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Postoperative Radiotherapy of Prostate Cancer: Adjuvant versus Early Salvage Open

Daniel Wegener, Daniel M. Aebersold, Marc‐Oliver Grimm, Peter Hammerer, Michael Froehner , et al. · 2022

Results of three randomized clinical trials (RCTs) comparing adjuvant radiotherapy (ART) and early salvage radiotherapy (eSRT) of prostate carcinoma and a subsequent meta-analysis of the individual patient data from these RCTs were recentl…

How Well do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis Open

Aino Siltari, Ragnar Lönnerbro, Karl H. Pang, Кирилл Ширанов, Alex Asiimwe , et al. · 2022

Typically, PRS accuracy is comparable to PSA or family history with a pooled AUC value 0.63 indicating mediocre performance for PRS alone.

Table of Contents Open

Modern Gynecology, Megan Prunty, Laura Bukavina, J Hallman, Oluwarotimi Nettey , et al. · 2021

The Key Role of Patient Involvement in the Development of Core Outcome Sets in Prostate Cancer Open

Katharina Beyer, Sara MacLennan, Lisa Moris, Michael Lardas, Ken Mastris , et al. · 2021

Patients are the stewards of their own care and hence their voice is important when designing and implementing research. Patients should be involved not only as participants in research that impacts their care, as the recipients of that ca…

Defining a Standard Set of Patient-centered Outcomes for Men with Localized Prostate Cancer Open

Neil A. Martin, Laura Massey, Caleb Stowell, Chris Bangma, Alberto Briganti , et al. · 2021

Background: Value-based health care has been proposed as a unifying force to drive improved outcomes and cost containment. Objective: To develop a standard set of multidimensional patient-centered health outcomes for tracking, comparing, a…

Decreasing Non–bladder-cancer Mortality After Radical Cystectomy Open

Michael Froehner, Rainer Koch, Ulrike Heberling, Angelika Borkowetz, Matthias Hübler , et al. · 2021

PSMA PET Before and After Initial Long Term Androgen Deprivation in Patients With Newly Diagnosed Prostate Cancer Open

Sebastian Hoberück, Steffen Löck, Robert Winzer, Klaus Zöphel, Michael Froehner , et al. · 2020

Purpose: The study aimed to evaluate the effect of androgen deprivation therapy (ADT) on PSMA imaging and its correlation to the PSA concentration comparing qualitative and quantitative parameters: SUVmax, SUVmean, PSMA-derived tumor volum…

Extraadrenal pheochromocytoma masquerading as renal tumor Open

Anne-Kathrin Sünder, Uta Stiller, Jörg Wittmann, Michael Froehner · 2020

Urinary MicroRNAs as Potential Markers for Non-Invasive Diagnosis of Bladder Cancer Open

Kati Erdmann, Karsten Salomo, Anna Klimová, Ulrike Heberling, Andrea Lohse-Fischer , et al. · 2020

Currently, voided urine cytology (VUC) serves as the gold standard for the detection of bladder cancer (BCa) in urine. Despite its high specificity, VUC has shortcomings in terms of sensitivity. Therefore, alternative biomarkers are being …

Radical Prostatectomy versus External Beam Radiotherapy - Indication and the Way to the Decision: A Cumulative Non-Interventional Unicentric Retrospective Trial of about 20 Years Open

Boehm Wolf-Diether U, Rainer Koch, Michael Froehner, Wenzel Stefanie, Werner Carmen , et al. · 2020

From the clinical reality of a private consultation, a non-interventional, parallel, two-armed, non-randomized study was started in close cooperation with the Regional Clinical Cancer Register Dresden for the period 1996-2016, in order to …

Validation of a Questionnaire-Suitable Comorbidity Index in Patients Undergoing Radical Cystectomy Open

Michael Froehner, Rainer Koch, Ulrike Heberling, Angelika Borkowetz, Matthias Hübler , et al. · 2020

Objective: To investigate the capability of a modified self-administrable comorbidity index recommended in the standard sets for neoplastic diseases published by the International Consortium for Health Outcomes Measurement (I…

Supplementary Material for: Validation of a Questionnaire-Suitable Comorbidity Index in Patients Undergoing Radical Cystectomy Open

Michael Froehner, R. Koch, Ulrike Heberling, Angelika Borkowetz, M. Hübler , et al. · 2020

Objective: To investigate the capability of a modified self-administrable comorbidity index recommended in the standard sets for neoplastic diseases published by the International Consortium for Health Outcomes Measurement (I…

PD25-09 PREDICTORS OF LONG-TERM MORTALITY IN PATIENTS WITH POSITIVE LYMPH NODES AT RADICAL PROSTATECTOMY Open

Ulrike Heberling, Rainer Koch, Angelika Borkowetz, Gustavo Baretton, Manfred P. Wirth , et al. · 2019

