Michael Fries
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View article: Comprehensive analysis and prediction of long-term durability of factor IX activity following etranacogene dezaparvovec gene therapy in the treatment of hemophilia B
Comprehensive analysis and prediction of long-term durability of factor IX activity following etranacogene dezaparvovec gene therapy in the treatment of hemophilia B Open
People with hemophilia B receiving etranacogene dezaparvovec would likely achieve durable FIX activity levels and remain free of prophylactic FIX replacement products for up to 25.5 years following single administration. The long-term fact…
View article: Implementation of anesthesia quality indicators in Germany
Implementation of anesthesia quality indicators in Germany Open
Background In 2016 the German Society of Anesthesiology and Intensive Care Medicine (DGAI) and the Association of German Anesthetists (BDA) published 10 quality indicators (QI) to compare and improve the quality of anesthesia care in Germa…
View article: Safety of biweekly α<sub>1</sub>-antitrypsin treatment in the RAPID programme
Safety of biweekly α<sub>1</sub>-antitrypsin treatment in the RAPID programme Open
Administration of 120 mg·kg(−1) α(1)-antitrypsin on a biweekly basis was safe and well tolerated http://ow.ly/CVbz30lUBum
View article: The Effect of Alpha-1 Proteinase Inhibitor on Biomarkers of Elastin Degradation in Alpha-1 Antitrypsin Deficiency: An Analysis of the RAPID/RAPID Extension Trials
The Effect of Alpha-1 Proteinase Inhibitor on Biomarkers of Elastin Degradation in Alpha-1 Antitrypsin Deficiency: An Analysis of the RAPID/RAPID Extension Trials Open
The RAPID (NCT00261833; N=180) and RAPID Extension (NCT00670007; N=140) trials demonstrated significantly reduced lung density decline in patients with alpha-1 antitrypsin deficiency (AATD) receiving alpha-1 proteinase inhibitor (A1PI) ver…
View article: Evaluation of a wireless activity monitoring system to quantify locomotor activity in horses in experimental settings
Evaluation of a wireless activity monitoring system to quantify locomotor activity in horses in experimental settings Open
Summary Reasons for performing study Methods of evaluating locomotor activity can be useful in efforts to quantify behavioural activity in horses objectively. Objectives To evaluate whether an accelerometric device would be adequate to qua…