Michael Cruise
YOU?
Author Swipe
View article: Double Trouble: Synchronous Small Cell Carcinoma and Adenocarcinoma of the Pancreas – Case Report
Double Trouble: Synchronous Small Cell Carcinoma and Adenocarcinoma of the Pancreas – Case Report Open
Introduction: Simultaneous presentation of primary tumors involving one isolated organ is few and far between. Pancreatic small cell carcinoma is unique, and it is rare to have both adenocarcinoma and small cell carcinoma present in unison…
View article: Endoscopic screening for identification of signet ring cell gastric cancer foci in carriers of germline pathogenic variants in CDH1
Endoscopic screening for identification of signet ring cell gastric cancer foci in carriers of germline pathogenic variants in CDH1 Open
To determine the preoperative detection of signet ring cancer cells (SRC) on upper endoscopy (EGD) in patients with CDH1 pathogenic variant (PV) undergoing gastrectomy. To evaluate the development of advanced diffuse gastric cancer (DGC) i…
View article: Endoscopic Screening for Identification of Signet Ring Cell Gastric Cancer Foci in Carriers of Germline Pathogenic Variants in CDH1
Endoscopic Screening for Identification of Signet Ring Cell Gastric Cancer Foci in Carriers of Germline Pathogenic Variants in CDH1 Open
Objective: To determine the preoperative detection of signet ring cancer cells (SRC) on upper endoscopy (EGD) in patients with CDH1 pathogenic variant (PV) undergoing gastrectomy. To evaluate the development of advanced diffuse gastric can…
View article: Supplementary Figure S3 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Figure S3 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Figure S3. Characterization of immune infiltration in MSS CRC outlier.
View article: Supplementary Figure S1 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Figure S1 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Figure S1. Laser capture microdissection of FFPE tissue sections.
View article: Data from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Data from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
We examined the immune microenvironment of primary colorectal cancer using immunohistochemistry, laser capture microdissection/qRT-PCR, flow cytometry, and functional analysis of tumor-infiltrating lymphocytes. A subset of colorectal cance…
View article: Supplementary Figure S4 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Figure S4 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Figure S4. PD-L1 induction on human CRC cell lines.
View article: Supplementary Table S2 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Table S2 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Table S2. Exome sequencing of MSS tumor outlier.
View article: Supplementary Figure S4 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Figure S4 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Figure S4. PD-L1 induction on human CRC cell lines.
View article: Data from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Data from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
We examined the immune microenvironment of primary colorectal cancer using immunohistochemistry, laser capture microdissection/qRT-PCR, flow cytometry, and functional analysis of tumor-infiltrating lymphocytes. A subset of colorectal cance…
View article: Supplementary Table S2 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Table S2 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Table S2. Exome sequencing of MSS tumor outlier.
View article: Supplementary Table S1 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Table S1 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Table S1. Patient Demographics.
View article: Supplementary Figure S2 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Figure S2 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Figure S2. Absolute numbers of CD3 cells per gram of tumor and normal colon tissue collected from MSS and MSI human CRC patients.
View article: Supplementary Figure S2 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Figure S2 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Figure S2. Absolute numbers of CD3 cells per gram of tumor and normal colon tissue collected from MSS and MSI human CRC patients.
View article: Supplementary Table S3 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Table S3 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Table S3. Primers/probes used for Taqman PCR array.
View article: Supplementary Figure S3 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Figure S3 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Figure S3. Characterization of immune infiltration in MSS CRC outlier.
View article: Supplementary Table S1 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Table S1 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Table S1. Patient Demographics.
View article: Supplementary Table S3 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Table S3 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Table S3. Primers/probes used for Taqman PCR array.
View article: Supplementary Figure S1 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Supplementary Figure S1 from The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints Open
Supplementary Figure S1. Laser capture microdissection of FFPE tissue sections.
View article: Identifying factors associated with detection of sessile gastric polyps in patients with familial adenomatous polyposis
Identifying factors associated with detection of sessile gastric polyps in patients with familial adenomatous polyposis Open
Background and study aims Gastric cancer (GC) is increasingly reported and a leading cause of death in patients with familial adenomatous polyposis (FAP). Identifying features in patients with FAP who harbor sessile gastric polyps, likely …
View article: A Model for Design and Implementation of a Laboratory Information-Management System Specific for Molecular Pathology Laboratory Operations
A Model for Design and Implementation of a Laboratory Information-Management System Specific for Molecular Pathology Laboratory Operations Open
The Molecular Pathology Section, Cleveland Clinic (Cleveland, OH), has undergone enhancement of its testing portfolio and processes. An Excel 2013- and paper-based data-management system was replaced with a commercially available laborator…
View article: Finding the needle in a haystack: approach to detection of high-risk gastric lesions in familial adenomatous polyposis
Finding the needle in a haystack: approach to detection of high-risk gastric lesions in familial adenomatous polyposis Open
View article: Response
Response Open
View article: Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity
Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity Open
The pathogenesis of ulcerative colitis (UC), a major type of inflammatory bowel disease, remains unknown. No model exists that adequately recapitulates the complexity of clinical UC. Here, we take advantage of induced pluripotent stem cell…
View article: Endoscopic Recognition and Management Strategies for Malignant Colorectal Polyps: Recommendations of the US Multi-Society Task Force on Colorectal Cancer
Endoscopic Recognition and Management Strategies for Malignant Colorectal Polyps: Recommendations of the US Multi-Society Task Force on Colorectal Cancer Open
View article: Loss of β-Cytoplasmic Actin in the Intestinal Epithelium Increases Gut Barrier Permeability in vivo and Exaggerates the Severity of Experimental Colitis
Loss of β-Cytoplasmic Actin in the Intestinal Epithelium Increases Gut Barrier Permeability in vivo and Exaggerates the Severity of Experimental Colitis Open
Intestinal epithelial barrier is critical for the maintenance of normal gut homeostasis and disruption of this barrier may trigger or exaggerate mucosal inflammation. The actin cytoskeleton is a key regulator of barrier structure and funct…
View article: Operationalizing COVID-19 testing: Who, what, when, where, why, and how
Operationalizing COVID-19 testing: Who, what, when, where, why, and how Open
The authors review the rationale behind and approaches to testing for COVID-19, the quality of currently available tests, the role of data analytics in strategizing testing, and using the electronic medical record and other programs design…
View article: Selective deletion of MyD88 signaling in α-SMA positive cells ameliorates experimental intestinal fibrosis via post-transcriptional regulation
Selective deletion of MyD88 signaling in α-SMA positive cells ameliorates experimental intestinal fibrosis via post-transcriptional regulation Open
View article: Disseminated Metacestode <i>Versteria</i> Species Infection in Woman, Pennsylvania, USA1
Disseminated Metacestode <i>Versteria</i> Species Infection in Woman, Pennsylvania, USA1 Open
A patient in Pennsylvania, USA, with common variable immunodeficiency sought care for fever, cough, and abdominal pain. Imaging revealed lesions involving multiple organs. Liver resection demonstrated necrotizing granulomas, recognizable t…
View article: 737 – The Prevalence and Significance of Duodenal Bulb Polyposis After Duodenectomy in Patients with Familial Adenomatous Polyposis
737 – The Prevalence and Significance of Duodenal Bulb Polyposis After Duodenectomy in Patients with Familial Adenomatous Polyposis Open