4) Exercise barriers.Participants reported time management and fatigue as main exercise barriers.Moreover, they expressed the concern to be judged for their physical appearance and performance when exercising in groups.CONCLUSIONS: These f…

PD40-07 VALIDATION OF AN EASILY APPLICABLE QUESTIONNAIRE-SUITED COMORBIDITY INDEX IN 5050 CONSECUTIVE PATIENTS UNDERGOING RADICAL PROSTATECTOMY Open

Michael Froehner, Ulrike Heberling, Christoph Heitmann, Samaneh Farahzadi, Marcus Lindner , et al. · 2019

You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy I (PD40)1 Apr 2019PD40-07 VALIDATION OF AN EASILY APPLICABLE QUESTIONNAIRE-SUITED COMORBIDITY INDEX IN 5050 CONSECUTIVE PATIENTS UNDERGOING RADICAL PROSTATECTOMY…

Supplementary Material for: Socioeconomic Status-Related Parameters as Predictors of Competing (Non-Bladder Cancer) Mortality after Radical Cystectomy Open

Michael Froehner, David Muallah, R. Koch, M. Hübler, Angelika Borkowetz , et al. · 2019

Objective: To investigate the impact of socioeconomic status-related parameters on competing (non-bladder cancer) mortality after radical cystectomy. Patients and Methods: A total of 1,268 consecutive patients w…

Leiomyosarcoma of the Urinary Bladder in Adult Patients: A Systematic Review of the Literature and Meta-Analysis Open

Helen Zieschang, Rainer Koch, Manfred P. Wirth, Michael Froehner · 2018

Purpose: Leiomyosarcoma of the urinary bladder is exceedingly rare. Most clinicians come across only a few cases during their career, and information regarding treatment and outcome is scattered in the scientific literature. …

Predicting 90-day and long-term mortality in octogenarians undergoing radical cystectomy Open

Michael Froehner, Rainer Koch, Matthias Hübler, Ulrike Heberling, Vladimír Novotný , et al. · 2018

Systematic Review of Comorbidity and Competing-risks Assessments for Bladder Cancer Patients Open

Stephen B. Williams, Ashish M. Kamat, Karim Chamie, Michael Froehner, Manfred P. Wirth , et al. · 2018

MP12-04 ONLY LESS THAN 10% OF PATIENTS SELECTED FOR RADICAL PROSTATECTOMY REACH THE COMPETING MORTALITY RATE OF THE PROSTATE CANCER INTERVENTION VERSUS OBSERVATION TRIAL (PIVOT) Open

Michael Froehner, Rainer Koch, Matthias Hübler, Theresa Renner, Angelika Borkowetz , et al. · 2018

You have accessJournal of UrologyProstate Cancer: Localized: Active Surveillance I1 Apr 2018MP12-04 ONLY LESS THAN 10% OF PATIENTS SELECTED FOR RADICAL PROSTATECTOMY REACH THE COMPETING MORTALITY RATE OF THE PROSTATE CANCER INTERVENTION VE…

MP57-12 PREDICTION OF CLINICALLY SIGNIFICANT PROSTATE CANCER IN PATIENTS WITH PREVIOUSLY NEGATIVE PROSTATE BIOPSY UNDERGOING MRI/ULTRASOUND-FUSION BIOPSY IN COMBINATION WITH SYSTEMATIC BIOPSY Open

Angelika Borkowetz, Theresa Renner, Ivan Platzek, Marieta Toma, Michael Froehner , et al. · 2018

You have accessJournal of UrologyProstate Cancer: Detection & Screening V1 Apr 2018MP57-12 PREDICTION OF CLINICALLY SIGNIFICANT PROSTATE CANCER IN PATIENTS WITH PREVIOUSLY NEGATIVE PROSTATE BIOPSY UNDERGOING MRI/ULTRASOUND-FUSION BIOPSY IN…

MP20-20 BETTER PREDICTION OF TUMOR AGGRESSIVENESS IN MRI/ULTRASOUND-FUSION-BIOPSY COMPARED TO SYSTEMATIC PROSTATE BIOPSY Open

Angelika Borkowetz, Ivan Platzek, Marieta Toma, Theresa Renner, Michael Froehner , et al. · 2018

You have accessJournal of UrologyImaging/Radiology: Uroradiology II1 Apr 2018MP20-20 BETTER PREDICTION OF TUMOR AGGRESSIVENESS IN MRI/ULTRASOUND-FUSION-BIOPSY COMPARED TO SYSTEMATIC PROSTATE BIOPSY Angelika Borkowetz, Ivan Platzek, Marieta…

