Michael N. Diringer
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View article: Caring for Coma after Severe Brain Injury: Clinical Practices and Challenges to Improve Outcomes: An Initiative by the Curing Coma Campaign
Caring for Coma after Severe Brain Injury: Clinical Practices and Challenges to Improve Outcomes: An Initiative by the Curing Coma Campaign Open
View article: Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Goals-of-Care and Family/Surrogate Decision-Maker Data
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Goals-of-Care and Family/Surrogate Decision-Maker Data Open
The list of Curing Coma Campaign Collaborators included as a file in Supplementary Information has been updated. Flora Hammond, Raimund Helbok, and Naomi Niznick have been added to the list. Several spelling errors have been corrected. A r…
View article: Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Neuroimaging
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Neuroimaging Open
The list of Curing Coma Campaign Collaborators included in the Acknowledgements section has been updated. Flora Hammond, Raimund Helbok, and Naomi Niznick have been added to the list. Several spelling errors have been corrected. A revised …
View article: Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population Open
View article: Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data Open
View article: Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Electrophysiology Working Group
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Electrophysiology Working Group Open
View article: Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Hospital Course, Confounders, and Medications
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Hospital Course, Confounders, and Medications Open
View article: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Outcomes and Endpoints
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Outcomes and Endpoints Open
The DoC outcome and endpoint CDEs are a starting point in the broader effort to standardize outcome evaluation of persons with DoC. The ultimate goal is to harmonize DoC studies and allow for more precise assessment of outcomes after sever…
View article: Contemporary management of aneurysmal subarachnoid haemorrhage. An update for the intensivist
Contemporary management of aneurysmal subarachnoid haemorrhage. An update for the intensivist Open
View article: Research considerations for prospective studies of patients with coma and disorders of consciousness
Research considerations for prospective studies of patients with coma and disorders of consciousness Open
Disorders of consciousness are neurological conditions characterized by impaired arousal and awareness of self and environment. Behavioural responses are absent or are present but fluctuate. Disorders of consciousness are commonly encounte…
View article: Common Data Element for Disorders of Consciousness: Recommendations from the Working Group on Therapeutic Interventions
Common Data Element for Disorders of Consciousness: Recommendations from the Working Group on Therapeutic Interventions Open
View article: Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Behavioral Phenotyping
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Behavioral Phenotyping Open
View article: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data Open
View article: Cognitive Motor Dissociation: Gap Analysis and Future Directions
Cognitive Motor Dissociation: Gap Analysis and Future Directions Open
View article: Computational modelling in disorders of consciousness: Closing the gap towards personalised models for restoring consciousness
Computational modelling in disorders of consciousness: Closing the gap towards personalised models for restoring consciousness Open
Disorders of consciousness are complex conditions characterised by persistent loss of responsiveness due to brain injury. They present diagnostic challenges and limited options for treatment, and highlight the urgent need for a more thorou…
View article: Perceived Utility of Intracranial Pressure Monitoring in Traumatic Brain Injury: A Seattle International Brain Injury Consensus Conference Consensus-Based Analysis and Recommendations
Perceived Utility of Intracranial Pressure Monitoring in Traumatic Brain Injury: A Seattle International Brain Injury Consensus Conference Consensus-Based Analysis and Recommendations Open
BACKGROUND: Intracranial pressure (ICP) monitoring is widely practiced, but the indications are incompletely developed, and guidelines are poorly followed. OBJECTIVE: To study the monitoring practices of an established expert panel (the cl…
View article: Hemodynamic Management in the Prevention and Treatment of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage
Hemodynamic Management in the Prevention and Treatment of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage Open
