Michael Picton
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View article: A cross-sectional study of the role of epithelial cell injury in kidney transplant outcomes
A cross-sectional study of the role of epithelial cell injury in kidney transplant outcomes Open
Genome Canada; Natera, Inc.; and Thermo Fisher Scientific.
View article: Preventing kidney transplant failure by screening for antibodies against human leucocyte antigens followed by optimised immunosuppression: OuTSMART RCT
Preventing kidney transplant failure by screening for antibodies against human leucocyte antigens followed by optimised immunosuppression: OuTSMART RCT Open
Design Investigator-led, prospective, open-labelled marker-based strategy (hybrid) randomised trial. Background Allografts in 3% of kidney transplant patients fail annually. Development of antibodies against human leucocyte antigens is a v…
View article: Optimized immunosuppression to prevent graft failure in renal transplant recipients with HLA antibodies (OuTSMART): a randomised controlled trial
Optimized immunosuppression to prevent graft failure in renal transplant recipients with HLA antibodies (OuTSMART): a randomised controlled trial Open
View article: Can direct oral anticoagulants be used in kidney transplant recipients?
Can direct oral anticoagulants be used in kidney transplant recipients? Open
Background : Kidney transplant recipients(KTRs) are at an increased risk of venous thromboembolism (VTE) and atrial fibrillation(AF). Direct oral anticoagulants (DOACs) have shown important advantages over vitamin K antagonists; however, i…
View article: Living donor kidney transplantation: often a missed opportunity
Living donor kidney transplantation: often a missed opportunity Open
Kidney transplantation is the only treatment that provides a sustained cure for end stage renal failure (ESRF) and should be the treatment of choice for all eligible patients.1 Dialysis is the alternative renal replacement therapy, but is …
View article: Update to the study protocol, including statistical analysis plan, for the multicentre, randomised controlled OuTSMART trial: a combined screening/treatment programme to prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies
Update to the study protocol, including statistical analysis plan, for the multicentre, randomised controlled OuTSMART trial: a combined screening/treatment programme to prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies Open
ISRCTN registry, ID: ISRCTN46157828 . Registered on 26 March 2013; EudraCT 2012-004308-36 . Registered on 10 December 2012.
View article: A single-center experience of post-transplant lymphomas involving the central nervous system with a review of current literature
A single-center experience of post-transplant lymphomas involving the central nervous system with a review of current literature Open
This study supports observational data suggesting MMF treated patients without CNI may have increased risk of disease. Peripheral blood screening for EBV DNAemia does not seem helpful in early identification of those at risk.
View article: Dissolution of extensive urolithiasis: extending the utility of rasburicase can avoid the need for surgical intervention and renal replacement therapy
Dissolution of extensive urolithiasis: extending the utility of rasburicase can avoid the need for surgical intervention and renal replacement therapy Open
A 79-year-old male with chronic myelomonocytic leukaemia and extensive bilateral renal stone disease was treated with intravenous rasburicase for persistent hyperuricaemia. Subsequent imaging revealed a complete dissolution of stone burden…
View article: rhErythropoietin-b as a tissue protective agent in kidney transplantation: a pilot randomized controlled trial
rhErythropoietin-b as a tissue protective agent in kidney transplantation: a pilot randomized controlled trial Open