Michael Glogauer
YOU?
Author Swipe
View article: Pathways of neutrophil enzymatic degradation of resin-based composites and adhesives
Pathways of neutrophil enzymatic degradation of resin-based composites and adhesives Open
Human neutrophils (HN), white blood cells of the innate immune system, are abundant inhabitants of the oral cavity. It was previously found that these leukocytes can degrade methacrylate resin-based composites (RC), adhesives, monomers, an…
View article: Engineering bone repair with K21-Infused brushite cement: In-vitro and in-vivo insights
Engineering bone repair with K21-Infused brushite cement: In-vitro and in-vivo insights Open
Bone graft failures are often linked to infection and inflammation. Incorporating K21 into brushite cement offers a dual-action material that not only supports bone regeneration but also reduces microbial risk and inflammatory complication…
View article: Sensitivity to change of the COVID-19 anxiety syndrome scale among Canadian dentists
Sensitivity to change of the COVID-19 anxiety syndrome scale among Canadian dentists Open
View article: Comprehensive safety assessment of the probiotic Streptococcus salivarius OSTIA SALI-10
Comprehensive safety assessment of the probiotic Streptococcus salivarius OSTIA SALI-10 Open
Rigid safety protocols are essential for the development of safe therapeutic agents, including probiotics. With the growing interest in probiotic use for oral health, it is crucial that these beneficial microorganisms adhere to stringent s…
View article: DePerio: Deep Learning‐Based Oral Inflammatory Load Quantification for Periodontal Applications
DePerio: Deep Learning‐Based Oral Inflammatory Load Quantification for Periodontal Applications Open
Periodontal disease (PD) is a chronic condition associated with systemic risks like cardiovascular disease and diabetes. Traditional diagnostics detect advanced PD but often miss early‐stage cases, where timely intervention is critical. Or…
View article: Prognostic utility of oral neutrophil counts in high‐risk periodontitis: A retrospective study
Prognostic utility of oral neutrophil counts in high‐risk periodontitis: A retrospective study Open
Background Oral polymorphonuclear neutrophil (oPMN) levels are potential biomarkers for differentiating between stages and grades of periodontitis. We compared the diagnostic utility of oPMN levels with bleeding on probing percentage (BOP%…
View article: Deep Learning for Detecting Dental Plaque and Gingivitis From Oral Photographs: A Systematic Review
Deep Learning for Detecting Dental Plaque and Gingivitis From Oral Photographs: A Systematic Review Open
Objectives This systematic review aimed to evaluate the performance of deep learning (DL) models in detecting dental plaque and gingivitis from red, green, and blue (RGB) intraoral photographs. Methods A comprehensive literature search was…
View article: Hyperfunctional Neutrophils in Aged Mice Are Linked to Enhanced Bone Loss in Ligature-Induced Periodontitis
Hyperfunctional Neutrophils in Aged Mice Are Linked to Enhanced Bone Loss in Ligature-Induced Periodontitis Open
Background/Objectives: Aging alters neutrophil functions, which may contribute to the progression and severity of periodontitis-related alveolar bone loss. Neutrophils play a key role in immune defense. However, the effects of aging on neu…
View article: Antibiofilm properties of 4-hydroxy-3-methyl-2-alkenylquinoline, a novel <i>Burkholderia</i> -derived alkaloid
Antibiofilm properties of 4-hydroxy-3-methyl-2-alkenylquinoline, a novel <i>Burkholderia</i> -derived alkaloid Open
Biofilms are an important colonization mechanism employed by several microbial species to better establish themselves and monopolize the acquisition of resources across different environs. Some bacteria have evolved specialized metabolites…
View article: Pathways of Neutrophil Enzymatic Degradation of Resin-Based Composites and Adhesives
Pathways of Neutrophil Enzymatic Degradation of Resin-Based Composites and Adhesives Open
View article: Abstract 170: A Correlation Between Intracranial Aneurysm and Immunoinflammatory Status with the Imaging Characteristics of Periodontitis
Abstract 170: A Correlation Between Intracranial Aneurysm and Immunoinflammatory Status with the Imaging Characteristics of Periodontitis Open
IIntroduction/Purpose Intracranial aneurysms (IAs) are abnormal vascular dilations that often result in severe intracranial bleeding, contributing to morbidity and mortality worldwide. It is believed that IA development, growth, and ruptur…
