Michaël Joubert
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View article: Artificial intelligence-driven clinical decision support systems to assist healthcare professionals and people with diabetes in Europe at the point of care: a Delphi-based consensus roadmap
Artificial intelligence-driven clinical decision support systems to assist healthcare professionals and people with diabetes in Europe at the point of care: a Delphi-based consensus roadmap Open
The use of artificial intelligence (AI) to improve the diagnosis, assessment and treatment of people with diabetes has the potential to drive a paradigm shift in diabetes care, both minimising treatment inertia and optimising clinical outc…
View article: Hypoglycemia incidence and behavioural adjustments during free‐living unstructured physical activity in adults with type 1 diabetes using <scp>AID</scp> systems: Results from the <scp>RAPPID</scp> study
Hypoglycemia incidence and behavioural adjustments during free‐living unstructured physical activity in adults with type 1 diabetes using <span>AID</span> systems: Results from the <span>RAPPID</span> study Open
Aims To assess the frequency and management of hypoglycaemia during unstructured physical activity (PA) in adults with type 1 diabetes (T1D) using automated insulin delivery (AID) systems in real‐life settings. Materials and Methods RAPPID…
View article: Nationwide Trends in Type 1 and Type 2 Diabetes in France (2010–2019): A Population-Based Study Using a Machine Learning Classification Algorithm
Nationwide Trends in Type 1 and Type 2 Diabetes in France (2010–2019): A Population-Based Study Using a Machine Learning Classification Algorithm Open
This national study provides updated insights into diabetes in France and highlights the need to improve access to specialised care and reinforce long-term surveillance strategies.
View article: Sacubitril/Valsartan-Induced Hypoglycemia After Gastric Bypass: A Case Report with Documented Endogenous Hyperinsulinemia
Sacubitril/Valsartan-Induced Hypoglycemia After Gastric Bypass: A Case Report with Documented Endogenous Hyperinsulinemia Open
Post-bariatric hypoglycemia (PBH) is a frequent yet complex complication following Roux-en-Y gastric bypass, typically related to exaggerated insulin responses after rapid glucose absorption. Identifying alternative or contributing mechani…
View article: Performance of an Automated Insulin Delivery System in People Living With Type 2 Diabetes and Insulin Resistance: First Real-World Evidence in 26 427 Users
Performance of an Automated Insulin Delivery System in People Living With Type 2 Diabetes and Insulin Resistance: First Real-World Evidence in 26 427 Users Open
Background: Type 2 diabetes (T2D) is a phenotypically heterogeneous disease. The use of insulin is required in a significant portion of people with T2D, despite recent developments in antidiabetic medications. This study analyzes glycemic …
View article: First validity testing of GluciQuizz, a French self-questionnaire evaluating carb-counting for patients with type 1 diabetes
First validity testing of GluciQuizz, a French self-questionnaire evaluating carb-counting for patients with type 1 diabetes Open
Objective Carbohydrate intake remains one of the most influential factors affecting post-meal glucose levels in type 1 diabetes (T1D). To individualize and optimize patient education on carbohydrate counting, it is essential to assess thei…
View article: Expert Clinical Interpretation of Continuous Glucose Monitor Reports From Individuals Without Diabetes
Expert Clinical Interpretation of Continuous Glucose Monitor Reports From Individuals Without Diabetes Open
Background: Clinical interpretation of continuous glucose monitoring (CGM) data for people without diabetes has not been well established. This study aimed to investigate concordance among CGM experts in recommending clinical follow-up for…
View article: Evaluating Digital Health Solutions in Diabetes and the Role of Patient-Reported Outcomes: Targeted Literature Review
Evaluating Digital Health Solutions in Diabetes and the Role of Patient-Reported Outcomes: Targeted Literature Review Open
Background Digital health solutions (DHS) are technologies with the potential to improve patient outcomes as well as change the way care is delivered. The value of DHS for people with diabetes is not well understood, nor is it clear how to…
View article: Do continuous glucose monitoring (CGM) metrics predict macrovascular and microvascular complications in diabetes? The FACULTY protocol of a retrospective real-world cohort study
Do continuous glucose monitoring (CGM) metrics predict macrovascular and microvascular complications in diabetes? The FACULTY protocol of a retrospective real-world cohort study Open
