Michael Pratt
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View article: A bibliometric analysis of three decades of research on the correlates and determinants of physical activity in China
A bibliometric analysis of three decades of research on the correlates and determinants of physical activity in China Open
Objective: This study examines three decades of research progress on the correlates and determinants of physical activity in China, by analyzing the trends and characteristics of publications from 1990 to 2019. Methods: A systematic review…
View article: Progress in Physical Activity Surveillance, Research, and Policy in Mexico: The Global Observatory for Physical Activity
Progress in Physical Activity Surveillance, Research, and Policy in Mexico: The Global Observatory for Physical Activity Open
Introduction Physical inactivity is a global concern, linked to over 5 million annual deaths and a significant burden of noncommunicable diseases (NCDs). This study focuses on Mexico, where NCDs contribute to 80% of all deaths, reporting o…
View article: Physical Activity in Underserved Preadolescents
Physical Activity in Underserved Preadolescents Open
Objectives: The purpose of this study was to examine middle and high school students’ cognitive and affective attitude and their cognitive-affective attitudinal structures toward physical education (PE). The effects of cognitive and affect…
View article: Celebrating 10 Years of the Global Observatory for Physical Activity—GoPA!
Celebrating 10 Years of the Global Observatory for Physical Activity—GoPA! Open
The Global Observatory for Physical Activity (GoPA!) is a grass roots network consisting of many of the best physical activity researchers, policy makers and practitioners from around the world. 1 As an independent, democratic, and informa…
View article: Gender Differences in Physical Activity and Health-Related Authorships Between 1950 and 2019
Gender Differences in Physical Activity and Health-Related Authorships Between 1950 and 2019 Open
Background : The objective of this study was to investigate gender differences in authorship in physical activity and health research. Methods : A bibliometric study including 23,399 articles from 105 countries was conducted to estimate th…
View article: Where Are Czech Adolescents Active? The Patterns of Movement and Transport Behavior in Different Active Living Domains
Where Are Czech Adolescents Active? The Patterns of Movement and Transport Behavior in Different Active Living Domains Open
To understand the environmental determinants of physical activity (PA), precise spatial localization is crucial. This cross-sectional study focuses on the spatiotemporal distribution of PA among Czech adolescents (n = 171) using Global Pos…
View article: Physical Activity Policies at National and Subnational Levels: A Study in Colombia, Costa Rica, Ecuador, and Mexico
Physical Activity Policies at National and Subnational Levels: A Study in Colombia, Costa Rica, Ecuador, and Mexico Open
Background: National physical activity (PA) policy processes are only beginning to be studied in Latin America, and little attention has focused at the subnational level. This study examined national–subnational relations in the policy pro…
View article: Breaking Barriers: An Innovative Tool to Assess the National and City-Level Physical Activity Policy Development to Practice Disconnect
Breaking Barriers: An Innovative Tool to Assess the National and City-Level Physical Activity Policy Development to Practice Disconnect Open
Background : Population-level physical activity increases are improbable without intersectoral collaboration across government levels and sectors to develop and implement physical activity promotion policies. This study aims to provide inf…
View article: Shaping Policy and Practice: Analyzing the Reach of Highly Cited and High Altmetrics Publications for Broader Impact on Physical Activity
Shaping Policy and Practice: Analyzing the Reach of Highly Cited and High Altmetrics Publications for Broader Impact on Physical Activity Open
Background: A significant gap remains between the availability of physical activity (PA) evidence-based interventions and their application in real-world settings in policy and practice areas. This study aims to describe highly cited and h…
View article: O.6.2-3 The Global Observatory for Physical Education (GoPE!): monitoring physical education and physical activity in children and adolescents worldwide
O.6.2-3 The Global Observatory for Physical Education (GoPE!): monitoring physical education and physical activity in children and adolescents worldwide Open
Purpose It is estimated that 80% of children and adolescents do not meet the 60 min of moderate-to-vigorous intensity physical activity (PA) per day to benefit their health.1,2 Strengthening the provision of quality physical education (PE)…
View article: O.1.3-2 Development and implementation of physical activity policies at national and subnational levels: a pilot study in Latin American countries
O.1.3-2 Development and implementation of physical activity policies at national and subnational levels: a pilot study in Latin American countries Open
Purpose National physical activity (PA) policy processes are only beginning to be documented, and the interaction between the actors involved in these processes remains understudied. This study was designed to gain further insights into th…
View article: Availability of Recreation Facilities and Parks In Relation to Adolescent Participation in Organized Sports and Activity Programs
Availability of Recreation Facilities and Parks In Relation to Adolescent Participation in Organized Sports and Activity Programs Open
Most adolescents do not meet physical activity guidelines, so understanding facilitators and barriers is important. This study used surveys and geocoded location data to examine associations of availability of parks and recreation faciliti…
View article: Summary of the IC50s of Delta-24-RGD in Tested Pancreatic Cancer Cell Lines from Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma
Summary of the IC50s of Delta-24-RGD in Tested Pancreatic Cancer Cell Lines from Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma Open
This table summarizes the dose (multiplicity of infection, MOI) of Delta-24-RGD that causes 50% of viability inhibition of infected pancreatic cancer cell lines (IC50).