View article: Impact of Postoperative Neck Radiotherapy Volumes on Long‐Term Unstimulated Saliva Flow Following Primary Surgery and Ipsilateral Neck Dissection for Oral Cavity Squamous Cell Carcinoma
Impact of Postoperative Neck Radiotherapy Volumes on Long‐Term Unstimulated Saliva Flow Following Primary Surgery and Ipsilateral Neck Dissection for Oral Cavity Squamous Cell Carcinoma Open
Background We investigate the association of postoperative radiotherapy (PORT) volumes and salivary function in oral cavity SCC (OSCC). Methods OSCC patients undergoing PORT 2005–2021 underwent modified Schirmer test (MST) pre‐PORT, 6 and/…
View article: Characterisation of myeloid cells in circulation and synovial fluid of patients with psoriatic arthritis
Characterisation of myeloid cells in circulation and synovial fluid of patients with psoriatic arthritis Open
Objective Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Adding to studies focused on the role of T cells and macrophages, we sought to investigate the systemic activation of leukocytes in PsA. Methods We…
View article: Toward Digital Periodontal Health: Recent Advances and Future Perspectives
Toward Digital Periodontal Health: Recent Advances and Future Perspectives Open
Periodontal diseases, ranging from gingivitis to periodontitis, are prevalent oral diseases affecting over 50% of the global population. These diseases arise from infections and inflammation of the gums and supporting bones, significantly …
View article: Utilizing Oral Neutrophil Counts as an Indicator of Oral Inflammation Associated With Periodontal Disease: A Blinded Multicentre Study
Utilizing Oral Neutrophil Counts as an Indicator of Oral Inflammation Associated With Periodontal Disease: A Blinded Multicentre Study Open
Background Periodontal diseases are chronic inflammatory conditions that require early screening for effective long‐term management. Oral neutrophil counts (ONCs) correlate with periodontal inflammation. This study investigates a point‐of‐…
View article: Prognosing post-treatment outcomes of head and neck cancer using structured data and machine learning: A systematic review
Prognosing post-treatment outcomes of head and neck cancer using structured data and machine learning: A systematic review Open
Background This systematic review aimed to evaluate the performance of machine learning (ML) models in predicting post-treatment survival and disease progression outcomes, including recurrence and metastasis, in head and neck cancer (HNC) …
View article: Sensitivity to change of the COVID-19 Anxiety Syndrome Scale among Canadian dentists
Sensitivity to change of the COVID-19 Anxiety Syndrome Scale among Canadian dentists Open
Introduction: There is a need to further validate the COVID-19 Anxiety Syndrome Scale (C-19ASS) by evaluating its sensitivity to change over time. Aim To estimate the sensitivity to change over time of the C-19ASS in a sample of Canadian d…
View article: Mitochondrial perturbations in low-protein-diet-fed mice are associated with altered neutrophil development and effector functions
Mitochondrial perturbations in low-protein-diet-fed mice are associated with altered neutrophil development and effector functions Open
Severe malnutrition is associated with infections, namely lower respiratory tract infections (LRTIs), diarrhea, and sepsis, and underlies the high risk of morbidity and mortality in children under 5 years of age. Dysregulations in neutroph…
View article: CBCT in Dental Implantology: A Key Tool for Preventing Peri-Implantitis and Enhancing Patient Outcomes
CBCT in Dental Implantology: A Key Tool for Preventing Peri-Implantitis and Enhancing Patient Outcomes Open
(1) Introduction: Trust is a cornerstone of the patient–physician relationships. Unforeseen complications in the health care system could jeopardize patients’ trust in their physicians. (2) Aim: This article presents a quantitative figure …
View article: Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation of a Risk-Based Model
Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation of a Risk-Based Model Open
PURPOSE Osteoradionecrosis of the jaw (ORN) can manifest in varying severity. The aim of this study is to identify ORN risk factors and develop a novel classification to depict the severity of ORN. METHODS Consecutive patients with head an…
View article: The dental COVID‐19 paradox: Disparity in behaviors inside and outside dental schools in Canada
The dental COVID‐19 paradox: Disparity in behaviors inside and outside dental schools in Canada Open