MP29-12 ASSOCIATION OF NEUROPILIN 2 AND EGFR CO-EXPRESSION WITH CANCER-SPECIFIC SURVIVAL IN PROSTATE CANCER AND THE INFLUENCE OF NEUROPILIN 2-DEPLETION COMBINED WITH EGFR-INHIBITION ON CELL FUNCTIONING IN CISPLATIN-SENSITIVE AND –RESISTANT DU145 PROSTATE CANCER CELL LINES Open

Angelika Borkowetz, Susanne Fuessel, Kati Erdmann, Alexander Schulz, Marieta Toma , et al. · 2018

You have accessJournal of UrologyProstate Cancer: Basic Research & Pathophysiology I1 Apr 2018MP29-12 ASSOCIATION OF NEUROPILIN 2 AND EGFR CO-EXPRESSION WITH CANCER-SPECIFIC SURVIVAL IN PROSTATE CANCER AND THE INFLUENCE OF NEUROPILIN 2-DEP…

Adjuvant radiotherapy and mortality in lymph node-positive prostate cancer Open

Michael Froehner, Manfred P. Wirth · 2018

In a retrospective study, Touijer and co-workers investigated mortality in 1,338 patients with lymph-node positive prostate cancer who underwent radical prostatectomy between 1988 and 2010 in two centers in the US and one in Italy (1).

Supplementary Material for: Leiomyosarcoma of the Urinary Bladder in Adult Patients: A Systematic Review of the Literature and Meta-Analysis Open

Helen Zieschang, R. Koch, Manfred P. Wirth, Michael Froehner · 2018

Purpose: Leiomyosarcoma of the urinary bladder is exceedingly rare. Most clinicians come across only a few cases during their career, and information regarding treatment and outcome is scattered in the scientific literature. …

Gender and Mortality after Radical Cystectomy: Competing Risk Analysis Open

Ulrike Heberling, Rainer Koch, Matthias Hübler, Gustavo Baretton, Oliver W. Hakenberg , et al. · 2018

Background: Data on the impact of gender on mortality after radical cystectomy is conflicting. We investigated a large single center sample with long-term follow-up in order to determine the relationship between gender and ou…

Evaluation of Magnetic Resonance Imaging/Ultrasound-Fusion Biopsy in Patients with Low-Risk Prostate Cancer Under Active Surveillance Undergoing Surveillance Biopsy Open

Angelika Borkowetz, Theresa Renner, Ivan Platzek, Marieta Toma, Roman Herout , et al. · 2018

Introduction: Targeted biopsy of tumour-suspicious lesions detected in multiparametric magnetic resonance imaging (mpMRI) plays an increasing role in the active surveillance (AS) of patients with low-risk prostate cancer (PCa…

Prospective comparison of transperineal magnetic resonance imaging/ultrasonography fusion biopsy and transrectal systematic biopsy in biopsy‐naïve patients Open

Angelika Borkowetz, Boris Hadaschik, Ivan Platzek, Marieta Toma, Georgi Torsev , et al. · 2017

Objectives To evaluate the value of multiparametric magnetic resonance imaging (mp MRI ) in the detection of significant prostate cancer ( PC a) and to compare transperineal MRI /ultrasonography fusion biopsy (fusPbx) with conventional tra…

Urinary transcript quantitation of CK20 and IGF2 for the non-invasive bladder cancer detection Open

Karsten Salomo, Doreen Huebner, M. Boehme, Alexander Herr, Werner Brabetz , et al. · 2017

MP21-07 SELECTION EFFECTS MAY EXPLAIN SMOKING-RELATED OUTCOME DIFFERENCES AFTER RADICAL CYSTECTOMY Open

Michael Froehner, Rainer Koch, Matthias Hübler, Ulrike Heberling, Vladimír Novotný , et al. · 2017

You have accessJournal of UrologyBladder Cancer: Invasive I1 Apr 2017MP21-07 SELECTION EFFECTS MAY EXPLAIN SMOKING-RELATED OUTCOME DIFFERENCES AFTER RADICAL CYSTECTOMY Michael Froehner, Rainer Koch, Matthias Hübler, Ulrike Heberling, Vladi…

Evaluation of Prostate Imaging Reporting and Data System Classification in the Prediction of Tumor Aggressiveness in Targeted Magnetic Resonance Imaging/Ultrasound-Fusion Biopsy Open

Angelika Borkowetz, Ivan Platzek, Marieta Toma, Theresa Renner, Roman Herout , et al. · 2017

Objectives: The study aimed to evaluate the prediction of Prostate Imaging Reporting and Data System (PI-RADS) with respect to the prostate cancer (PCa) detection rate and tumor aggressiveness in magnetic resonance imaging (M…

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