Michael Jaeger
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View article: Learned Regularization for Quantitative Pulse-Echo Speed-of-Sound Imaging
Learned Regularization for Quantitative Pulse-Echo Speed-of-Sound Imaging Open
Computed ultrasound tomography in echo mode generates maps of tissue speed of sound (SoS) from the shift of echoes when detected under varying steering angles. It solves a linearized inverse problem that requires regularization to compleme…
View article: Pulse-echo ultrasound attenuation tomography
Pulse-echo ultrasound attenuation tomography Open
Objective. We present the first fully two-dimensional attenuation imaging technique developed for pulse-echo ultrasound systems. Unlike state-of-the-art techniques, which use line-by-line acquisitions, our method uses steered emissions to …
View article: Pulse-echo ultrasound attenuation tomography
Pulse-echo ultrasound attenuation tomography Open
We present the first fully two-dimensional attenuation imaging technique developed for pulse-echo ultrasound systems. Unlike state-of-the-art techniques, which use line-by-line acquisitions, our method uses steered emissions to constrain a…
View article: Windowed Radon Transform for Robust Speed-of-Sound Imaging With Pulse-Echo Ultrasound
Windowed Radon Transform for Robust Speed-of-Sound Imaging With Pulse-Echo Ultrasound Open
In recent years, methods estimating the spatial distribution of tissue speed of sound with pulse-echo ultrasound are gaining considerable traction. They can address limitations of B-mode imaging, for instance in diagnosing fatty liver dise…
View article: First-in-human diagnostic study of hepatic steatosis with computed ultrasound tomography in echo mode
First-in-human diagnostic study of hepatic steatosis with computed ultrasound tomography in echo mode Open
Background Non-alcoholic fatty liver disease is rapidly emerging as the leading global cause of chronic liver disease. Efficient disease management requires low-cost, non-invasive techniques for diagnosing hepatic steatosis accurately. Her…
View article: Excluding Echo Shift Noise in Real-Time Pulse-Echo Speed-of-Sound Imaging
Excluding Echo Shift Noise in Real-Time Pulse-Echo Speed-of-Sound Imaging Open
Computed ultrasound tomography in echo mode (CUTE) allows real-time imaging of the tissue speed of sound (SoS) using handheld ultrasound. The SoS is retrieved by inverting a forward model that relates the spatial distribution of the tissue…
View article: Efficacy and Clinical Outcomes of Minimally Invasive Direct Thoracic Interbody Fusion: A Retrospective Analysis
Efficacy and Clinical Outcomes of Minimally Invasive Direct Thoracic Interbody Fusion: A Retrospective Analysis Open
This study provides further evidence for the safety and efficacy of the MIS-DTIF approach for surgical management of symptomatically refractory patients with thoracic disc herniation or stenosis owing to degenerative disc disease or compre…
View article: Towards Attenuation Imaging with Computed Ultrasound Tomography in Echo Mode (CUTE)
Towards Attenuation Imaging with Computed Ultrasound Tomography in Echo Mode (CUTE) Open
This work presents a novel attenuation imaging technique for pulse-echo ultrasound systems. In contrast to state-of-the-art techniques, we formulate the reconstruction in two dimensions relying on tissue insonifications with different stee…
View article: Towards Attenuation Imaging with Computed Ultrasound Tomography in Echo Mode (CUTE)
Towards Attenuation Imaging with Computed Ultrasound Tomography in Echo Mode (CUTE) Open
This work presents a novel attenuation imaging technique for pulse-echo ultrasound systems. In contrast to state-of-the-art techniques, we formulate the reconstruction in two dimensions relying on tissue insonifications with different stee…
View article: Pulse-echo speed-of-sound imaging using convex probes
Pulse-echo speed-of-sound imaging using convex probes Open
Computed ultrasound tomography in echo mode (CUTE) is a new ultrasound (US)-based medical imaging modality with promise for diagnosing various types of disease based on the tissue’s speed of sound (SoS). It is developed for conventional pu…
View article: Toward speed-of-sound anisotropy quantification in muscle with pulse-echo ultrasound
Toward speed-of-sound anisotropy quantification in muscle with pulse-echo ultrasound Open
