Michael E. Scheurer
YOU?
Author Swipe
View article: Supplemental Table 1 from Polymorphisms in the Nonhomologous End-joining DNA Repair Pathway are Associated with HPV Integration in Cervical Dysplasia
Supplemental Table 1 from Polymorphisms in the Nonhomologous End-joining DNA Repair Pathway are Associated with HPV Integration in Cervical Dysplasia Open
Supplemental Table 1: Tag SNPs and Calculated Odds Ratios
View article: Supplemental Table 2 from Polymorphisms in the Nonhomologous End-joining DNA Repair Pathway are Associated with HPV Integration in Cervical Dysplasia
Supplemental Table 2 from Polymorphisms in the Nonhomologous End-joining DNA Repair Pathway are Associated with HPV Integration in Cervical Dysplasia Open
Supplemental Table 2: Integration assay primer and probe sequences
View article: Outcome disparities among survivors of hematologic malignancies diagnosed in childhood
Outcome disparities among survivors of hematologic malignancies diagnosed in childhood Open
Introduction: Latinos are a rapidly growing population in the Southwest U.S. Evidence has suggested population-based differences in childhood cancer outcomes, but studies and cohorts that inform both late effects risk and survivorship prac…
View article: NCOG-48. Level of Resection Predicts Deficits in Psychosocial and Executive Functioning in Pediatric Brain Tumor Survivors Treated with Surgery Only
NCOG-48. Level of Resection Predicts Deficits in Psychosocial and Executive Functioning in Pediatric Brain Tumor Survivors Treated with Surgery Only Open
Pediatric brain tumor survivors are known to be at risk for long-term deficits in psychosocial and executive functioning. Few studies focus on patients treated with surgery alone, with sparsely reported long-term outcomes. We aimed to char…
View article: The impact of Indigenous American-like ancestry on the risk of acute lymphoblastic leukemia in Hispanic/Latino children
The impact of Indigenous American-like ancestry on the risk of acute lymphoblastic leukemia in Hispanic/Latino children Open
View article: Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci
Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci Open
View article: Figure S4. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study
Figure S4. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study Open
Density of study subjects in Minnesota census tracts. The top map represents density of cases and controls combined, while the lower left and lower right represent density of only controls and only cases, respectively.
View article: Figure S5. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study
Figure S5. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study Open
High and low average air pollution measured as the average of PM2.5 (µg/m3) and NDVI by cancer types, stratified by trimesters. Panel A: PM2.5 exposure; values < 12.0 µg/m3 were categorized as low and ≥12.0 were categorized as high. Panel …
View article: Figure S1. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study
Figure S1. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study Open
Seasonal and annual variability in PM2.5 (µg/m3) exposure levels estimated in the study population. Box plots represent the distribution of estimated ambient air pollution exposures for births falling within each month and year.
View article: Table S1. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study
Table S1. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study Open
PM2.5 and NDVI exposure distribution between cases and controls per pregnancy period.
View article: Table S3. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study
Table S3. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study Open
Odds ratios (OR) and 95% confidence intervals (CI) for the association between an interquartile range increase in PM2.5 and childhood cancer risk, per pregnancy period: census tract SES adjusted.
View article: Table S2. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study
Table S2. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study Open
Odds ratios (OR) and 95% confidence intervals (CI) for the association between an interquartile range increase in PM2.5 and childhood cancer risk, per pregnancy period, mutually adjusted for NDVI.
View article: Table S5. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study
Table S5. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study Open
Odds ratios (OR) and 95% confidence intervals (CI) for the association between an interquartile range increase in average normalized difference vegetation index (NDVI) and childhood cancer risk, per pregnancy period, mutually adjusted for …
View article: Figure S3. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study
Figure S3. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study Open
Annual maps of mean estimated NDVI values in Minnesota census tracts for the study period of 2000-2014. NDVI levels represent the average census tract-level exposure for study subjects in that tract during that year.
View article: Figure S2. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study
Figure S2. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study Open
Annual maps of mean estimated PM2.5 values in Minnesota census tracts for the study period of 2000-2014. PM2.5 concentrations given in µg/m3 represent the average census tract-level exposure for study subjects in that tract during that yea…
View article: Table S4. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study
Table S4. from Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case–Control Study Open
Odds ratios (OR) and 95% confidence intervals (CI) for the association between an interquartile range increase in the average normalized difference vegetation index (NDVI) and childhood cancer risk, per pregnancy period.
