Michael E. Divine
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View article: A functional screen for ubiquitin regulation identifies an E3 ligase secreted by<i>Pseudomonas aeruginosa</i>
A functional screen for ubiquitin regulation identifies an E3 ligase secreted by<i>Pseudomonas aeruginosa</i> Open
Ubiquitin signaling controls many aspects of eukaryotic biology, including targeted protein degradation and immune defense. Remarkably, invading bacterial pathogens have adapted secreted effector proteins that hijack host ubiquitination to…
View article: Interplay between septins and ubiquitin-mediated xenophagy during <i>Shigella</i> entrapment
Interplay between septins and ubiquitin-mediated xenophagy during <i>Shigella</i> entrapment Open
Septins are cytoskeletal proteins implicated in numerous cellular processes including cytokinesis and morphogenesis. In the case of infection by Shigella flexneri, septins assemble into cage-like structures that entrap cytosolic bac…
View article: Septins and K63 ubiquitin chains are present in separate bacterial microdomains during autophagy of entrapped <i>Shigella</i>
Septins and K63 ubiquitin chains are present in separate bacterial microdomains during autophagy of entrapped <i>Shigella</i> Open
During host cell invasion, Shigella escapes to the cytosol and polymerizes actin for cell-to-cell spread. To restrict cell-to-cell spread, host cells employ cell-autonomous immune responses including antibacterial autophagy and septin cage…
View article: Septins and K63 chains form separate bacterial microdomains during autophagy of entrapped<i>Shigella</i>
Septins and K63 chains form separate bacterial microdomains during autophagy of entrapped<i>Shigella</i> Open
During host cell invasion, Shigella escapes to the cytosol and polymerizes actin for cell-to-cell spread. To restrict cell-to-cell spread, host cells employ cell-autonomous immune responses including antibacterial autophagy and septin cage…