Michael J. Mueller
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View article: Enhancing mindfulness and compassion through an ayahuasca-inspired formulation containing N,N-DMT and harmine: A randomized controlled trial in healthy subjects
Enhancing mindfulness and compassion through an ayahuasca-inspired formulation containing N,N-DMT and harmine: A randomized controlled trial in healthy subjects Open
Background: Mindfulness and compassion are therapeutically relevant and can be increased through different forms of meditation practices. However, meditation practice needs time and commitment. These resources are often limited in patients…
View article: Ayahuasca-inspired DMT/HAR formulation reduces brain differentiation between self and other faces
Ayahuasca-inspired DMT/HAR formulation reduces brain differentiation between self and other faces Open
View article: Ayahuasca-Inspired DMT/HAR Formulation Reduces Brain Differentiation Between Self and Other Faces
Ayahuasca-Inspired DMT/HAR Formulation Reduces Brain Differentiation Between Self and Other Faces Open
Background Psychedelics are known to profoundly alter perception and self-referential processing, yet their specific effects on face recognition—a key aspect of social cognition—remain underexplored. Objective This study investigates the e…
View article: Use of computed tomography to identify muscle quality subgroups, spatial mapping, and preliminary relationships to function in those with diabetic peripheral neuropathy
Use of computed tomography to identify muscle quality subgroups, spatial mapping, and preliminary relationships to function in those with diabetic peripheral neuropathy Open
View article: Potential therapeutic effects of an ayahuasca-inspired N,N-DMT and harmine formulation: a controlled trial in healthy subjects
Potential therapeutic effects of an ayahuasca-inspired N,N-DMT and harmine formulation: a controlled trial in healthy subjects Open
Background There is growing scientific evidence for the therapeutic benefits of the Amazonian plant-based psychedelic “ayahuasca” for neuropsychiatric disorders such as depression and anxiety. However, there are certain challenges when inc…
View article: Overcoming the clinical challenges of traditional ayahuasca: a first-in-human trial exploring novel routes of administration of N,N-Dimethyltryptamine and harmine
Overcoming the clinical challenges of traditional ayahuasca: a first-in-human trial exploring novel routes of administration of N,N-Dimethyltryptamine and harmine Open
Recently, the Amazonian plant medicine “ayahuasca”—containing the psychedelic compound N,N-dimethyltryptamine (DMT) and numerous β-carboline alkaloids, such as harmine—has been suggested to exhibit beneficial effects in patients with affec…
View article: Use of Computed Tomography to Identify Muscle Quality Subgroups, Spatial Mapping, and Preliminary Relationships to Function in Those with Diabetic Peripheral Neuropathy
Use of Computed Tomography to Identify Muscle Quality Subgroups, Spatial Mapping, and Preliminary Relationships to Function in Those with Diabetic Peripheral Neuropathy Open
View article: Quantative MRI predicts tendon mechanical behavior, collagen composition, and organization
Quantative MRI predicts tendon mechanical behavior, collagen composition, and organization Open
Quantitative magnetic resonance imaging (qMRI) measures have provided insights into the composition, quality, and structure‐function of musculoskeletal tissues. Low signal‐to‐noise ratio has limited application to tendon. Advances in scann…
View article: Computed Tomography and Magnetic Resonance Correlation and Agreement for Foot Muscle and Adipose Tissue Measurements
Computed Tomography and Magnetic Resonance Correlation and Agreement for Foot Muscle and Adipose Tissue Measurements Open
Background Volumetric measures of intrinsic foot muscle and intermuscular adipose tissue (IMAT) infiltration are important in understanding foot injury and disease. We questioned whether measures of muscle and fat derived from computed tom…
View article: Body mass index and maximum available midfoot motion are associated with midfoot angle at peak heel rise in people with type 2 diabetes mellitus and peripheral neuropathy
Body mass index and maximum available midfoot motion are associated with midfoot angle at peak heel rise in people with type 2 diabetes mellitus and peripheral neuropathy Open
