Michael J. Cronin
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View article: 7 Evaluating the cost-effectiveness of an accelerated outpatient coronary CT angiography pathway in the emergency department: insights from an Irish tertiary centre
7 Evaluating the cost-effectiveness of an accelerated outpatient coronary CT angiography pathway in the emergency department: insights from an Irish tertiary centre Open
View article: Seeking out the primary tumour: multi-modality imaging of metastatic cardiac angiosarcoma
Seeking out the primary tumour: multi-modality imaging of metastatic cardiac angiosarcoma Open
View article: Building trust and warmth: Co-designing energy solutions with travellers and displaced communities in Ireland
Building trust and warmth: Co-designing energy solutions with travellers and displaced communities in Ireland Open
View article: Management of Coronary Artery Disease in the Context of Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis of Percutaneous Coronary Intervention Timing and an Algorithmic Approach to Management
Management of Coronary Artery Disease in the Context of Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis of Percutaneous Coronary Intervention Timing and an Algorithmic Approach to Management Open
Background: Transcatheter aortic valve implantation (TAVI) is widely performed for severe aortic stenosis (AS), often accompanied by coronary artery disease (CAD). The optimal management of CAD in TAVI patients remains uncertain. This stud…
View article: The pseudoknot structure of a viral RNA reveals a conserved mechanism for programmed exoribonuclease resistance
The pseudoknot structure of a viral RNA reveals a conserved mechanism for programmed exoribonuclease resistance Open
Exoribonuclease-resistant RNAs (xrRNAs) are viral RNA structures that block degradation by cellular 5′-3′ exoribonucleases to produce subgenomic viral RNAs during infection. Initially discovered in flaviviruses, xrRNAs have since been iden…
View article: Proposed framework regarding management of patients with breast cancer and anti-cancer treatment-related elevation in cardiac troponin
Proposed framework regarding management of patients with breast cancer and anti-cancer treatment-related elevation in cardiac troponin Open
View article: Understanding cardiac events in breast cancer (UCARE): pilot cardio-oncology assessment and surveillance pathway for breast cancer patients
Understanding cardiac events in breast cancer (UCARE): pilot cardio-oncology assessment and surveillance pathway for breast cancer patients Open
Purpose In Ireland, over 3000 patients are diagnosed with breast cancer annually, and 1 in 9 Irish women will be diagnosed with breast cancer in their lifetime. There is evidence that female breast cancer survivors are more likely to die o…
View article: The early after discharge cardiac CT for low-risk chest pain study: the ED-CT study
The early after discharge cardiac CT for low-risk chest pain study: the ED-CT study Open
Objectives An accelerated diagnostic pathway is created to aid the management of low-risk patients presenting to the emergency room with chest pain. Records are taken of patient outcomes and factors influencing physician decision-making be…
View article: Risk Prediction, Diagnosis and Management of a Breast Cancer Patient with Treatment-Related Cardiovascular Toxicity: An Essential Overview
Risk Prediction, Diagnosis and Management of a Breast Cancer Patient with Treatment-Related Cardiovascular Toxicity: An Essential Overview Open
Breast cancer is amongst the most common invasive cancers in adults. There are established relationships between anti-cancer treatments for breast cancer and cardiovascular side effects. In recent years, novel anti-cancer treatments have b…
View article: Understanding Cardiac Events in Breast Cancer (UCARE) - Pilot Cardio-Oncology Assessment and Surveillance Pathway for Breast Cancer Patients
Understanding Cardiac Events in Breast Cancer (UCARE) - Pilot Cardio-Oncology Assessment and Surveillance Pathway for Breast Cancer Patients Open
In Ireland, over 3,000 patients are diagnosed with breast cancer annually, and 1 in 9 Irish women will be diagnosed with breast cancer in their lifetime. There is evidence that female breast cancer survivors are more likely to die of cardi…
View article: Multimodal Imaging of Cancer Therapy-Related Cardiac Dysfunction in Breast Cancer—A State-of-the-Art Review
Multimodal Imaging of Cancer Therapy-Related Cardiac Dysfunction in Breast Cancer—A State-of-the-Art Review Open
