Michael E. Dolch
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Point‐of‐care breath sample analysis by semiconductor‐based E‐Nose technology discriminates non‐infected subjects from SARS‐CoV‐2 pneumonia patients: a multi‐analyst experiment Open
Metal oxide sensor‐based electronic nose (E‐Nose) technology provides an easy to use method for breath analysis by detection of volatile organic compound (VOC)‐induced changes of electrical conductivity. Resulting signal patterns are then …
Identification of microRNA biomarkers simultaneously expressed in circulating extracellular vesicles and atherosclerotic plaques Open
Background Atherosclerosis is a widespread disorder of the cardiovascular system. The early detection of plaques by circulating biomarkers is highly clinically relevant to prevent the occurrence of major complications such as stroke or hea…
Exhaled Breath and Oxygenator Sweep Gas Propionaldehyde in Acute Respiratory Distress Syndrome Open
Background: Oxidative stress-induced lipid peroxidation (LPO) due to neutrophil-derived reactive oxygen species plays a key role in the early stage of the acute respiratory distress syndrome (ARDS). Monitoring of oxidative stress in this p…
Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia Open
Introduction Hip fracture surgery is associated with high in-hospital and 30-day mortality rates and serious adverse patient outcomes. Evidence from randomised controlled trials regarding effectiveness of spinal versus general anaesthesia …