of return of spontaneous circulation (ROSC) have been improving, but the best way to care for patients after the initial resuscitation remains poorl…
View article: Importance of Reconnection With ICU Survivors to ICU Recovery Program Clinicians
Importance of Reconnection With ICU Survivors to ICU Recovery Program Clinicians Open
Presently, ICU recovery care has appropriately focused on ICU survivor and caregiver outcomes. The provision of ICU recovery services through specialized post-ICU programs are one approach clinicians and researchers have focused their effo…
View article: Design and rationale of the CHILL phase II trial of hypothermia and neuromuscular blockade for acute respiratory distress syndrome
Design and rationale of the CHILL phase II trial of hypothermia and neuromuscular blockade for acute respiratory distress syndrome Open
The Cooling to Help Injured Lungs (CHILL) trial is an open label, two group, parallel design multicenter, randomized phase IIB clinical trial assessing the efficacy and safety of targeted temperature management with combined external cooli…
View article: Systemic Inflammatory Response Syndrome After Extracorporeal Membrane Oxygenation Decannulation in COVID-19 Patients
Systemic Inflammatory Response Syndrome After Extracorporeal Membrane Oxygenation Decannulation in COVID-19 Patients Open
Post-ECMO SIRS is common. The incidence of SIRS following decannulation was similar when historically compared to non-COVID patients who survived ECMO in a previously reported cohort from our institution. Immune-modulation exposure within …
View article: Association of Renin Angiotensin Aldosterone System Inhibitors and Outcomes of Hospitalized Patients With COVID-19
Association of Renin Angiotensin Aldosterone System Inhibitors and Outcomes of Hospitalized Patients With COVID-19 Open
OBJECTIVES: To determine the association of prior use of renin-angiotensin-aldosterone system inhibitors (RAASIs) with mortality and outcomes in hospitalized patients with COVID-19. DESIGN: Retrospective observational study. SETTING: Multi…
View article: Standardization and Risk Regulation for High-Hazard Industries
Standardization and Risk Regulation for High-Hazard Industries Open
Hazardous industrial activities have historically been regulated from a safety and/or risk management viewpoint based on regulations enacted by governmental authorities. This chapter describes and explains the decline in the role played by…
View article: A multidisciplinary approach to prolonged extracorporeal membrane oxygenation for acute respiratory distress syndrome due to coronavirus 2019—case report
A multidisciplinary approach to prolonged extracorporeal membrane oxygenation for acute respiratory distress syndrome due to coronavirus 2019—case report Open
Patients with novel coronavirus 2019 (COVID-19) may develop acute respiratory distress syndrome (ARDS) and require extracorporeal membrane oxygenation (ECMO) support. Currently there is no specific treatment for COVID-19 available; thus, f…
View article: Outcomes of extracorporeal membrane oxygenation in influenza versus COVID‐19 during the first wave of COVID‐19
Outcomes of extracorporeal membrane oxygenation in influenza versus COVID‐19 during the first wave of COVID‐19 Open
COVID-19 patients who were treated in our institution with VV-ECMO had statistically lower ECMO survival rates than influenza patients. It is possible that COVID-19 immunomodulation therapies may increase the risk of other superimposed inf…
View article: COVID-19 treatment combinations and associations with mortality in a large multi-site healthcare system
COVID-19 treatment combinations and associations with mortality in a large multi-site healthcare system Open
Introduction During the early months of the COVID-19 pandemic, mortality associated with the disease declined in the United States. The standard of care for pharmacological interventions evolved during this period as new and repurposed tre…
View article: Outcomes of Extracorporeal Membrane Oxygenation in Influenza vs. COVID-19 During the First Wave of COVID-19
Outcomes of Extracorporeal Membrane Oxygenation in Influenza vs. COVID-19 During the First Wave of COVID-19 Open
Purpose: Extracorporeal membrane oxygenation (ECMO) is a refractory treatment for acute respiratory distress syndrome (ARDS) due to influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, also referred to as COVID-19). W…
View article: Outcomes of extracorporeal membrane oxygenation in acute respiratory distress syndrome due to COVID‐19: The lessons learned from the first wave of COVID‐19
Outcomes of extracorporeal membrane oxygenation in acute respiratory distress syndrome due to COVID‐19: The lessons learned from the first wave of COVID‐19 Open
Based on our experience, ECMO can improve refractory ARDS due to COVID-19 in select patients. Proper control of bacterial infections during COVID-19 immunomodulation therapy may be critical to improving survival.
View article: Outcomes of Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome due to COVID-19, lessons learned from the first wave of COVID 19
Outcomes of Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome due to COVID-19, lessons learned from the first wave of COVID 19 Open
Introduction: Extracorporeal membrane oxygenation (ECMO) has been used as a refractory treatment for acute respiratory distress syndrome (ARDS) due to COVID-19, but there has been little evidence of its efficacy. We conducted this study to…
View article: The Social Control of Science and Technology
The Social Control of Science and Technology Open
Science and technology increasingly work changes in the complex matrix of society. These changes pervade our ecological systems and our physical and psychic health. Less perceptibly, they pervade our culture, our values, and our value base…
View article: Development and Validation of a Web-Based Severe COVID-19 Risk Prediction Model
Development and Validation of a Web-Based Severe COVID-19 Risk Prediction Model Open
Background Coronavirus disease 2019 (COVID-19) carries high morbidity and mortality globally. Identification of patients at risk for clinical deterioration upon presentation would aid in triaging, prognostication, and allocation of resourc…
View article: Impact of Vasopressor Initiation and Discontinuation Sequence on Mortality in Septic Shock: A Retrospective Review
Impact of Vasopressor Initiation and Discontinuation Sequence on Mortality in Septic Shock: A Retrospective Review Open
Background: Little data exists guiding clinicians on how or when to initiate and discontinue the second vasoactive agent in the setting of septic shock refractory to norepinephrine monotherapy. Methods: This retrospective cohort study eval…
View article: Role of Serum Cytokine Levels in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation Support
Role of Serum Cytokine Levels in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation Support Open
Background: Even with the use of extracorporeal membrane oxygenation (ECMO) in acute respiratory distress syndrome (ARDS), mortality remains high. Also, prognostication of patients with ARDS and ECMO is difficult. Cytokines are thought to …
View article: Resilience and Essential Public Infrastructure
Resilience and Essential Public Infrastructure Open
This chapter begins with a commentary on resilience as the meta-concept for organizational preparedness for disruptive events, and the factors that influence the implementation of a resilience agenda. This is followed by an analysis of res…
View article: AMJ volume 44 issue 1 Cover and Front matter
AMJ volume 44 issue 1 Cover and Front matter Open
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