Background: This review focuses on multimodality imaging of cardiotoxicity in cancer patients, with the aim of evaluating the effectiveness of different techniques in detecting and monitoring cardiac changes associated with cancer therapy.…
View article: Heart Failure Association-International Cardio-Oncology Society Risk Score Validation in HER2-Positive Breast Cancer
Heart Failure Association-International Cardio-Oncology Society Risk Score Validation in HER2-Positive Breast Cancer Open
Background: This paper looks to validate the risk score from the Heart Failure Association of the European Society of Cardiology and the International Cardio-Oncology Society (HFA-ICOS) for predicting potential cardiotoxicity from anticanc…
View article: Supervision of Surgical Trainees During Operative Procedures: Implementation of a Formal Preoperative Surgical Checklist
Supervision of Surgical Trainees During Operative Procedures: Implementation of a Formal Preoperative Surgical Checklist Open
Background Trainers in surgery have an educational obligation to train trainees in performing operative procedures. Objective We hypothesized that poor concordance manifests as discrepancies between the trainee and the trainer, with an ass…
View article: Identifying dynamic changes following traumatic brain injury using high resolution magnetic resonance images derived texture analysis
Identifying dynamic changes following traumatic brain injury using high resolution magnetic resonance images derived texture analysis Open
View article: 25 CT coronary angiography and COVID-19: inpatient use in acute chest pain service
25 CT coronary angiography and COVID-19: inpatient use in acute chest pain service Open
Introduction CT coronary angiography (CTCA) is a well-validated clinical tool in the evaluation of chest pain. In January 2020 a care pathway was agreed between the cardiology, radiology and emergency departments in our facility to impleme…
View article: Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated
Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated Open
Exercise mobilizes angiogenic cells, which stimulate vascular repair. However, limited research suggests exercise-induced increase of endothelial progenitor cell (EPCs) is completely lacking in type 1 diabetes (T1D). Clarification, along w…
View article: CT coronary angiography and COVID-19: inpatient use in acute chest pain service
CT coronary angiography and COVID-19: inpatient use in acute chest pain service Open
Objectives CT coronary angiography (CTCA) is a well-validated clinical tool in the evaluation of chest pain. In our institution, CTCA availability was increased in January 2020, and subsequently, expanded further to replace all exercise te…
View article: Angiotensin-converting enzyme inhibitor-induced oropharyngeal edema with subsequent stress-cardiomyopathy
Angiotensin-converting enzyme inhibitor-induced oropharyngeal edema with subsequent stress-cardiomyopathy Open
Intramuscular adrenaline is a standard treatment approach for the symptomatic patient presenting with distress and oropharyngeal edema, requiring subsequent doses if oedema persists. This case demonstrates a delayed side-effect of stress-i…
View article: Quantitation of Human Immunodeficiency Virus Type 1 RNA in Plasma by Using Blood Dried on Filter Paper
Quantitation of Human Immunodeficiency Virus Type 1 RNA in Plasma by Using Blood Dried on Filter Paper Open
We compared whole blood dried on filter paper to the standard assay with frozen cell-free plasma for use in the quantitation of the human immunodeficiency virus RNA load in blood. RNA values from filter paper, corrected for the hematocrit,…
View article: Insulin hypersensitivity in type 1 diabetes: investigation and treatment with immunodepletion
Insulin hypersensitivity in type 1 diabetes: investigation and treatment with immunodepletion Open
A 12‐year‐old girl presented with type 1 diabetes which was well controlled for the first two years. Glycaemic control then markedly deteriorated with a very large increase in insulin requirement and the appearance of inflammatory nodules …
View article: 26 A retrospective audit of in-hospital 30-day mortality from acute myocardial infarction in connolly hospital blanchardstown
26 A retrospective audit of in-hospital 30-day mortality from acute myocardial infarction in connolly hospital blanchardstown Open
Background In March 2015 The Department of Health published the first annual report of the “National Healthcare Quality Reporting System.” This was designed to report the quality of healthcare provided across all sectors of our system. Th…