Objective To describe the personal and professional behavior and assess the perceptions of protection and fear of contracting coronavirus disease 2019 (COVID‐19) among faculty, staff, and students from all 10 Canadian dental schools during…
View article: Three-Dimensional Printing Methods for Bioceramic-Based Scaffold Fabrication for Craniomaxillofacial Bone Tissue Engineering
Three-Dimensional Printing Methods for Bioceramic-Based Scaffold Fabrication for Craniomaxillofacial Bone Tissue Engineering Open
Three-dimensional printing (3DP) technology has revolutionized the field of the use of bioceramics for maxillofacial and periodontal applications, offering unprecedented control over the shape, size, and structure of bioceramic implants. I…
View article: Investigating the perceptions and experiences of Canadian dentists on dental regulatory bodies' communications and guidelines during the <scp>COVID</scp>‐19 pandemic
Investigating the perceptions and experiences of Canadian dentists on dental regulatory bodies' communications and guidelines during the <span>COVID</span>‐19 pandemic Open
Objective Dental regulatory bodies aim to ensure the health and safety of dentists, dental staff patients and the public. An important responsibility during a pandemic is to communicate risk and guidelines for patient care. Limited data ex…
View article: A metabolic perspective of the neutrophil life cycle: new avenues in immunometabolism
A metabolic perspective of the neutrophil life cycle: new avenues in immunometabolism Open
Neutrophils are the most abundant innate immune cells. Multiple mechanisms allow them to engage a wide range of metabolic pathways for biosynthesis and bioenergetics for mediating biological processes such as development in the bone marrow…
View article: The unrevealed links: periodontal health, human milk composition, and infant gut microbiome dynamics
The unrevealed links: periodontal health, human milk composition, and infant gut microbiome dynamics Open
Aim: This review aims to identify the mechanistic relationships related to periodontal diseases and its possible association with changes in human milk composition and the composition and function of infants’ gut microbiome. Background: Ma…
View article: Mitochondrial Perturbations in Malnutrition-Associated Inflammation are Associated with Altered Neutrophil Development and Effector Functions
Mitochondrial Perturbations in Malnutrition-Associated Inflammation are Associated with Altered Neutrophil Development and Effector Functions Open
View article: 3D Printing Methods for Bioceramic-Based Scaffold Fabrication for Craniomaxillofacial Bone Tissue Engineering
3D Printing Methods for Bioceramic-Based Scaffold Fabrication for Craniomaxillofacial Bone Tissue Engineering Open
3D Printing (3DP) technology has revolutionized the field of the use of bioceramics for maxillofacial and periodontal applications, offering unprecedented control over the shape, size, and structure of bioceramic implants. In addition, bio…
View article: Effects of a stabilized stannous fluoride dentifrice on clinical, immunomodulatory, and microbial outcomes in a human experimental gingivitis model
Effects of a stabilized stannous fluoride dentifrice on clinical, immunomodulatory, and microbial outcomes in a human experimental gingivitis model Open
Background Stannous fluoride dentifrice is well established for its beneficial clinical effects. In this study, we evaluated the effects of stannous fluoride on inflammation and oral microbiome. Methods In this randomized, parallel‐arm, do…
View article: Dental Extractions Before Radiation Therapy and the Risk of Osteoradionecrosis in Patients With Head and Neck Cancer
Dental Extractions Before Radiation Therapy and the Risk of Osteoradionecrosis in Patients With Head and Neck Cancer Open
Importance Patients with head and neck cancer undergo extraction of teeth with poor prognoses to minimize post-radiation therapy (RT) extractions, which are known to cause osteoradionecrosis (ORN). However, many patients are required to st…
View article: The Role of Bacterial, Dentinal, Salivary, and Neutrophil Degradative Activity in Caries Pathogenesis
The Role of Bacterial, Dentinal, Salivary, and Neutrophil Degradative Activity in Caries Pathogenesis Open
Until recently, it was widely accepted that bacteria participate in caries pathogenesis mainly through carbohydrate fermentation and acid production, which promote the dissolution of tooth components. Neutrophils, on the other hand, were c…