M. J. Duff
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Duality anomalies in linearized gravity Open
Classical linearized gravity admits a dual formulation in terms of a higher-rank tensor field. However, proposing a prescription for the instanton sectors of linearized gravity and its dual, we show that they may be . The duality anomaly i…
View article: Survival outcomes in patients with sigmoid volvulus
Survival outcomes in patients with sigmoid volvulus Open
Aim This study aimed to assess management pathways and outcomes in sigmoid volvulus (SV). Methods A retrospective review was performed on patients first admitted with SV between 2019 and 2023 within a tertiary-level colorectal service. Dem…
Kaluza-Klein Supergravity 2025 Open
We recall our work in the 1980s taking seriously the maximal eleven dimensions of supergravity, in particular the round, left squashed and right squashed $S^7$ compactifications to $D=4$ yielding $\mathcal N=8$, $\mathcal N=1$ and $\mathca…
Montonen–Olive duality of gauged supergravity? Open
The vanishing of the SO ( N ) β -function of gauged N > 4 supergravity has long seemed like an answer looking for a question. Here we conjecture that it is a consequence of a Montonen–Olive style electric/magnetic duality.
View article: <scp>IMPACT</scp> organizational survey highlighting provision of services for patients with locally advanced and recurrent colorectal cancer across Great Britain and Ireland
<span>IMPACT</span> organizational survey highlighting provision of services for patients with locally advanced and recurrent colorectal cancer across Great Britain and Ireland Open
Aim Locally advanced and recurrent colorectal cancer represents a complex clinical entity, which requires multidisciplinary decision‐making and management. The aim of this work is to understand the provision of clinical services in this co…
Montonen-Olive duality of gauged supergravity? Open
The vanishing of the SO(N) beta-function of gauged N>4 supergravity has long seemed like an answer looking for a question. Here we conjecture that it is a consequence of a Montonon-Olive style electric/magnetic duality.
View article: HIV BG505 SOSIP.664 trimer with 3M-052-AF/alum induces human autologous tier-2 neutralizing antibodies
HIV BG505 SOSIP.664 trimer with 3M-052-AF/alum induces human autologous tier-2 neutralizing antibodies Open
Stabilized trimers preserving the native-like HIV envelope structure may be key components of a preventive HIV vaccine regimen to induce broadly neutralizing antibodies (bnAbs). We evaluated trimeric BG505 SOSIP.664 gp140, formulated with …
View article: Empty pelvis syndrome: PelvEx Collaborative guideline proposal
Empty pelvis syndrome: PelvEx Collaborative guideline proposal Open
Contains fulltext : 302520.pdf (Publisher’s version ) (Open Access)
View article: Double faecal immunochemical testing in patients with symptoms suspicious of colorectal cancer
Double faecal immunochemical testing in patients with symptoms suspicious of colorectal cancer Open
Background Faecal immunochemical test (FIT)-directed pathways based on a single test have been implemented for symptomatic patients. However, with a single test, the sensitivity is 87 per cent at 10 µg haemoglobin (Hb) per g faeces. This a…
View article: Minimum standards of pelvic exenterative practice: PelvEx Collaborative guideline
Minimum standards of pelvic exenterative practice: PelvEx Collaborative guideline Open
This document outlines the important aspects of caring for patients who have been diagnosed with advanced pelvic cancer. It is primarily aimed at those who are establishing a service that adequately caters to this patient group. The releva…
Chris Isham: mentor, colleague, friend Open
Celebrating fifty years of collaboration and friendship with Chris Isham.
