Michael L. McDaniel
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View article: Non-contact rapid reader system for reflective particle tags
Non-contact rapid reader system for reflective particle tags Open
A reflective particle tag reader system includes a read head assembly having a camera, illuminators, and a rigid frame portion for supporting the camera and the illuminators. The illuminators illuminate a focal point located opposite the c…
View article: Eyes On the Ground: Toward a Portable Inspector?s Assistant.
Eyes On the Ground: Toward a Portable Inspector?s Assistant. Open
View article: Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway
Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway Open
Obesity-induced diabetes is characterized by hyperglycemia, insulin resistance, and progressive beta cell failure. In islets of mice with obesity-induced diabetes, we observe increased beta cell death and impaired autophagic flux. We hypot…
View article: Open Source Geographic Information for Safeguards Analysis.
Open Source Geographic Information for Safeguards Analysis. Open
View article: Harvesting Geospatial Safeguards Information with Open Source Tools.
Harvesting Geospatial Safeguards Information with Open Source Tools. Open
View article: Advances in the Use of Open-source Information.
Advances in the Use of Open-source Information. Open
View article: MSDC-0160+ IGF-1 maintains human β-cell phenotype.
MSDC-0160+ IGF-1 maintains human β-cell phenotype. Open
(A–B) MSDC-0160 treatment increases expression of β-cell specific genes. Human islets were cultured for 24 h in cCMRL, 8 mM glucose with or without the concentrations of MSDC-0160, IGF-1 and LiCl as indicated. Islets were harvested …
View article: Activation of cAMP/PKA/CREB engages canonical Wnt and IRS2/Akt signaling in human islets.
Activation of cAMP/PKA/CREB engages canonical Wnt and IRS2/Akt signaling in human islets. Open
(A) & (B) & (C) Human islets (150) were treated for 3 h with CMRL-1066 medium containing 10% FBS, 5 or 20 mM glucose, ± 10 µM forskolin ±5 mM LiCl as indicated. The PKA inhibitor (H-89, 10 µM) and Akt inhibitor (Akt inhibitor XII, 10 µM) w…
View article: ASXL2 Regulates Glucose, Lipid, and Skeletal Homeostasis
ASXL2 Regulates Glucose, Lipid, and Skeletal Homeostasis Open
ASXL2 is an ETP family protein that interacts with PPARγ. We find that ASXL2-/- mice are insulin resistant, lipodystrophic, and fail to respond to a high-fat diet. Consistent with genetic variation at the ASXL2 locus and human bone mineral…
View article: CCDC 1418217: Experimental Crystal Structure Determination
CCDC 1418217: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1418216: Experimental Crystal Structure Determination
CCDC 1418216: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1418218: Experimental Crystal Structure Determination
CCDC 1418218: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1418215: Experimental Crystal Structure Determination
CCDC 1418215: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1418219: Experimental Crystal Structure Determination
CCDC 1418219: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …