Michael D. Morrison
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View article: Microbiome dynamics in the congregate environment of U.S. Army Infantry training
Microbiome dynamics in the congregate environment of U.S. Army Infantry training Open
Within military training and operational environments, individuals from diverse backgrounds share common spaces, follow structured routines and diets, and engage in physically demanding tasks. While there has been interest in leveraging mi…
View article: Efforts to enhance reproducibility in a human performance research project
Efforts to enhance reproducibility in a human performance research project Open
Background: Ensuring the validity of results from funded programs is a critical concern for agencies that sponsor biological research. In recent years, the open science movement has sought to promote reproducibility by encouraging sharing …
View article: Evaluation of co-circulating pathogens and microbiome from COVID-19 infections
Evaluation of co-circulating pathogens and microbiome from COVID-19 infections Open
Co-infections or secondary infections with SARS-CoV-2 have the potential to affect disease severity and morbidity. Additionally, the potential influence of the nasal microbiome on COVID-19 illness is not well understood. In this study, we …
View article: Metagenomic features of bioburden serve as outcome indicators in combat extremity wounds
Metagenomic features of bioburden serve as outcome indicators in combat extremity wounds Open
Battlefield injury management requires specialized care, and wound infection is a frequent complication. Challenges related to characterizing relevant pathogens further complicates treatment. Applying metagenomics to wounds offers a compre…
View article: Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station
Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station Open
Background The International Space Station (ISS) is a unique and complex built environment with the ISS surface microbiome originating from crew and cargo or from life support recirculation in an almost entirely closed system. The Microbia…
View article: Genetic mapping of Uba3O.2.2, a pupal lethal mutation in Drosophila melanogaster
Genetic mapping of Uba3O.2.2, a pupal lethal mutation in Drosophila melanogaster Open
Induced ethyl methanesulfonate (EMS) mutations were genetically screened utilizing the FLP/FRT recombinase system to study cell overgrowth phenotypes in mosaic eyes of Drosophila melanogaster. EMS is a mutagen typically resulting in single…
View article: Additional file 4 of Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station
Additional file 4 of Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station Open
Additional file 4: Dataset S2. The percent completion, contamination, GC content, taxonomy, N50 (a measure of assembly quality) and genome size.
View article: Additional file 6 of Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station
Additional file 6 of Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station Open
Additional file 6: Dataset S4. Read counts of detected species in each sample and control. Only those species with over 100 read counts across all samples/controls were included. “F” referes to flight group, xS referes to location. “P” ref…
View article: Additional file 5 of Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station
Additional file 5 of Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station Open
Additional file 5: Dataset S3. Complete list of each COG ID.
View article: Additional file 3 of Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station
Additional file 3 of Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station Open
Additional file 3: Dataset S1. Read counts by Kingdom.
View article: COVID-19 Testing R&D (Final Report)
COVID-19 Testing R&D (Final Report) Open
Eleven Labs within the US Department of Energy (DOE), National Virtual Biotechnology Laboratory (NVBL), came together as a team to address significant R&D gaps in COVID-19 testing. Beginning in March 2020, the NVBL COVID Testing Team devel…
View article: Investigation of Spaceflight Induced Changes to Astronaut Microbiomes
Investigation of Spaceflight Induced Changes to Astronaut Microbiomes Open
The International Space Station (ISS) is a uniquely enclosed environment that has been continuously occupied for the last two decades. Throughout its operation, protecting the health of the astronauts on-board has been a high priority. The…
View article: Comparison of Bacillus subtilis transcriptome profiles from two separate missions to the International Space Station
Comparison of Bacillus subtilis transcriptome profiles from two separate missions to the International Space Station Open
The human spaceflight environment is notable for the unique factor of microgravity, which exerts numerous physiologic effects on macroscopic organisms, but how this environment may affect single-celled microbes is less clear. In an effort …
View article: Meta-analysis of data from spaceflight transcriptome experiments does not support the idea of a common bacterial “spaceflight response”
Meta-analysis of data from spaceflight transcriptome experiments does not support the idea of a common bacterial “spaceflight response” Open
Several studies have been undertaken with the goal of understanding how bacterial transcriptomes respond to the human spaceflight environment. However, these experiments have been conducted using a variety of organisms, media, culture cond…
View article: Cultivation in Space Flight Produces Minimal Alterations in the Susceptibility of Bacillus subtilis Cells to 72 Different Antibiotics and Growth-Inhibiting Compounds
Cultivation in Space Flight Produces Minimal Alterations in the Susceptibility of Bacillus subtilis Cells to 72 Different Antibiotics and Growth-Inhibiting Compounds Open
Past results have suggested that bacterial antibiotic susceptibility is altered during space flight. To test this notion, Bacillus subtilis cells were cultivated in matched hardware, medium, and environmental conditions either in space fli…