The velocity of ultrasound longitudinal waves (speed of sound) is emerging as a valuable biomarker for a wide range of diseases, including musculoskeletal disorders. Muscles are fiber-rich tissues that exhibit anisotropic behavior, meaning…
View article: First-in-human diagnostic study of hepatic steatosis with computed ultrasound tomography in echo mode (CUTE)
First-in-human diagnostic study of hepatic steatosis with computed ultrasound tomography in echo mode (CUTE) Open
Non-alcoholic fatty liver disease is rapidly emerging as the leading global cause of chronic liver disease. Efficient disease management requires low-cost, noninvasive techniques for diagnosing hepatic steatosis accurately. Here we propose…
View article: Toward Speed-of-Sound Anisotropy Quantification in Muscle With Pulse-Echo Ultrasound
Toward Speed-of-Sound Anisotropy Quantification in Muscle With Pulse-Echo Ultrasound Open
The velocity of ultrasound longitudinal waves (speed of sound) is emerging as a valuable biomarker for a wide range of diseases, including musculoskeletal disorders. Muscles are fiber-rich tissues that exhibit anisotropic behavior, meaning…
View article: Machine learning enabled multiple illumination quantitative optoacoustic oximetry imaging in humans
Machine learning enabled multiple illumination quantitative optoacoustic oximetry imaging in humans Open
Optoacoustic (OA) imaging is a promising modality for quantifying blood oxygen saturation (sO 2 ) in various biomedical applications – in diagnosis, monitoring of organ function, or even tumor treatment planning. We present an accurate and…
View article: Machine learning enabled multiple illumination quantitative optoacoustic oximetry imaging in humans - Data
Machine learning enabled multiple illumination quantitative optoacoustic oximetry imaging in humans - Data Open
Recorded raw data and result data for the paper "Machine learning enabled multiple illumination quantitative optoacoustic oximetry imaging in humans"
View article: Machine learning enabled multiple illumination quantitative optoacoustic oximetry imaging in humans - Data
Machine learning enabled multiple illumination quantitative optoacoustic oximetry imaging in humans - Data Open
Recorded raw data and result data for the paper "Machine learning enabled multiple illumination quantitative optoacoustic oximetry imaging in humans"
View article: Machine learning enabled multiple illumination quantitative optoacoustic imaging of blood oxygenation in humans
Machine learning enabled multiple illumination quantitative optoacoustic imaging of blood oxygenation in humans Open
Optoacoustic (OA) imaging is a promising modality for quantifying blood oxygen saturation (sO$_2$) in various biomedical applications - in diagnosis, monitoring of organ function or even tumor treatment planning. We present an accurate and…
View article: Toward Real-Time Giga-Voxel Optoacoustic/Photoacoustic Microscopy: GPU-Accelerated Fourier Reconstruction with Quasi-3D Implementation
Toward Real-Time Giga-Voxel Optoacoustic/Photoacoustic Microscopy: GPU-Accelerated Fourier Reconstruction with Quasi-3D Implementation Open
We propose a GPU-accelerated implementation of frequency-domain synthetic aperture focusing technique (SAFT) employing truncated regularized inverse k-space interpolation. Our implementation achieves sub-1s reconstruction time for data siz…
View article: Toward speed-of-sound anisotropy quantification in muscle with pulse-echo ultrasound
Toward speed-of-sound anisotropy quantification in muscle with pulse-echo ultrasound Open
The velocity of ultrasound longitudinal waves (speed of sound) is emerging as a valuable biomarker for a wide range of diseases, including musculoskeletal disorders. Muscles are fiber-rich tissues that exhibit anisotropic behavior, meaning…
View article: Backscattering polarimetric imaging of the human brain to determine the orientation and degree of alignment of nerve fiber bundles
Backscattering polarimetric imaging of the human brain to determine the orientation and degree of alignment of nerve fiber bundles Open
The nerve fiber bundles constitutive of the white matter in the brain are organized in such a way that they exhibit a certain degree of structural anisotropy and birefringence. The birefringence exhibited by such aligned fibrous tissue is …