View article: Pelvic Floor Mobility Measured by Transperineal Ultrasound Imaging in Women With and Without Urgency and Frequency Predominant Lower Urinary Tract Symptoms
Pelvic Floor Mobility Measured by Transperineal Ultrasound Imaging in Women With and Without Urgency and Frequency Predominant Lower Urinary Tract Symptoms Open
Background: Women with urgency/frequency predominant lower urinary tract symptoms (UF-LUTS) may have elevated pelvic floor muscle (PFM) position at rest and limited mobility with PFM contraction and bearing down, but this has not been quan…
View article: A limited number of slices yields comparable results to all slices in foot intrinsic muscle deterioration ratio on computed tomography and magnetic resonance imaging
A limited number of slices yields comparable results to all slices in foot intrinsic muscle deterioration ratio on computed tomography and magnetic resonance imaging Open
View article: Deteriorated regional calf microcirculation measured by contrast-free MRI in patients with diabetes mellitus and relation with physical activity
Deteriorated regional calf microcirculation measured by contrast-free MRI in patients with diabetes mellitus and relation with physical activity Open
Objective: To evaluate regional calf muscle microcirculation in people with diabetes mellitus (DM) with and without foot ulcers, compared to healthy control people without DM, using contrast-free magnetic resonance imaging methods. Methods…
View article: Hip and Pelvic Floor Muscle Strength in Women With and Without Urgency and Frequency-Predominant Lower Urinary Tract Symptoms
Hip and Pelvic Floor Muscle Strength in Women With and Without Urgency and Frequency-Predominant Lower Urinary Tract Symptoms Open
Background: Urgency and frequency are common lower urinary tract symptoms (UF-LUTS) in women. There is limited evidence to guide physical therapist-led treatment. Objectives: To compare hip and pelvic floor muscle strength between women wi…
View article: Association of toe-extension movement pattern magnitude and variability during three functional tasks with diabetic foot complications
Association of toe-extension movement pattern magnitude and variability during three functional tasks with diabetic foot complications Open
View article: Heel Rise and Non–Weight-Bearing Ankle Plantar Flexion Tasks to Assess Foot and Ankle Function in People With Diabetes Mellitus and Peripheral Neuropathy
Heel Rise and Non–Weight-Bearing Ankle Plantar Flexion Tasks to Assess Foot and Ankle Function in People With Diabetes Mellitus and Peripheral Neuropathy Open
Objective The objective of this study was to examine the effects of diabetes mellitus and peripheral neuropathy (DMPN), limited joint mobility, and weight-bearing on foot and ankle sagittal movements and characterize the foot and ankle pos…
View article: Should weight-bearing activity be reduced during healing of plantar diabetic foot ulcers, even when using appropriate offloading devices?
Should weight-bearing activity be reduced during healing of plantar diabetic foot ulcers, even when using appropriate offloading devices? Open
View article: One‐year outcomes following physical therapist‐led intervention for chronic hip‐related groin pain: Ancillary analysis of a pilot multicenter randomized clinical trial
One‐year outcomes following physical therapist‐led intervention for chronic hip‐related groin pain: Ancillary analysis of a pilot multicenter randomized clinical trial Open
Evidence related to physical therapist‐led intervention for patients with chronic hip‐related groin pain (HRGP) is limited. The purpose was to assess sustainability of treatment effects for people with HRGP undergoing two physical therapis…
View article: Static Ankle Dorsiflexion and Hip and Pelvis Kinematics During Forward Step-Down in Patients With Hip-Related Groin Pain
Static Ankle Dorsiflexion and Hip and Pelvis Kinematics During Forward Step-Down in Patients With Hip-Related Groin Pain Open
Context : The authors hypothesized that in people with hip-related groin pain, less static ankle dorsiflexion could lead to compensatory hip adduction and contralateral pelvic drop during step-down. Ankle dorsiflexion may be a modifiable f…
View article: Midfoot and ankle motion during heel rise and gait are related in people with diabetes and peripheral neuropathy
Midfoot and ankle motion during heel rise and gait are related in people with diabetes and peripheral neuropathy Open
