Explanipedia

Parasite genotype is a risk factor for Sarcocystis neurona-associated mortality in southern sea otters (Enhydra lutris nereis) Open

Devinn M. Sinnott, Melissa A. Miller, Elizabeth VanWormer, Francesca Batac, Katherine Greenwald , et al. · 2025

Can predictive and functional methods locate the dysplastic hip joint center? Open

Michael D. Harris, Emma C Behrman, Keith R. Lohse, Molly C. Shepherd, Bruce A. MacWilliams , et al. · 2025

Although no method is perfect, in the absence of imaging data and an anatomic HJC, this study supports the predictive Harrington (pelvis-only) HJC as the most appropriate for dysplastic hips.

Fatal Toxoplasma gondii COUG strain infections in southern sea otters (Enhydra lutris nereis): New insight on contributing factors and parasite serotyping Open

Devinn M. Sinnott, Melissa A. Miller, David Arranz-Solís, Felipe Rodriguez, Jeroen P. J. Saeij , et al. · 2025

Fatal infections with the rare COUG strain of the zoonotic parasite Toxoplasma gondii were recently detected for the first time in four southern sea otters ( Enhydra lutris nereis ) exhibiting severe protozoal steatitis. The objectives of …

EP2.8 Dynamic Coverage Following Periacetabular Osteotomy Surgery for Dysplastic Hips Open

Christina Bourantas, Emma C Behrman, Molly C. Shepherd, John C. Clohisy, Michael D. Harris · 2025

Developmental dysplasia of the hip (DDH) is an arthritis-causing disorder that reduces hip stability due to insufficient coverage of the femoral head. [1,2] One treatment focuses on reorienting the acetabulum using periacetabular osteotomy…

OP2.6 Periacetabular Osteotomy and Combined Femoral Head-Neck Junction Osteochondroplasty: A Concise Follow-up of a Previous Report at a mean of 10 years Open

Kyle P. O’Connor, Frank W. Parilla, Michael D. Harris, Jeffrey J. Nepple, Cecilia Pascual‐Garrido , et al. · 2025

Background: Hip dysplasia is a well-known cause of hip dysfunction and secondary osteoarthritis in the young adult population that is commonly treated by periacetabular osteotomy (PAO). Contemporary treatment for hip dysplasia includes PAO…

FP8.9 Identifying Risk Factors for Disease Progression in Developmental Dysplasia of the Hip Using a Contralateral Hip Model Open

Michael D. Harris, Susan Thapa, Elizabeth G. Lieberman, Wahid Abu‐Amer, Cecilia Pascual Garrido , et al. · 2025

Background: Developmental dysplasia of the hip can cause pain and premature osteoarthritis. The risk factors and timing for disease progression in adolescents and young adults has not been fully defined. This study aimed to determine the i…

EP6.10 Relationship Between Activity Levels and Patient Reported Outcomes in Individuals with Hip Dysplasia Open

Christina Bourantas, Molly C. Shepherd, Madison Wissman, John C. Clohisy, Michael D. Harris · 2025

Developmental dysplasia of the hip (DDH) reduces hip stability and increases osteoarthritis risk. [1,2] Many individuals with DDH are young and highly active but may limit activity and seek surgical intervention because of insidious pain. …

EP6.19 CT imaging findings in symptomatic FAI: A Systematic Review Open

Deniz Ince, Kyle P. O’Connor, John C. Clohisy, Jeffrey J. Nepple, Michael D. Harris · 2025

Background: Femoroacetabular impingement (FAI) is a leading cause of hip pain in young adults and a cause of osteoarthritis. Despite the prevalence of FAI, patients often experience delays in diagnosis and variable use of CT imaging in the…

EP2.44 The Impact of Periacetabular Osteotomy on the Contralateral Hip Open

Madison Wissman, Molly C. Shepherd, John C. Clohisy, Michael D. Harris · 2025

Developmental dysplasia of the hip (DDH) is characterized by a shallow acetabulum and causes joint instability and increases risk for early osteoarthritis [1]. This abnormal bone geometry increases demands on the hip abductor muscles, whic…

