Michael Gulledge
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View article: Spontaneous oxycodone withdrawal disrupts sleep, diurnal, and electrophysiological dynamics in rats
Spontaneous oxycodone withdrawal disrupts sleep, diurnal, and electrophysiological dynamics in rats Open
Opioid dependence is defined by an aversive withdrawal syndrome upon drug cessation that can motivate continued drug-taking, development of opioid use disorder, and precipitate relapse. An understudied but common opioid withdrawal symptom …
View article: A sleep-inducing gene, <i>nemuri</i> , links sleep and immune function in <i>Drosophila</i>
A sleep-inducing gene, <i>nemuri</i> , links sleep and immune function in <i>Drosophila</i> Open
Sleep-promoting molecule found in flies Even the humble fruit fly needs sleep. Toda et al. screened ∼12,000 fruit fly lines and identified a single sleep-promoting molecule encoded by a gene they named nemuri (Japanese for “sleep,” abbrevi…