Introduction Glycated haemoglobin (HbA1c) is currently the gold standard for assessing glycaemic control in diabetes, given the established relationship with microvascular and macrovascular complications in this condition. However, HbA1c i…
View article: Impact of teleconsultation follow-up to control low-density-lipoprotein cholesterol at one year after acute coronary syndrome: the teleobjectif prospective cohort study
Impact of teleconsultation follow-up to control low-density-lipoprotein cholesterol at one year after acute coronary syndrome: the teleobjectif prospective cohort study Open
Context High level of low-density lipoprotein cholesterol (LDL-c) is one of the most important causal and independent risk factor for recurrent atheromatous cardiovascular events. Despite the availability of several treatments that can red…
View article: Plasma Renin: A Useful Marker for Mineralocorticoid Adjustment in Patients With Primary Adrenal Insufficiency
Plasma Renin: A Useful Marker for Mineralocorticoid Adjustment in Patients With Primary Adrenal Insufficiency Open
Context Renin is a marker of blood volume. There is no consensus on the validity of plasma renin measurement for adjusting mineralocorticoid (MC) substitution in patients with primary adrenal insufficiency (PAI). Objective This work aimed …
View article: Genetic predisposition to pheochromocytoma and paraganglioma: 21 years of experience in the field
Genetic predisposition to pheochromocytoma and paraganglioma: 21 years of experience in the field Open
Our experience confirmed previously established genotype-phenotype correlations, but also highlights atypical clinical presentations, even for the same genetic variant. These data must be taken into account for optimal patient follow-up an…
View article: Heterogeneity of glycaemic phenotypes in type 1 diabetes
Heterogeneity of glycaemic phenotypes in type 1 diabetes Open
Aims/hypothesis Our study aims to uncover glycaemic phenotype heterogeneity in type 1 diabetes. Methods In the Study of the French-speaking Society of Type 1 Diabetes (SFDT1), we characterised glycaemic heterogeneity thanks to a set of com…
View article: Empagliflozin mitigates metabolic dysfunction‐associated steatotic liver disease by reducing de novo lipogenesis in a mouse model of lipoatrophic diabetes
Empagliflozin mitigates metabolic dysfunction‐associated steatotic liver disease by reducing de novo lipogenesis in a mouse model of lipoatrophic diabetes Open
International audience
View article: Association Between Treatment Adherence and Continuous Glucose Monitoring Outcomes in People With Diabetes Using Smart Insulin Pens in a Real-World Setting
Association Between Treatment Adherence and Continuous Glucose Monitoring Outcomes in People With Diabetes Using Smart Insulin Pens in a Real-World Setting Open
OBJECTIVETo evaluate the association between insulin injection adherence, smart insulin pen engagement, and glycemic control using real-world data from 16 countries from adults self-administering basal insulin degludec and bolus insulin us…
View article: Association Between Treatment Adherence and Continuous Glucose Monitoring Outcomes in People With Diabetes Using Smart Insulin Pens in a Real-World Setting
Association Between Treatment Adherence and Continuous Glucose Monitoring Outcomes in People With Diabetes Using Smart Insulin Pens in a Real-World Setting Open
OBJECTIVE To evaluate the association of insulin injection adherence, smart insulin pen engagement, and glycemic control using real-world data from 16 countries from adults self-administering basal insulin degludec and bolus insulin with a…
View article: Association Between Treatment Adherence and Continuous Glucose Monitoring Outcomes in People With Diabetes Using Smart Insulin Pens in a Real-World Setting
Association Between Treatment Adherence and Continuous Glucose Monitoring Outcomes in People With Diabetes Using Smart Insulin Pens in a Real-World Setting Open
OBJECTIVETo evaluate the association between insulin injection adherence, smart insulin pen engagement, and glycemic control using real-world data from 16 countries from adults self-administering basal insulin degludec and bolus insulin us…
View article: Cost-utility of real-time continuous glucose monitoring versus self-monitoring of blood glucose in people with insulin-treated Type II diabetes in France
Cost-utility of real-time continuous glucose monitoring versus self-monitoring of blood glucose in people with insulin-treated Type II diabetes in France Open
Aim: Clinical trials and real-world data for Type II diabetes both show that glycated hemoglobin (HbA1c) levels and hypoglycemia occurrence can be reduced by real-time continuous glucose monitoring (rt-CGM) versus self-monitoring of blood …
View article: Cardiovascular and renal diseases in type 2 diabetes patients: 5-year cumulative incidence of the first occurred manifestation and hospitalization cost: a cohort within the French SNDS nationwide claims database
Cardiovascular and renal diseases in type 2 diabetes patients: 5-year cumulative incidence of the first occurred manifestation and hospitalization cost: a cohort within the French SNDS nationwide claims database Open
Background Myocardial infarction (MI), stroke, peripheral arterial disease (PAD), heart failure (HF) and chronic kidney disease (CKD) are common cardiovascular renal diseases (CVRD) manifestations for type 2 diabetes. The objective was to …
View article: Cardiovascular and renal diseases in type 2 diabetes patients: 5-year cumulative incidence of the first occurred manifestation and hospitalization cost: a cohort within the French SNDS nationwide claims database
Cardiovascular and renal diseases in type 2 diabetes patients: 5-year cumulative incidence of the first occurred manifestation and hospitalization cost: a cohort within the French SNDS nationwide claims database Open
Background Myocardial infarction (MI), stroke, peripheral arterial disease (PAD), heart failure (HF) and chronic kidney disease (CKD) are common cardiovascular renal disease (CVRD) manifestations for type 2 diabetes. The incidence of the f…
View article: Glucose fluctuation promotes mitochondrial dysfunctions in the cardiomyocyte cell line HL-1
Glucose fluctuation promotes mitochondrial dysfunctions in the cardiomyocyte cell line HL-1 Open
Aims Glycemic variability has been suggested as a risk factor for diabetes complications but the precise deleterious mechanisms remain poorly understood. Since mitochondria are the main source of energy in heart and cardiovascular diseases…
View article: Safety and Efficacy of Sustained Automated Insulin Delivery Compared to Sensor and Pump Therapy in Adults with Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlled Trial.
Safety and Efficacy of Sustained Automated Insulin Delivery Compared to Sensor and Pump Therapy in Adults with Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlled Trial. Open
OBJECTIVE Assess the safety and efficacy of automated insulin delivery (AID) in adults with type 1 diabetes (T1D) at high risk for hypoglycemia. RESEARCH DESIGN AND METHODS Participants: 72 adults with T1D using insulin pump with Clarke sc…
View article: Safety and Efficacy of Sustained Automated Insulin Delivery Compared to Sensor and Pump Therapy in Adults with Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlled Trial.
Safety and Efficacy of Sustained Automated Insulin Delivery Compared to Sensor and Pump Therapy in Adults with Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlled Trial. Open
OBJECTIVE Assess the safety and efficacy of automated insulin delivery (AID) in adults with type 1 diabetes (T1D) at high risk for hypoglycemia. RESEARCH DESIGN AND METHODS Participants: 72 adults with T1D using insulin pump with Clarke sc…
View article: Safety and Efficacy of Sustained Automated Insulin Delivery Compared With Sensor and Pump Therapy in Adults With Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlled Trial
Safety and Efficacy of Sustained Automated Insulin Delivery Compared With Sensor and Pump Therapy in Adults With Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlled Trial Open
OBJECTIVE Assess the safety and efficacy of automated insulin delivery (AID) in adults with type 1 diabetes (T1D) at high risk for hypoglycemia. RESEARCH DESIGN AND METHODS Participants were 72 adults with T1D who used an insulin pump with…
View article: The value of digital health solutions in diabetes: the role of patient-reported outcomes (Preprint)
The value of digital health solutions in diabetes: the role of patient-reported outcomes (Preprint) Open
BACKGROUND Digital health solutions (DHS) are technologies with the potential to improve outcomes as well as change the way care is delivered. The value of DHS for people with diabetes is not well understood, nor is it clear how to quanti…
View article: Sensor-Augmented Insulin Pump with Predictive Low-Glucose Suspend (PLGS): Determining Optimal Settings of Pump and Sensor in a Multicenter Cohort of Patients with Type 1 Diabetes
Sensor-Augmented Insulin Pump with Predictive Low-Glucose Suspend (PLGS): Determining Optimal Settings of Pump and Sensor in a Multicenter Cohort of Patients with Type 1 Diabetes Open
This study is registered in clinicaltrials.gov (NCT03047486).