Christopher M. Wright
YOU?
Author Swipe
View article: Inferring magnetic field morphology and dust scattering geometry from mid-IR polarimetry: the Extended Aitken Method
Inferring magnetic field morphology and dust scattering geometry from mid-IR polarimetry: the Extended Aitken Method Open
The Aitken method is a useful approach for decomposing mid-IR polarimetry of silicates in astronomical sources into emissive and absorptive components. Here, we extend this method to include the effects of polarization caused by scattering…
View article: Bridging radiotherapy before chimeric antigen receptor T cells for B-cell lymphomas: an ILROG multicenter study
Bridging radiotherapy before chimeric antigen receptor T cells for B-cell lymphomas: an ILROG multicenter study Open
Despite the increasing utilization of bridging radiotherapy (Br-RT), its impact on chimeric antigen receptor T-cell therapy (CAR-T) efficacy and toxicity remains poorly characterized. We retrospectively reviewed patients with relapsed/refr…
View article: Muscle in the caterpillar<i>Manduca sexta</i>responds to an immune challenge, but at a cost, suggesting a physiological trade-off
Muscle in the caterpillar<i>Manduca sexta</i>responds to an immune challenge, but at a cost, suggesting a physiological trade-off Open
Although skeletal muscle is a specialized tissue that provides the motor for movement, it also participates in other functions, including the immune response. However, little is known about the effects of this multitasking on muscle. We sh…
View article: Data from Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer
Data from Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer Open
Elevated oxidative stress is an aberration seen in many solid tumors, and exploiting this biochemical difference has the potential to enhance the efficacy of anticancer agents. Homeostasis of reactive oxygen species (ROS) is important for …
View article: Supplemental Methods from Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer
Supplemental Methods from Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer Open
Description of additional methods and procedures used in the study.
View article: Supplemental Figures S1-S7 from Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer
Supplemental Figures S1-S7 from Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer Open
Fbln5 and α5β1 integrin expression pattern in mouse and human (S1); Characterization of KIC and KPC mice (S2); Examination of ROS levels in normal pancreas and NAC-treated KIC and RGE KIC tumors (S3); Reduced microvessel density (MVD) in R…
View article: Supplemental Methods from Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer
Supplemental Methods from Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer Open
Description of additional methods and procedures used in the study.
View article: GTC/CanariCam Mid-IR Polarimetry of Magnetic Fields in Star-Forming Region W51 IRS2
GTC/CanariCam Mid-IR Polarimetry of Magnetic Fields in Star-Forming Region W51 IRS2 Open
We present 0.4 arcsec-resolution imaging polarimetry at 8.7, 10.3, and 12.5 microns, obtained with CanariCam at the Gran Telescopio Canarias, of the central region of W51 IRS2. The polarization, as high as 14 percent, arises from silicate …
View article: Exploration of radiation-induced lung injury, from mechanism to treatment: a narrative review
Exploration of radiation-induced lung injury, from mechanism to treatment: a narrative review Open
The occurrence of RILI after radiotherapy will greatly affect the prognosis and quality of life of patients. In clinical practice, early intervention, active treatment, and more effective therapeutic drugs should be found.
View article: Dosimetric Results for Adjuvant Proton Radiation Therapy of HPV-Associated Oropharynx Cancer
Dosimetric Results for Adjuvant Proton Radiation Therapy of HPV-Associated Oropharynx Cancer Open
Our study suggests that meaningful normal tissue sparing in the postoperative setting is achievable with PRT, without impacting disease outcomes.
View article: Low-Dose Radiotherapy Versus Moderate-Dose Radiotherapy for the Treatment of Indolent Orbital Adnexal Lymphomas
Low-Dose Radiotherapy Versus Moderate-Dose Radiotherapy for the Treatment of Indolent Orbital Adnexal Lymphomas Open
Purpose Radiation therapy (RT) with doses ranging from 24 Gray (Gy) to 40 Gy is a proven treatment modality for indolent orbital adnexal lymphoma (IOAL), but recently the use of low dose RT (LDRT, defined as 2 Gy x 2 fractions) has become …
View article: Financial relationships between industry and principal investigators of US cooperative group randomized cancer clinical trials
Financial relationships between industry and principal investigators of US cooperative group randomized cancer clinical trials Open
Financial conflicts of interest (FCOIs) could bias the potentially practice‐changing oncologic randomized clinical trials (RCTs) of tomorrow. This investigation characterized the FCOIs of the principal investigators (PIs) of all currently …
View article: Radiation Therapy for Chemotherapy Refractory Gingival Myeloid Sarcoma
Radiation Therapy for Chemotherapy Refractory Gingival Myeloid Sarcoma Open
Gingival myeloid sarcoma (MS) refractory to induction chemotherapy is a rare clinical entity and can be treated with palliative radiation therapy (RT). However, there are few previously published reports of RT approaches for the treatment …
View article: Quantitation and predictors of short-term mortality following extrapleural pneumonectomy, pleurectomy/decortication, and nonoperative management for malignant pleural mesothelioma
Quantitation and predictors of short-term mortality following extrapleural pneumonectomy, pleurectomy/decortication, and nonoperative management for malignant pleural mesothelioma Open
Quantitative estimates of age-associated 30- and 90-day mortality of EPP and P/D should be considered when potentially operable patients are counseled regarding the risks and benefits of resection.
View article: Initial clinical experience treating patients with palliative radiotherapy for malignant pleural mesothelioma on the HalcyonTM linear accelerator
Initial clinical experience treating patients with palliative radiotherapy for malignant pleural mesothelioma on the HalcyonTM linear accelerator Open
In this initial clinical experience treating patients with palliative RT for MPM on HalcyonTM, treatment provided symptom palliation and local control across multiple palliative scenarios, with minimal toxicity, acceptable dosimetry, and s…
View article: Is Host Metabolism the Missing Link to Improving Cancer Outcomes?
Is Host Metabolism the Missing Link to Improving Cancer Outcomes? Open
For the past 100 years, oncologists have relentlessly pursued the destruction of tumor cells by surgical, chemotherapeutic or radiation oncological means. Consistent with this focus, treatment plans are typically based on key characteristi…