EP3.25 Medial Joint Forces are Elevated during Running in Dysplastic Hips Open

Molly C. Shepherd, John C. Clohisy, Michael D. Harris · 2025

Developmental dysplasia of the hip (DDH) is characterized by a shallow acetabulum that increases loading on the joint,[1,2] leading to chondrolabral damage and early osteoarthritis.[3] Many patients with symptomatic DDH are young and activ…

Altered Joint Forces Found in Symptomatic Dysplastic Hips in Women During Sport-Specific Activities Open

Molly C. Shepherd, Rannon Huo, John C. Clohisy, Jeffrey J. Nepple, Michael D. Harris · 2025

Background: Many patients with developmental dysplasia of the hip (DDH) are young and highly active but often become limited by activity-induced pain. Characterizing how the abnormal bony geometry of DDH affects hip joint loading and multi…

Environmental surveillance of soil-transmitted helminths and other enteric pathogens in settings without networked wastewater infrastructure Open

Joël Edoux Eric Siko, Kendra Joy Dahmer, Zayina Zondervenni Manoharan, Ajithkumar Muthukumar, Heather K. Amato , et al. · 2025

Soil-transmitted helminths (STH) are one of the most prevalent enteric infections world-wide. To control STH-related morbidity, the World Health Organization recommends targeted deworming and improvements in water, sanitation and hygiene. …

Environmental surveillance of soil-transmitted helminths and other enteric pathogens in settings without networked wastewater infrastructure Open

Joël Edoux Eric Siko, Kendra Joy Dahmer, Zayina Zondervenni Manoharan, Ajithkumar Muthukumar, Heather K. Amato , et al. · 2024

Soil-transmitted helminths (STH) are one of the most prevalent enteric infections world-wide. To control STH-related morbidity, the World Health Organization recommends targeted deworming and improvements in water, sanitation and hygiene. …

Soil surveillance for monitoring soil-transmitted helminths: Method development and field testing in three countries Open

Malathi Manuel, Heather K. Amato, Nils Pilotte, Benard Chieng, Sylvie Araka , et al. · 2024

Background One-fifth of the global population is infected with soil-transmitted helminths (STH). Mass drug administration (MDA) with deworming medication is widely implemented to control morbidity associated with STH infections. However, s…

Femurs in patients with hip dysplasia have fundamental shape differences compared with cam femoroacetabular impingement Open

Michael D. Harris, Brecca M.M. Gaffney, John C. Clohisy, Cecilia Pascual‐Garrido · 2024

Femoral deformities are common in developmental dysplasia of the hip (DDH), but decisions about how to treat them are not standardized. Of interest are deformities that may be akin to cam femoroacetabular impingement (FAI). We used three-d…

Can Predictive and Functional Methods Locate the Dysplastic Hip Joint Center? Open

Michael D. Harris, Emma C Behrman, Keith R. Lohse, Erin M. Mannen · 2024

Soil surveillance for monitoring soil-transmitted helminth infections: method development and field testing in three countries Open

Malathi Manuel, Heather K. Amato, Nils Pilotte, Benard Chieng, Sylvie Araka , et al. · 2023

One-fifth of the global population is infected with soil-transmitted helminths (STH). Mass drug administration (MDA) with deworming medication is widely implemented to control morbidity associated with STH infections. However, surveillance…

Arthritis Foundation/HSS Workshop on Hip Osteoarthritis, Part 2: Detecting Hips at Risk: Early Biomechanical and Structural Mechanisms Open

Maria T. Vassileva, Jason Kim, Alejandro González Della Valle, Michael D. Harris, Valentina Pedoia , et al. · 2023

Far more publications are available for osteoarthritis of the knee than of the hip. Recognizing this research gap, the Arthritis Foundation (AF), in partnership with the Hospital for Special Surgery (HSS), convened an in-person meeting of …

Are Abnormal Muscle Biomechanics and Patient-reported Outcomes Associated in Patients With Hip Dysplasia? Open

Tina Wu, Keith R. Lohse, Linda Van Dillen, Ke Song, John C. Clohisy , et al. · 2023

Background Developmental dysplasia of the hip (DDH) is a major risk factor for the early development of hip osteoarthritis. Recent studies have demonstrated how DDH alters hip muscle moment arms and elevates muscle-induced biomechanical va…

