2025-06-27
Inhibition of Urea Hydrolysis in Human Urine for Resource and Energy Recovery: Pharmaceuticals and Their Metabolites as Co-Existing Anticatalyzers
2025-06-27 • H. Chi, Minshu Chen, Wei Yang, LI Ya, Shuhui Sun, Hualin Wang, Xuejing Yang, Michael R. Hoffmann, Lei Guo
Urine, which has a high concentration of urea, can be used as a sustainable resource for nutrient recovery and sustainable energy. However, urea undergoes hydrolysis, catalyzed by urease, generating ammonia and carbon dioxide. As ammonia is released during hydrolysis in stored urine, the pH rises progressively until the pKa of ammonium is reached (i.e., 9.3). At elevated pH levels, struvite and other related precipitates are formed. These reactions lower the efficiency of ammonia and urea nitrogen recovery and oft…