Sir Thomas Walter Bannerman Kibble. 23 December 1932—2 June 2016 Open
Professor Tom Kibble was an internationally-renowned theoretical physicist whose contributions to theoretical physics range from the theory of elementary particles to modern early-Universe cosmology. The unifying theme behind all his work …
View article: Induction chemotherapy followed by chemoradiotherapy <i>versus</i> chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer: study protocol of a multicentre, open-label, parallel-arms, randomized controlled study (PelvEx II)
Induction chemotherapy followed by chemoradiotherapy <i>versus</i> chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer: study protocol of a multicentre, open-label, parallel-arms, randomized controlled study (PelvEx II) Open
Background A resection with clear margins (R0 resection) is the most important prognostic factor in patients with locally recurrent rectal cancer (LRRC). However, this is achieved in only 60 per cent of patients. The aim of this study is t…
View article: Perioperative management and anaesthetic considerations in pelvic exenterations using Delphi methodology: results from the PelvEx Collaborative
Perioperative management and anaesthetic considerations in pelvic exenterations using Delphi methodology: results from the PelvEx Collaborative Open
Background The multidisciplinary perioperative and anaesthetic management of patients undergoing pelvic exenteration is essential for good surgical outcomes. No clear guidelines have been established, and there is wide variation in clinica…
Black Holes and Higher Composition Laws Open
We describe various relations between Bhargava's higher composition laws, which generalise Gauss's original composition law on integral binary quadratic forms, and extremal black hole solutions appearing in string/M-theory and related mode…
View article: Five-year oncological outcomes after selective neoadjuvant radiotherapy for resectable rectal cancer
Five-year oncological outcomes after selective neoadjuvant radiotherapy for resectable rectal cancer Open
Introduction: There is considerable variation in selection of patients for and type of neoadjuvant radiotherapy administered in the treatment of resectable rectal cancer. The aim of this study was to report outcomes for patients with resec…
The mile high magic pyramid* Open
Using a unified formulation of $\mathcal{N} = 1, 2, 4, 8$, super Yang-Mills theories in $D = 3$ spacetime dimensions with fields valued respectively in $\mathbb{R, C, H, O}$, it was shown that tensoring left and right multiplets yields a F…
Thirty years of Erice on the brane Open
After initially meeting with fierce resistance, "branes", p-dimensional extended objects which go beyond particles (p=0) and strings (p=1), now occupy centre stage in theoretical physics as microscopic components of M-theory, as the seeds …
Freudenthal duality and conformal isometries of extremal black holes Open
We present a conformal isometry for static extremal black hole solutions in all four-dimensional Einstein-Maxwell-scalar theories with electromagnetic duality groups `of type $E_7$'. This includes, but is not limited to, all supergravity t…
Gravity as Gauge Theory Squared: A Ghost Story Open
The Becchi-Rouet-Stora-Tyutin (BRST) transformations and equations of motion of a gravity-two-form-dilaton system are derived from the product of two Yang-Mills theories in a BRST covariant form, to linear approximation. The inclusion of g…
An Agent Based Model to Analyze the Effects of Traffic Signal Timing on Vehicle Throughput in Inclement Weather Open
This preliminary paper discusses the creation of an agent based model for a signalized traffic intersection derived from a previously developed mathematical vehicle-following micro-simulation model.The results of the agent based model are …
Twin supergravities from Yang-Mills theory squared Open
We consider “twin supergravities”—pairs of supergravities with N + and N − supersymmetries, N + > N − , with identical bosonic sectors—in the context of tensoring super Yang-Mills multiplets. It is demonstrated that the pairs of twin super…
View article: Protocol for a multicentre randomised feasibility trial evaluating early Surgery Alone In LOw Rectal cancer (SAILOR)
Protocol for a multicentre randomised feasibility trial evaluating early Surgery Alone In LOw Rectal cancer (SAILOR) Open
Introduction There are 11 500 rectal cancers diagnosed annually in the UK. Although surgery remains the primary treatment, there is evidence that preoperative radiotherapy (RT) improves local recurrence rates. High-quality surgery in recta…
A novel treatment approach prolonging survival in an uncommon metastatic primary bladder adenocarcinoma Open
Primary bladder adenocarcinoma (PBA) is an epithelial malignancy with pure glandular differentiation, without evidence of typical urothelial (transitional cell) carcinoma. PBA is rare, accounting for 0.5%-2% of all malignant bladder neopla…