Newly detected, virulent Toxoplasma gondii COUG strain causing fatal steatitis and toxoplasmosis in southern sea otters (Enhydra lutris nereis) Open

Melissa A. Miller, Cara A. Newberry, Devinn M. Sinnott, Francesca Batac, Katherine Greenwald , et al. · 2023

From February 2020 to March 2022, four southern sea otters ( Enhydra lutris nereis ) stranded in California with severe protozoal steatitis and systemic toxoplasmosis. Three of the infected otters stranded within 26 km of each other, and a…

Derotational femoral osteotomy locations and their influence on joint reaction forces in dysplastic hips Open

Molly C. Shepherd, John C. Clohisy, Jeffrey J. Nepple, Michael D. Harris · 2023

Femoral version (FV) deformities are common in patients with developmental dysplasia of the hip (DDH) and may contribute to cartilage damage due to abnormal joint loading. Derotational femoral osteotomy (DFO) surgery corrects FV deformitie…

A Musculoskeletal Model for Estimating Hip Contact Pressure During Walking Open

Brecca M.M. Gaffney, Spencer T. Williams, Jocelyn N. Todd, Jeffrey A. Weiss, Michael D. Harris · 2022

Femoral version deformities alter joint reaction forces in dysplastic hips during gait Open

Molly C. Shepherd, Brecca M.M. Gaffney, Ke Song, John C. Clohisy, Jeffrey J. Nepple , et al. · 2022

The biomechanical disadvantage of dysplastic hips Open

Michael D. Harris, Molly C. Shepherd, Ke Song, Brecca M.M. Gaffney, Travis J. Hillen , et al. · 2021

Developmental dysplasia of the hip (DDH) is strongly associated with an increased risk for hip osteoarthritis. Skeletal deformities undeniably contribute to detrimental biomechanical loading in dysplastic hips, but cannot explain all types…

Acetabular Edge Loading During Gait Is Elevated by the Anatomical Deformities of Hip Dysplasia Open

Ke Song, Cecilia Pascual‐Garrido, John C. Clohisy, Michael D. Harris · 2021

Developmental dysplasia of the hip (DDH) is a known risk factor for articular tissue damage and secondary hip osteoarthritis. Acetabular labral tears are prevalent in hips with DDH and may result from excessive loading at the edge of the s…

Sea Otter, Enhydra lutris, mortalities in California, 1968 through 1993 Open

Christine A. Pattison, Michael D. Harris, Frederick E. Wendell · 2021

Sea otter, Enhydra lutris, mortality in California and the relative contribution from specific causes was assessed for the 26 years from 1968 through 1993. There were 2,082 dead sea otters recorded from Tomales Bay (Marin County) south to …

Clinical Signs and Pathology Associated With Domoic Acid Toxicosis in Southern Sea Otters (Enhydra lutris nereis) Open

Melissa A. Miller, Megan E. Moriarty, Pádraig J. Duignan, Tanja S. Zabka, Erin Dodd , et al. · 2021

The marine biotoxin domoic acid (DA) is an analog of the neurotransmitter glutamate that exerts potent excitatory activity in the brain, heart, and other tissues. Produced by the diatom Pseudo-nitzschia spp., DA accumulates in marine inver…

Multi-joint biomechanics during sloped walking in patients with developmental dysplasia of the hip Open

Brecca M.M. Gaffney, Linda R. Van Dillen, Jacqueline N. Foody, Paige E. Burnet, John C. Clohisy , et al. · 2021

Habitat Features Predict Carrying Capacity of a Recovering Marine Carnivore Open

M. Tim Tinker, Julie L. Yee, Kristin L. Laidre, Brian B. Hatfield, Michael D. Harris , et al. · 2021

The recovery of large carnivore species from over‐exploitation can have socioecological effects; thus, reliable estimates of potential abundance and distribution represent a valuable tool for developing management objectives and recovery c…

Effect of simulated rehabilitation on hip joint loading during single limb squat in patients with hip dysplasia Open

Brecca M.M. Gaffney, Marcie Harris‐Hayes, John C. Clohisy, Michael D. Harris · 2021

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