View article: Polarimetric imaging of the human brain to determine the orientation and\n degree of alignment of nerve fiber bundles
Polarimetric imaging of the human brain to determine the orientation and\n degree of alignment of nerve fiber bundles Open
More children and adults under the age of 40 die of brain tumor than from any\nother cancer. Brain surgery constitutes the first and decisive step for the\ntreatment of such tumors. It is extremely crucial to achieve complete tumor\nresect…
View article: Polarimetric imaging of the human brain to determine the orientation and degree of alignment of nerve fiber bundles
Polarimetric imaging of the human brain to determine the orientation and degree of alignment of nerve fiber bundles Open
More children and adults under the age of 40 die of brain tumor than from any other cancer. Brain surgery constitutes the first and decisive step for the treatment of such tumors. It is extremely crucial to achieve complete tumor resection…
View article: Bayesian Approach for a Robust Speed-of-Sound Reconstruction Using Pulse-Echo Ultrasound
Bayesian Approach for a Robust Speed-of-Sound Reconstruction Using Pulse-Echo Ultrasound Open
Computed ultrasound tomography in echo mode (CUTE) is a promising ultrasound (US) based multi-modal technique that allows to image the spatial distribution of speed of sound (SoS) inside tissue using hand-held pulse-echo US. It is based on…
View article: Improved forward model for quantitative pulse-echo speed-of-sound imaging
Improved forward model for quantitative pulse-echo speed-of-sound imaging Open
Computed ultrasound tomography in echo mode (CUTE) allows determining the spatial distribution of speed-of-sound (SoS) inside tissue using handheld pulse-echo ultrasound (US). This technique is based on measuring the changing phase of beam…
View article: Polarimetric imaging in backscattering for the structural characterization of strongly scattering birefringent fibrous media
Polarimetric imaging in backscattering for the structural characterization of strongly scattering birefringent fibrous media Open
Interpreting the polarimetric data from fiber-like macromolecules constitutive of tissue can be difficult due to strong scattering. In this study, we probed the superficial layers of fibrous tissue models (membranes consisting of nanofiber…
View article: Reliability assessment for blood oxygen saturation levels measured with optoacoustic imaging
Reliability assessment for blood oxygen saturation levels measured with optoacoustic imaging Open
The metric is independent of the methods used for the OA data acquisition, image reconstruction, and spectral correction, thus it can be readily combined with existing approaches, in order to monitor the accuracy of quantitative OA imaging.
View article: Quantitative comparison of frequency-domain and delay-and-sum optoacoustic image reconstruction including the effect of coherence factor weighting
Quantitative comparison of frequency-domain and delay-and-sum optoacoustic image reconstruction including the effect of coherence factor weighting Open
Image reconstruction in optoacoustic imaging is often based on a delay-and-sum (DAS) or a frequency domain (FD) algorithm. In this study, we performed a comprehensive comparison of these two algorithms together with coherence factor (CF) w…
View article: Receive Beam-Steering and Clutter Reduction for Imaging the Speed-of-Sound Inside the Carotid Artery
Receive Beam-Steering and Clutter Reduction for Imaging the Speed-of-Sound Inside the Carotid Artery Open
Handheld imaging of the tissue’s speed-of-sound (SoS) is a promising multimodal addition to diagnostic ultrasonography for the examination of tissue composition. Computed ultrasound tomography in echo mode (CUTE) probes the spatial distrib…
View article: Spectral correction for handheld optoacoustic imaging by means of near‐infrared optical tomography in reflection mode
Spectral correction for handheld optoacoustic imaging by means of near‐infrared optical tomography in reflection mode Open
In vivo imaging of tissue/vasculature oxygen saturation levels is of prime interest in many clinical applications. To this end, the feasibility of combining two distinct and complementary imaging modalities is investigated: optoacoustics (…