Michael Metze
YOU?
Author Swipe
View article: Long-Term Follow-Up of Professional Soccer Players: The Analyses of Left and Right Heart Morphology and Function by Conventional, Three-Dimensional, and Deformation Analyses
Long-Term Follow-Up of Professional Soccer Players: The Analyses of Left and Right Heart Morphology and Function by Conventional, Three-Dimensional, and Deformation Analyses Open
Background: Transthoracic echocardiography (TTE) is the primary imaging modality to assess cardiac morphology and function. In athletes, distinguishing physiological adaptations from pathological changes is essential. This study aimed to e…
Effects of Protamine Reversal on Coagulation Parameters After High-Dose Heparin Administration in Percutaneous Hepatic Chemosaturation Intervention Open
Background: Intravenous protamine administration for heparin reversal after percutaneous hepatic chemosaturation intervention is generally recommended, but its effectiveness on coagulation parameters remains unclear. Methods: In a single-c…
View article: The Effect of Upright Posture on Left Atrial Strain in Competitive Athletes
The Effect of Upright Posture on Left Atrial Strain in Competitive Athletes Open
Background: Left atrial strain (LAS) assessment by speckle tracking echocardiography (STE) has been shown to be a remarkable means of quantifying LA function as an early marker of LV pathology. As exercise testing is also performed on a tr…
ST-segment elevation myocardial infarction with refractory cardiogenic shock due to coronary spasm: a case report Open
Background Acute coronary syndrome (ACS) is primarily due to obstructive coronary artery disease (CAD). Nevertheless, in 1–14% of cases, ACS is present without evidence of obstructive CAD. Coronary artery spasm is an uncommon cause of ACS.…
View article: Epicardial adipose tissue defined by initial polytrauma CT of mechanically ventilated trauma patients: retrospective single-center cohort study to predict short-term outcomes
Epicardial adipose tissue defined by initial polytrauma CT of mechanically ventilated trauma patients: retrospective single-center cohort study to predict short-term outcomes Open
Purpose Epicardial adipose tissue (EAT) detected by computed tomography (CT) is associated with morbidity and mortality in patients with COVID-19 and other critical care patient cohorts, whereas their prognostic relevance in trauma patient…
View article: Detection of direct oral anticoagulants with the diluted Russel's viper venom time
Detection of direct oral anticoagulants with the diluted Russel's viper venom time Open
Introduction The activity of direct oral anticoagulants (DOAC) is important in acute clinical situations. Recent studies have suggested a strong influence of DOAC on the diluted Russel's Viper Venom Time (dRVVT). Therefore, it may be a sui…
View article: Total Thrombus-Formation System in Patients with Peripheral Artery Disease
Total Thrombus-Formation System in Patients with Peripheral Artery Disease Open
The Total Thrombus-formation Analysis System (T-TAS) is an automated device using coated microchips to assess thrombus formation under flow conditions. Its value to monitor coagulation function in patients under antiplatelet therapy awaits…
View article: Prognostic Relevance of Global Myocardial Work Index in Patients with Moderate Aortic Valve Stenosis
Prognostic Relevance of Global Myocardial Work Index in Patients with Moderate Aortic Valve Stenosis Open
Background: A reduced global myocardial work index (GWI) ≤ 1951 mmHg% is associated with increased mortality in patients with severe aortic valve stenosis (AS). However, parameters predicting the outcome in patients with moderate AS are li…
View article: Impact of Aortic Valve Regurgitation on Doppler Echocardiographic Parameters in Patients with Severe Aortic Valve Stenosis
Impact of Aortic Valve Regurgitation on Doppler Echocardiographic Parameters in Patients with Severe Aortic Valve Stenosis Open
Background: Diagnosing severe aortic stenosis (AS) depends on flow and pressure conditions. It is suspected that concomitant aortic regurgitation (AR) has an impact on the assessment of AS severity. The aim of this study was to analyze the…
View article: Comparison of quantitative flow ratio with instantaneous wave‐free ratio and resting full‐cycle ratio during daily routine in the catheterization laboratory
Comparison of quantitative flow ratio with instantaneous wave‐free ratio and resting full‐cycle ratio during daily routine in the catheterization laboratory Open
Background Quantitative flow ratio (QFR) is a novel, software‐based method to evaluate the physiology of coronary lesions. The aim of this study was to compare QFR with the established invasive measurements of coronary blood flow using ins…