View article: Data from Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma
Data from Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma Open
Delta-24-RGD (DNX-2401) is a conditional replication-competent oncolytic virus engineered to preferentially replicate in and lyse tumor cells with abnormality of p16/RB/E2F pathway. In a phase I clinical trial, Delta-24-RGD has shown favor…
View article: Summary of the IC50s of Delta-24-RGD in Tested Pancreatic Cancer Cell Lines from Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma
Summary of the IC50s of Delta-24-RGD in Tested Pancreatic Cancer Cell Lines from Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma Open
This table summarizes the dose (multiplicity of infection, MOI) of Delta-24-RGD that causes 50% of viability inhibition of infected pancreatic cancer cell lines (IC50).
View article: Supplementary Materials and Methods from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors
Supplementary Materials and Methods from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors Open
HPaSteC and Media: Western blot and ELISA assay: Vectra Automated Quantitative Pathology Imaging System (VAQPIS, PerkinElmer): Double Immunofluorescence staining (IF), and Vectra multispectral analysis: Supplementary figure legends:
View article: Supplementary tables from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors
Supplementary tables from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors Open
Supplementary Table 1. Wild type and mutant lumican SBE oligos for EMSA. Supplementary Table 2. Clinicopathologic and oncologic outcome correlation of stromal lumican expression in PDAC. Supplementary Table 3. Amount of Lumican Secretion i…
View article: Supplementary figure 4 from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors
Supplementary figure 4 from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors Open
PDAC cells matrix adhesions were affect by HPSC supernatant of 24 hour's collection.
View article: Supplementary figure 1 from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors
Supplementary figure 1 from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors Open
Vectra Image analysis workflow, Double IF staining of lumican and collagen I, and TGF-β secretion in HPSC.
View article: Supplemental Methods and Supplemental Figure 1 Legend from <i>Ex Vivo</i> Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma
Supplemental Methods and Supplemental Figure 1 Legend from <i>Ex Vivo</i> Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma Open
Supplemental Materials and Methods: Immunohistochemical staining of cleaved caspase 3, statistical analysis of the correlation of LTSA values with patients' progression free survival; Supplemental Figure legend
View article: Data from <i>Ex Vivo</i> Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma
Data from <i>Ex Vivo</i> Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma Open
Purpose: Translation of the patient-derived xenograft (PDX) model into a method for practical personalized cancer treatment is prevented by the intense resources and time necessary to generate and test each tumorgraft. We aimed to develop …
View article: Supplementary figure 2 from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors
Supplementary figure 2 from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors Open
Lumican expression and secretion in HPaSteC with or without TGF-β exposure at 8 and 24 hours.
View article: Supplementary Figure 1 from <i>Ex Vivo</i> Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Figure 1 from <i>Ex Vivo</i> Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma Open
Tissue slices after treatment with Gemcitabine (100 µM) or Irinotecan (30 µM) for 48 hours were fixed and embedded for immunohistochemical staining of cleaved-Caspase 3 (40X magnification, Bars = 20 µm).
View article: Supplementary figure 1 from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors
Supplementary figure 1 from Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors Open
Vectra Image analysis workflow, Double IF staining of lumican and collagen I, and TGF-β secretion in HPSC.
View article: Supplemental Methods and Supplemental Figure 1 Legend from <i>Ex Vivo</i> Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma
Supplemental Methods and Supplemental Figure 1 Legend from <i>Ex Vivo</i> Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma Open
Supplemental Materials and Methods: Immunohistochemical staining of cleaved caspase 3, statistical analysis of the correlation of LTSA values with patients' progression free survival; Supplemental Figure legend
View article: Supplementary Figure 1 from <i>Ex Vivo</i> Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Figure 1 from <i>Ex Vivo</i> Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma Open
Tissue slices after treatment with Gemcitabine (100 µM) or Irinotecan (30 µM) for 48 hours were fixed and embedded for immunohistochemical staining of cleaved-Caspase 3 (40X magnification, Bars = 20 µm).