Michael Peake
YOU?
Author Swipe
View article: Impact of a recent cancer diagnosis on bleeding risk after myocardial infarction
Impact of a recent cancer diagnosis on bleeding risk after myocardial infarction Open
Background Determining the most appropriate treatment in patients with cancer with an acute myocardial infarction (MI) can be challenging. Optimal management requires an understanding of bleeding risk which may be different in this populat…
View article: Fluoropyrimidine Chemotherapy and the Risk of Death and Cardiovascular Events in Patients With Gastrointestinal Cancer
Fluoropyrimidine Chemotherapy and the Risk of Death and Cardiovascular Events in Patients With Gastrointestinal Cancer Open
The markedly improved overall survival with fluoropyrimidines in patients with gastrointestinal cancer significantly outweighs the small risk of cardiac arrhythmia and arrest. Oncologists should take this into consideration for decision ma…
View article: Identifying and exploring patient engagement interventions for people diagnosed with lung cancer: A rapid systematic review
Identifying and exploring patient engagement interventions for people diagnosed with lung cancer: A rapid systematic review Open
The protocol was registered on the International Prospective Register of Systematic Reviews (PROSPERO) (CRD42024521052) on 06/03/24.
View article: Association of pre-existing cardiovascular disease with administration of fluoropyrimidine chemotherapy in patients with gastrointestinal malignancies
Association of pre-existing cardiovascular disease with administration of fluoropyrimidine chemotherapy in patients with gastrointestinal malignancies Open
Objective Fluoropyrimidine chemotherapy is a first-line treatment for many gastrointestinal (GI) cancers, however, cardiotoxicity concerns may limit administration in patients with pre-existing cardiovascular disease (CVD). This study inve…
View article: PD05 The effects of afamelanotide on ultraviolet radiation-induced acute inflammatory and DNA repair responses in healthy human skin
PD05 The effects of afamelanotide on ultraviolet radiation-induced acute inflammatory and DNA repair responses in healthy human skin Open
Afamelanotide, a potent analogue of α-melanocyte-stimulating hormone, is known to stimulate melanogenesis by binding to the melanocortin 1 receptor. Additionally, in experimental models it has anti-inflammatory and antioxidative effects. C…
View article: 45 The impact of cancer on bleeding risk among patients beyond 1 year post-myocardial infarction: an analysis of the virtual cardio-oncology research initiative (VICORI) database
45 The impact of cancer on bleeding risk among patients beyond 1 year post-myocardial infarction: an analysis of the virtual cardio-oncology research initiative (VICORI) database Open
Introduction Cardiovascular disease and cancer are common causes of morbidity and mortality. Advancements in treatment strategies for both diseases have resulted in a growing population who live with both conditions. Myocardial infarction …
View article: A novel method for the establishment of autologous skin cell suspensions: characterisation of cellular sub-populations, epidermal stem cell content and wound response-enhancing biological properties
A novel method for the establishment of autologous skin cell suspensions: characterisation of cellular sub-populations, epidermal stem cell content and wound response-enhancing biological properties Open
Introduction: Autologous cell suspension (ACS)-based therapy represents a highly promising approach for burns and chronic wounds. However, existing technologies have not achieved the desired clinical success due to several limitations. To …
View article: A systematic review on the qualitative experiences of people living with lung cancer in rural areas
A systematic review on the qualitative experiences of people living with lung cancer in rural areas Open
Purpose To synthesize the qualitative literature exploring the experiences of people living with lung cancer in rural areas. Methods Searches were performed in MEDLINE, CINAHL, and PsycINFO. Articles were screened independently by two revi…
View article: The impact of cancer on the risk of hospitalisation for bleeding among acute coronary syndrome patients: an analysis of the Virtual Cardio-Oncology Research Initiative (VICORI) database
The impact of cancer on the risk of hospitalisation for bleeding among acute coronary syndrome patients: an analysis of the Virtual Cardio-Oncology Research Initiative (VICORI) database Open
Introduction Cardiovascular disease and cancer are common causes of morbidity and mortality. Significant advancements in treatment strategies for both disease entities have resulted in a growing population who live with both conditions. My…
View article: Impact of a Prior Cancer Diagnosis on Quality of Care and Survival Following Acute Myocardial Infarction: Retrospective Population-Based Cohort Study in England
Impact of a Prior Cancer Diagnosis on Quality of Care and Survival Following Acute Myocardial Infarction: Retrospective Population-Based Cohort Study in England Open
Background: An increasing proportion of patients with cancer experience acute myocardial infarction (AMI). We investigated differences in quality of AMI care and survival between patients with and without previous cancer diagnoses. Methods…
View article: 36 An analysis of the virtual cardio-oncology research initiative (VICORI) resource: bleeding risk among acute coronary syndrome patients with cancer
36 An analysis of the virtual cardio-oncology research initiative (VICORI) resource: bleeding risk among acute coronary syndrome patients with cancer Open
Introduction Cardiovascular disease and cancer are common causes of morbidity and mortality. Significant advancements in treatment strategies for both disease entities have resulted in a growing population who live with both conditions. My…
View article: Changing from face-to-face to virtual meetings due to the COVID-19 pandemic: protocol for a mixed-methods study exploring the impact on cancer multidisciplinary team (MDT) meetings
Changing from face-to-face to virtual meetings due to the COVID-19 pandemic: protocol for a mixed-methods study exploring the impact on cancer multidisciplinary team (MDT) meetings Open
