Michael Kalloniatis
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View article: Visual Field Progression Rates in Glaucoma: Frontloaded Versus Clinical Standard (Nonfrontloaded) SITA-Faster
Visual Field Progression Rates in Glaucoma: Frontloaded Versus Clinical Standard (Nonfrontloaded) SITA-Faster Open
Frontloaded (two 24-2 SITA-Faster VF tests per eye per visit) tests detected more than twice the number of glaucoma progressors based on MD slopes in a cohort of patients with predominantly early glaucoma, compared with the clinical standa…
View article: ChatGPT-4 for addressing patient-centred frequently asked questions in age-related macular degeneration clinical practice
ChatGPT-4 for addressing patient-centred frequently asked questions in age-related macular degeneration clinical practice Open
Purpose Large language models have shown promise in answering questions related to medical conditions. This study evaluated the responses of ChatGPT-4 in answering patient-centred frequently asked questions (FAQs) relevant in age-related m…
View article: Predicting visual field global and local parameters from OCT measurements using explainable machine learning
Predicting visual field global and local parameters from OCT measurements using explainable machine learning Open
View article: OCT-based diagnosis of glaucoma and glaucoma stages using explainable machine learning
OCT-based diagnosis of glaucoma and glaucoma stages using explainable machine learning Open
View article: Standard automated perimetry for glaucoma and diseases of the retina and visual pathways: Current and future perspectives
Standard automated perimetry for glaucoma and diseases of the retina and visual pathways: Current and future perspectives Open
Static automated perimetry (SAP) remains a mainstay of functional assessment of the visual field in diseases of the visual pathway, such as glaucoma and age-related macular degeneration. The fundamental psychophysical task of responding to…
View article: Visual field testing in glaucoma using the Swedish Interactive Thresholding Algorithm (SITA)
Visual field testing in glaucoma using the Swedish Interactive Thresholding Algorithm (SITA) Open
The Swedish Interactive Thresholding Algorithm (SITA) is the main measurement acquisition algorithm used on the Humphrey Field Analyser, the most commonly used instrument for visual field (VF) assessment worldwide. We compare the sensitivi…
View article: Exploring the relationship between 24‐2 visual field and widefield optical coherence tomography data across healthy, glaucoma suspect and glaucoma eyes
Exploring the relationship between 24‐2 visual field and widefield optical coherence tomography data across healthy, glaucoma suspect and glaucoma eyes Open
Purpose To utilise ganglion cell‐inner plexiform layer (GCIPL) measurements acquired using widefield optical coherence tomography (OCT) scans spanning 55° × 45° to explore the link between co‐localised structural parameters and clinical vi…
View article: Retinal sensitivity changes in early/intermediate AMD: a systematic review and meta-analysis of visual field testing under mesopic and scotopic lighting
Retinal sensitivity changes in early/intermediate AMD: a systematic review and meta-analysis of visual field testing under mesopic and scotopic lighting Open
View article: The effect of macular visual field test density on central structure-function concordance in glaucoma
The effect of macular visual field test density on central structure-function concordance in glaucoma Open
There is a potential critical number (8-14) in macular visual field testing where binarized structure-function concordance is optimised, providing a framework for guiding the development of integrated macular test locations in VF testing f…
View article: Optical coherence tomography angiography in the diagnosis of ocular disease
Optical coherence tomography angiography in the diagnosis of ocular disease Open
Clinical imaging provided by optical coherence tomography (OCT) and its variant, OCT-angiography (OCT-A), has revolutionised eyecare practice. The imaging techniques allow for the identification and quantification of ocular structures, sup…
View article: Glaucoma: challenges and opportunities
Glaucoma: challenges and opportunities Open
View article: Frontloading visual field tests detect earlier mean deviation progression when applied to real‐world‐derived early‐stage glaucoma data
Frontloading visual field tests detect earlier mean deviation progression when applied to real‐world‐derived early‐stage glaucoma data Open
Purpose To examine the diagnostic accuracy of performing two (frontloaded) versus one (clinical standard) visual field (VF) test per visit for detecting the progression of early glaucoma in data derived from clinical populations. Methods A…
View article: Which glaucoma patients benefit from 10-2 visual field testing? Proposing the functional vulnerability zone framework
Which glaucoma patients benefit from 10-2 visual field testing? Proposing the functional vulnerability zone framework Open
The authors propose several clinical markers, focussing on the 24-2, which can guide clinicians on when the 10-2 may have utility in glaucoma assessment. The authors provide a pilot reference spreadsheet for clinicians to visualise the lik…
View article: Evaluating the clinical relevance and reliability of outer retinal band length on optical coherence tomography in retinal disease: a cross-sectional study
Evaluating the clinical relevance and reliability of outer retinal band length on optical coherence tomography in retinal disease: a cross-sectional study Open
Objectives Hyper-reflective outer retinal band (HORB) disruptions are reported across a range of retinal disease, yet a reliable, easily implemented assessment method and thorough evaluation of their association to retinal disease is lacki…
View article: Characterisation of the normal human ganglion cell–inner plexiform layer using widefield optical coherence tomography
Characterisation of the normal human ganglion cell–inner plexiform layer using widefield optical coherence tomography Open
Purpose To describe variations in ganglion cell–inner plexiform layer (GCIPL) thickness in a healthy cohort from widefield optical coherence tomography (OCT) scans. Methods Widefield OCT scans spanning 55° × 45° were acquired from 470 heal…
View article: Comparing a head‐mounted virtual reality perimeter and the Humphrey Field Analyzer for visual field testing in healthy and glaucoma patients
Comparing a head‐mounted virtual reality perimeter and the Humphrey Field Analyzer for visual field testing in healthy and glaucoma patients Open
Purpose To compare clinical visual field outputs in glaucoma and healthy patients returned by the Humphrey Field Analyzer (HFA) and virtual reality (Virtual Field, VF) perimetry. Methods One eye of 54 glaucoma patients and 41 healthy subje…
View article: Spatial Cluster Patterns of Retinal Sensitivity Loss in Intermediate Age-Related Macular Degeneration Features
Spatial Cluster Patterns of Retinal Sensitivity Loss in Intermediate Age-Related Macular Degeneration Features Open
Defining the spatial patterns of retinal sensitivity loss in iAMD can facilitate a targeted visual field protocol for iAMD assessment.