View article: First case report of the use of two stents following coronary artery obstruction during indirect mitral annuloplasty
First case report of the use of two stents following coronary artery obstruction during indirect mitral annuloplasty Open
The case of a 71‐year‐old male with end stage heart failure and severe mitral regurgitation is presented, where percutaneous indirect mitral annuloplasty was performed. During device implantation in the coronary sinus the circumflex artery…
Valid and Reproducible Quantitative Assessment of Cardiac Volumes by Echocardiography in Patients with Valvular Heart Diseases—Possible or Wishful Thinking? Open
The analysis of left ventricular function is predominantly based on left ventricular volume assessment. Especially in valvular heart diseases, the quantitative assessment of total and effective stroke volumes as well as regurgitant volumes…
The impact of upright posture on left ventricular deformation in athletes Open
Besides LV ejection fraction (LVEF), global longitudinal strain (GLS) and global myocardial work index (GWI) are increasingly important for the echocardiographic assessment of left ventricular (LV) function in athletes. Since exercise test…
Weight-adjusted dosing of tinzaparin for thromboprophylaxis in obese medical patients Open
Dosing of tinzaparin adjusted for actual bodyweight in obese patients achieved anti-Xa activity in the target range for most patients, without accumulation or overdosing. In addition, there is a significant difference in thrombin generatio…
Left ventricular hypertrophy, diastolic dysfunction and right ventricular load predict outcome in moderate aortic stenosis Open
Aims Predictors of progression of moderate aortic valve stenosis (AS) are incompletely understood. The objective of this study was to evaluate the prognostic value of left ventricular hypertrophy (LVH), diastolic dysfunction, and right ven…
View article: Comparison of quantitative flow ratio (QFR) and instantaneous wave-free ratio (iFR) or resting full-cycle ratio (RFR) during daily routine in the catheterization laboratory
Comparison of quantitative flow ratio (QFR) and instantaneous wave-free ratio (iFR) or resting full-cycle ratio (RFR) during daily routine in the catheterization laboratory Open
Background The prognosis of patients with coronary artery disease (CAD) depends strongly on the hemodynamic relevance of the stenosis. The gold standard is the invasive evaluation of the stenosis using Fractional Flow Reserve (FFR), instan…
Detection of direct oral anticoagulants with the dilute Russels viper venom time – observations in a real life setting Open
Background The detection of direct oral anticoagulants (DOACs) in emergency settings still remains challenging, especially when dedicated anti-Xa or anti-IIa tests are not readily available or the specific DOAC is unknown. The dilute Russe…
View article: Prognostic value of secondary cardiac alterations in patients with moderate aortic valve stenosis
Prognostic value of secondary cardiac alterations in patients with moderate aortic valve stenosis Open
Purpose Echocardiographic characteristics that predict the progression of moderate aortic valve stenosis (mAS) are lacking. The aim of the present study was to evaluate the prognostic value of left ventricular hypertrophy (LVH), diastolic …
Influence of direct oral anticoagulants on thrombin generation on Ceveron TGA Open
Introduction Monitoring of direct oral anticoagulants (DOACs) with calibrated anti‐Xa assay is limited by the high intra‐ and interindividual variations of the test results. Thrombin generation (TG) is a global hemostatic assay that reflec…
The influence of direct oral anticoagulants on thrombin generation on Ceveron TGA Open
Introduction: Monitoring of direct oral anticoagulants (DOACs) with calibrated anti-Xa assay is limited by the high intra- and interindividual variation of the test results. Thrombin generation (TG) is a global hemostatic assay that reflec…
Plasma levels do not predict thrombin generation in patients taking direct oral anticoagulants Open
Background The antithrombotic effect of direct oral anticoagulants (DOAC) in specific clinical scenarios is difficult to assess. Objective This study aimed to evaluate the effect of DOAC on thrombin generation (TG) in relation to their pla…
Case report: isolated pulmonary valve endocarditis in a 39-year-old patient with intravenous drug abuse Open
Background Isolated pulmonary valve endocarditis is a very rare form of right-sided infective endocarditis. Due to the anatomy, in most cases, just the tricuspid valve is involved. Diagnosis can be challenging because of non-specific sympt…