View article: Multi-System Factors Associated with Metatarsophalangeal Joint Deformity in Individuals with Type 2 Diabetes
Multi-System Factors Associated with Metatarsophalangeal Joint Deformity in Individuals with Type 2 Diabetes Open
The underlying factors contributing to metatarsophalangeal joint deformity, a known precursor to skin breakdown in individuals with diabetes mellitus (DM), is likely to involve multiple body systems. The purpose of this cross-sectional stu…
View article: Relationships within and between lower and upper extremity dysfunction in people with diabetes
Relationships within and between lower and upper extremity dysfunction in people with diabetes Open
View article: Movement pattern training compared with standard strengthening and flexibility among patients with hip-related groin pain: results of a pilot multicentre randomised clinical trial
Movement pattern training compared with standard strengthening and flexibility among patients with hip-related groin pain: results of a pilot multicentre randomised clinical trial Open
Study design Pilot, multicentre randomised clinical trial (RCT). Objectives Assess viability of performing a definitive RCT and compare preliminary effects of movement pattern training (MoveTrain) and strengthening/flexibility (Standard) t…
View article: Hip Kinematics During Single-Leg Tasks in People With and Without Hip-Related Groin Pain and the Association Among Kinematics, Hip Muscle Strength, and Bony Morphology
Hip Kinematics During Single-Leg Tasks in People With and Without Hip-Related Groin Pain and the Association Among Kinematics, Hip Muscle Strength, and Bony Morphology Open
Objective To compare 3-D hip kinematics during the single-leg squat and step-down in patients with hip-related groin pain to those in asymptomatic participants, and to assess relationships among hip kinematics, muscle strength, and bony mo…
View article: Mobility advice to help prevent re‐ulceration in diabetes
Mobility advice to help prevent re‐ulceration in diabetes Open
Clinicians and patients face a dilemma in understanding how best to resume walking after a healed diabetic neuropathic ulcer. The objectives of this brief review are to: provide context for the patient's health and mobility status; propose…
View article: 英文原稿の紹介 糖尿病および末梢神経障害を併存する患者に対する荷重位運動と免荷運動の比較 : ランダム化比較試験
英文原稿の紹介 糖尿病および末梢神経障害を併存する患者に対する荷重位運動と免荷運動の比較 : ランダム化比較試験 Open
View article: Diffusion Tensor Imaging of the Calf Muscles in Subjects With and Without Diabetes Mellitus
Diffusion Tensor Imaging of the Calf Muscles in Subjects With and Without Diabetes Mellitus Open
Background Diffusion tensor imaging (DTI) has been used to characterize calf skeletal muscle architecture. Purpose To assess the diffusional properties of the calf muscles of subjects with and without diabetes, at rest and during isometric…
View article: Three dimensional kinematics of visually classified lower extremity movement patterns during a single leg squat among people with chronic hip joint pain
Three dimensional kinematics of visually classified lower extremity movement patterns during a single leg squat among people with chronic hip joint pain Open
Describe the proportional occurrence of visually determined, lower extremity movement patterns (dynamic knee valgus [DKVal], neutral [NEU], dynamic knee varus [DKVar]) during a single leg squat (SLSquat) among patients with chronic hip joi…
View article: Effect of a Shoulder Movement Intervention on Joint Mobility, Pain, and Disability in People With Diabetes: A Randomized Controlled Trial
Effect of a Shoulder Movement Intervention on Joint Mobility, Pain, and Disability in People With Diabetes: A Randomized Controlled Trial Open
Background People with diabetes are at high risk for shoulder pain, limited joint mobility, and adhesive capsulitis. Objective The objective of this study was to evaluate the effects of a shoulder movement intervention (ShoMo) compared to …
View article: Reduced Hip Adduction Is Associated With Improved Function After Movement-Pattern Training in Young People With Chronic Hip Joint Pain
Reduced Hip Adduction Is Associated With Improved Function After Movement-Pattern Training in Young People With Chronic Hip Joint Pain Open
Study Design Ancillary analysis, time-controlled randomized clinical trial. Background Movement-pattern training (MPT) has been shown to improve function among patients with chronic hip joint pain (CHJP). Objective To determine the associa…