View article: Artificial intelligence in the diagnosis of glaucoma and neurodegenerative diseases
Artificial intelligence in the diagnosis of glaucoma and neurodegenerative diseases Open
Artificial Intelligence is a rapidly expanding field within computer science that encompasses the emulation of human intelligence by machines. Machine learning and deep learning – two primary data-driven pattern analysis approaches under t…
View article: Multiple (frontloaded) visual field tests increase identification of very slow mean deviation progression in glaucoma
Multiple (frontloaded) visual field tests increase identification of very slow mean deviation progression in glaucoma Open
View article: RVD: A Handheld Device-Based Fundus Video Dataset for Retinal Vessel Segmentation
RVD: A Handheld Device-Based Fundus Video Dataset for Retinal Vessel Segmentation Open
We introduce the first video-based retinal vessel dataset (RVD), a collection of 635 smartphone-based videos with detailed vessel annotation. All captured videos have a frame rate of 25 frames per second, with the duration…
View article: RVD: A Handheld Device-Based Fundus Video Dataset for Retinal Vessel Segmentation
RVD: A Handheld Device-Based Fundus Video Dataset for Retinal Vessel Segmentation Open
We introduce the first video-based retinal vessel dataset (RVD), a collection of 635 smartphone-based videos with detailed vessel annotation. All captured videos have a frame rate of 25 frames per second, with the duration…
View article: RVD: A Handheld Device-Based Fundus Video Dataset for Retinal Vessel Segmentation
RVD: A Handheld Device-Based Fundus Video Dataset for Retinal Vessel Segmentation Open
Retinal vessel segmentation is generally grounded in image-based datasets collected with bench-top devices. The static images naturally lose the dynamic characteristics of retina fluctuation, resulting in diminished dataset richness, and t…
View article: Effective health communication for age‐related macular degeneration: An exploratory qualitative study
Effective health communication for age‐related macular degeneration: An exploratory qualitative study Open
Purpose Age‐related macular degeneration (AMD) is a major cause of vision loss globally. Patients with AMD may not always understand or retain the information about AMD communicated by their eyecare practitioner. This study aims to explore…
View article: Derivation of human retinal cell densities using high‐density, spatially localized optical coherence tomography data from the human retina
Derivation of human retinal cell densities using high‐density, spatially localized optical coherence tomography data from the human retina Open
This study sought to identify demographic variations in retinal thickness measurements from optical coherence tomography (OCT), to enable the calculation of cell density parameters across the neural layers of the healthy human macula. From…
View article: Visualising structural and functional characteristics distinguishing between newly diagnosed high‐tension and low‐tension glaucoma patients
Visualising structural and functional characteristics distinguishing between newly diagnosed high‐tension and low‐tension glaucoma patients Open
Purpose To determine whether there are quantifiable structural or functional differences that can distinguish between high‐tension glaucoma (HTG; intraocular pressure [IOP] > 21 mm Hg) and low‐tension glaucoma (LTG; IOP ≤ 21 mm Hg) at diag…
View article: Loss of Müller cell glutamine synthetase immunoreactivity is associated with neuronal changes in late-stage retinal degeneration
Loss of Müller cell glutamine synthetase immunoreactivity is associated with neuronal changes in late-stage retinal degeneration Open
Introduction A hallmark of photoreceptor degenerations is progressive, aberrant remodeling of the surviving retinal neurons and glia following photoreceptor loss. The exact relationship between neurons and glia remodeling in this late stag…
View article: Drusen‐aware model for age‐related macular degeneration recognition
Drusen‐aware model for age‐related macular degeneration recognition Open
Introduction The purpose of this study was to build an automated age‐related macular degeneration (AMD) colour fundus photography (CFP) recognition method that incorporates confounders (other ocular diseases) and normal age‐related changes…
View article: Which glaucoma patients benefit from 10-2 visual field testing? Proposing the functional vulnerability zone framework
Which glaucoma patients benefit from 10-2 visual field testing? Proposing the functional vulnerability zone framework Open
A method for determining 10-2 deployment in glaucoma with the goal of detecting additional visual field sensitivity for the purpose of functional monitoring is proposed. To provide a pilot method for determining when to deploy the 10-2 vis…
View article: Diagnostic accuracy of OCTA and OCT for myopic choroidal neovascularisation: a systematic review and meta-analysis
Diagnostic accuracy of OCTA and OCT for myopic choroidal neovascularisation: a systematic review and meta-analysis Open
View article: High sampling resolution optical coherence tomography reveals potential concurrent reductions in ganglion cell‐inner plexiform and inner nuclear layer thickness but not in outer retinal thickness in glaucoma
High sampling resolution optical coherence tomography reveals potential concurrent reductions in ganglion cell‐inner plexiform and inner nuclear layer thickness but not in outer retinal thickness in glaucoma Open
Purpose To analyse optical coherence tomography (OCT)‐derived inner nuclear layer (INL) and outer retinal complex (ORC) measurements relative to ganglion cell‐inner plexiform layer (GCIPL) measurements in glaucoma. Methods Glaucoma partici…