View article: Prognostication and Goals of Care Decisions in Severe Traumatic Brain Injury: A Survey of The Seattle International Severe Traumatic Brain Injury Consensus Conference Working Group
Prognostication and Goals of Care Decisions in Severe Traumatic Brain Injury: A Survey of The Seattle International Severe Traumatic Brain Injury Consensus Conference Working Group Open
Abstract Best practice guidelines have advanced severe traumatic brain injury (TBI) care; however, there is little that currently informs goals of care decisions and processes despite their importance and frequency. Panelists from t…
View article: Computational modelling in disorders of consciousness: closing the gap towards personalised models for restoring consciousness
Computational modelling in disorders of consciousness: closing the gap towards personalised models for restoring consciousness Open
Disorders of consciousness are complex conditions characterised by persistent loss of responsiveness due to brain injury. They present diagnostic challenges and limited options for treatment, and highlight the urgent need for a more thorou…
View article: Correction: Mechanisms Underlying Disorders of Consciousness: Bridging Gaps to Move Toward an Integrated Translational Science
Correction: Mechanisms Underlying Disorders of Consciousness: Bridging Gaps to Move Toward an Integrated Translational Science Open
View article: Hypothermia for Patients Requiring Evacuation of Subdural Hematoma: A Multicenter Randomized Clinical Trial
Hypothermia for Patients Requiring Evacuation of Subdural Hematoma: A Multicenter Randomized Clinical Trial Open
Background Hypothermia is neuroprotective in some ischemia–reperfusion injuries. Ischemia–reperfusion injury may occur with traumatic subdural hematoma (SDH). This study aimed to determine whether early induction and maintenance of hypothe…
View article: Mechanisms Underlying Disorders of Consciousness: Bridging Gaps to Move Toward an Integrated Translational Science
Mechanisms Underlying Disorders of Consciousness: Bridging Gaps to Move Toward an Integrated Translational Science Open
View article: Proceedings of the First Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness
Proceedings of the First Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness Open
View article: Research Needs for Prognostic Modeling and Trajectory Analysis in Patients with Disorders of Consciousness
Research Needs for Prognostic Modeling and Trajectory Analysis in Patients with Disorders of Consciousness Open
View article: Therapies to Restore Consciousness in Patients with Severe Brain Injuries: A Gap Analysis and Future Directions
Therapies to Restore Consciousness in Patients with Severe Brain Injuries: A Gap Analysis and Future Directions Open
View article: Cerebrovascular Autoregulation Monitoring in the Management of Adult Severe Traumatic Brain Injury: A Delphi Consensus of Clinicians
Cerebrovascular Autoregulation Monitoring in the Management of Adult Severe Traumatic Brain Injury: A Delphi Consensus of Clinicians Open
View article: Poor Correlation Between Perihematomal MRI Hyperintensity and Brain Swelling After Intracerebral Hemorrhage
Poor Correlation Between Perihematomal MRI Hyperintensity and Brain Swelling After Intracerebral Hemorrhage Open
The perihematomal hyperintensity is commonly interpreted to represent cerebral edema following ICH, but the accuracy of this interpretation is unknown. We therefore investigated the relationship between changes in PHH and changes in hemisp…
View article: Autoregulation after ischaemic stroke
Autoregulation after ischaemic stroke Open
Absent outcome data from randomized clinical trials, management of hypertension in acute ischaemic stroke remains controversial. Data from human participants have failed to resolve the question whether cerebral blood flow (CBF) in the peri…
View article: The Curing Coma Campaign: Framing Initial Scientific Challenges—Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting
The Curing Coma Campaign: Framing Initial Scientific Challenges—Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting Open
Coma and disordered consciousness are common manifestations of acute neurological conditions and are among the most pervasive and challenging aspects of treatment in neurocritical care. Gaps exist in patient assessment, outcome prognostica…
View article: Effect of High-Dose Simvastatin on Cerebral Blood Flow and Static Autoregulation in Subarachnoid Hemorrhage
Effect of High-Dose Simvastatin on Cerebral Blood Flow and Static Autoregulation in Subarachnoid Hemorrhage Open
Statins may promote vasodilation following subarachnoid hemorrhage (SAH) and improve the response to blood pressure elevation. We sought to determine whether simvastatin increases cerebral blood flow (CBF) and alters the response to induce…