Introduction In the UK, the National Cancer Plan (2000) requires every cancer patient’s care to be reviewed by a multidisciplinary team (MDT). Since the introduction of these guidelines, MDTs have faced escalating demands with increasing n…
View article: Acute heart failure presentation, management, and outcomes in cancer patients: a national longitudinal study
Acute heart failure presentation, management, and outcomes in cancer patients: a national longitudinal study Open
Aims Currently, little evidence exists on survival and quality of care in cancer patients presenting with acute heart failure (HF). The aim of the study is to investigate the presentation and outcomes of hospital admission with acute HF in…
View article: Improving practice in PD-L1 testing of non-small cell lung cancer in the UK: current problems and potential solutions
Improving practice in PD-L1 testing of non-small cell lung cancer in the UK: current problems and potential solutions Open
Aims Programmed cell death ligand 1 (PD-L1) expression, used universally to predict response of non-small cell lung cancer (NSCLC) to immune-modulating drugs, is a fragile biomarker due to biological heterogeneity and challenges in interpr…
View article: Promoting early diagnosis and recovering from the COVID-19 pandemic in lung cancer through public awareness campaigns: learning from patient and public insight work
Promoting early diagnosis and recovering from the COVID-19 pandemic in lung cancer through public awareness campaigns: learning from patient and public insight work Open
COVID-19 has had a devastating impact on outcomes in lung cancer leading to later stage presentation, less curative treatment and higher mortality. This has amplified the existing problem of late-stage presentation in lung cancer and is a …
View article: Association between time-to-treatment and outcomes in non-small cell lung cancer: a systematic review
Association between time-to-treatment and outcomes in non-small cell lung cancer: a systematic review Open
Background National targets for timely diagnosis and management of a potential cancer are driven in part by the perceived risk of disease progression during avoidable delays. However, it is unclear to what extent time-to-treatment impacts …
View article: Cooling-mediated protection from chemotherapy drug-induced cytotoxicity in human keratinocytes by inhibition of cellular drug uptake
Cooling-mediated protection from chemotherapy drug-induced cytotoxicity in human keratinocytes by inhibition of cellular drug uptake Open
Chemotherapy-induced alopecia (CIA) represents the most distressing side-effect for cancer patients. Scalp cooling is currently the only treatment to combat CIA, yet little is known about its cytoprotective effects in human hair follicles …
View article: Impact on survival of modelling increased surgical resection rates in patients with non-small-cell lung cancer and cardiovascular comorbidities: a VICORI study
Impact on survival of modelling increased surgical resection rates in patients with non-small-cell lung cancer and cardiovascular comorbidities: a VICORI study Open
Background The impact of cardiovascular disease (CVD) comorbidity on resection rates and survival for patients with early-stage non-small-cell lung cancer (NSCLC) is unclear. We explored if CVD comorbidity explained surgical resection rate…
View article: Sequential screening for lung cancer in a high-risk group: randomised controlled trial
Sequential screening for lung cancer in a high-risk group: randomised controlled trial Open
Background Low-dose computed tomography (LDCT) screening detects early-stage lung cancer and reduces mortality. We proposed a sequential approach targeted to a high-risk group as a potentially efficient screening strategy. Methods LungSEAR…
View article: Presentation of lung cancer in primary care
Presentation of lung cancer in primary care Open
Survival from lung cancer has seen only modest improvements in recent decades. Poor outcomes are linked to late presentation, yet early diagnosis can be challenging as lung cancer symptoms are common and non-specific. In this paper, we exa…
View article: Prophylactic Irradiation of Tracts in Patients With Malignant Pleural Mesothelioma: An Open-Label, Multicenter, Phase III Randomized Trial
Prophylactic Irradiation of Tracts in Patients With Malignant Pleural Mesothelioma: An Open-Label, Multicenter, Phase III Randomized Trial Open
PURPOSE Prophylactic irradiation to the chest wall after diagnostic or therapeutic procedures in patients with malignant pleural mesothelioma (MPM) has been a widespread practice across Europe, although the efficacy of this treatment is un…
View article: Incidence of second and higher order smoking-related primary cancers following lung cancer: a population-based cohort study
Incidence of second and higher order smoking-related primary cancers following lung cancer: a population-based cohort study Open
Background Lung cancer 5-year survival has doubled over 15 years. Although the risk of second primary cancer is recognised, quantification over time is lacking. We describe the incidence of second and higher order smoking-related primary c…
View article: Associations between general practice characteristics with use of urgent referrals for suspected cancer and endoscopies: a cross-sectional ecological study
Associations between general practice characteristics with use of urgent referrals for suspected cancer and endoscopies: a cross-sectional ecological study Open
Background Large variation in measures of diagnostic activity has been described previously between English general practices, but related predictors remain understudied. Objective To examine associations between general practice populatio…
View article: ERS statement on harmonised standards for lung cancer registration and lung cancer services in Europe
ERS statement on harmonised standards for lung cancer registration and lung cancer services in Europe Open
The European Respiratory Society (ERS) task force for harmonised standards for lung cancer registration and lung cancer services in Europe recognised the need to create a single dataset for use in pan-European data collection and a manual …