View article: Ubiquitous dysregulation of the Wnt pathway in immune thrombocytopenia genetic susceptibility
Ubiquitous dysregulation of the Wnt pathway in immune thrombocytopenia genetic susceptibility Open
The pathogenesis of immune thrombocytopenia (ITP) is complex and incompletely understood. Multiple cell types have been implicated, and their respective contribution is unclear. A recent genome-wide association study identified single-nucl…
View article: Fluid Assessment Scoring Tool (FAST): Development of a Novel Fluid Assessment Scoring Tool for Critically Ill Pediatric Patients—A Pilot Study
Fluid Assessment Scoring Tool (FAST): Development of a Novel Fluid Assessment Scoring Tool for Critically Ill Pediatric Patients—A Pilot Study Open
View article: Detecting hidden threats using longitudinal liquid biopsies
Detecting hidden threats using longitudinal liquid biopsies Open
Multicancer early detection (MCED) assays aim to detect cancers while still asymptomatic and, hopefully, more likely to be curable. To understand how long an MCED assay is interpretable before the emergence of symptoms and how frequently t…
View article: An analysis of diagnostic metabolomic profiles associated with hepatotoxicity during childhood ALL induction therapy
An analysis of diagnostic metabolomic profiles associated with hepatotoxicity during childhood ALL induction therapy Open
Hepatotoxicity is a well-documented complication of induction chemotherapy for acute lymphoblastic leukemia (ALL), but our understanding of its biological mechanisms is limited. We identified 314 patients with ALL (aged 1-19 years) treated…
View article: Extraction-free RT-RPA assay for detection of HPV16, HPV18, and HPV45 mRNA expression
Extraction-free RT-RPA assay for detection of HPV16, HPV18, and HPV45 mRNA expression Open
Messenger RNA (mRNA) from high-risk genotypes of human papillomavirus (hrHPV) is a more specific biomarker for cervical cancer risk than hrHPV DNA due to its ability to differentiate clinically significant infections from transient ones. D…
View article: Predictors of response to emergent therapies in paediatric immune thrombocytopenia
Predictors of response to emergent therapies in paediatric immune thrombocytopenia Open
Summary Emergent therapies (ET), which include intravenous immunoglobulin (IVIG), corticosteroids and intravenous anti‐Rho(D) immunoglobulin, are used to treat acute episodes of bleeding in children with immune thrombocytopenia (ITP). Ther…
View article: Table S6 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma
Table S6 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma Open
METRO-Egger results from African American (AA), Hispanic/Latino (MX), and European (EA) ancestries at 500kb clumping physical distance thresholds. (contains p-value, heritabilities and Fisher p-value)
View article: Table S5 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma
Table S5 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma Open
METRO results from African American (AA), Hispanic/Latino (MX), and European (EA) ancestries at 500kb clumping physical distance thresholds. (contains p-value, heritabilities and Fisher p-value)
View article: Table S2 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma
Table S2 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma Open
METRO results from African American (AA), Hispanic/Latino (MX), and European (EA) ancestries at 250kb clumping physical distance thresholds. (contains p-value, heritabilities and Fisher p-value)
View article: Figure S9 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma
Figure S9 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma Open
Plotted differential expression of normalized gene counts for the top 6 down-regulated genes by Log2 fold changes (LFC) for the Japanese HB cohort.
View article: Figure S6 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma
Figure S6 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma Open
Manhattan plots of METRO-Egger analysis at 500kb
View article: Figure S5 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma
Figure S5 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma Open
Manhattan plots of METRO analysis at 500kb
View article: Figure S7 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma
Figure S7 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma Open
Plots comparing the effect of imputed gene expression on hepatoblastoma risk by METRO and METRO-Egger Analysis (500kb)
View article: Data from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma
Data from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma Open
Background:Hepatoblastoma (HB) is a rare embryonal liver tumor, with an increasing global incidence that underscores the need to understand its genetic etiology.Methods:Utilizing the ancestry-matched expression quantitative loci data, we p…