Michael R. Skilton
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View article: Maternal and child predictors of vascular health in infancy and early childhood
Maternal and child predictors of vascular health in infancy and early childhood Open
Background Excessive weight gain (EWG) in childhood may increase cardiovascular disease risk in adulthood, but its relationship to early vascular health remains poorly understood. This study investigated the relationship between EWG and ao…
View article: Healthy ageing
Healthy ageing Open
View article: A cross-sectional study of non-invasive markers of vascular health in children and adolescents
A cross-sectional study of non-invasive markers of vascular health in children and adolescents Open
Background Non-invasive methods assessing subclinical atherosclerosis, such as carotid intima-media thickness (IMT) and carotid-femoral pulse wave velocity (cfPWV), are well-described in adults but less so in the paediatric population. Oth…
View article: Associations between dietary macronutrient composition and cardiometabolic health: data from NHANES 1999–2014
Associations between dietary macronutrient composition and cardiometabolic health: data from NHANES 1999–2014 Open
View article: Intergenerational equity and the health of Australia's young people
Intergenerational equity and the health of Australia's young people Open
View article: The crux of modern health care challenges
The crux of modern health care challenges Open
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View article: The Relationship between Dietary Macronutrient Composition and Telomere Length Among US Adults
The Relationship between Dietary Macronutrient Composition and Telomere Length Among US Adults Open
The role of dietary macronutrients and energy intake in the aging process has been well‐established. However, previous research has mainly focused on the association between leukocyte telomere length (LTL) and individual macronutrients, wh…
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View article: P107 Optimizing Obstructive Sleep Apnea Therapy in Patients with Acute Coronary Syndrome: A Pilot Randomised Controlled Trial
P107 Optimizing Obstructive Sleep Apnea Therapy in Patients with Acute Coronary Syndrome: A Pilot Randomised Controlled Trial Open
Continuous positive airway pressure (CPAP) therapy and oral appliance therapy (OAT) are recommended therapies for obstructive sleep apnoea (OSA). Recent clinical trials, limited by suboptimal implementation of OSA therapy, have demonstrate…
View article: P108 Obstructive Sleep Apnoea in Acute Coronary Syndrome: An Observational Study
P108 Obstructive Sleep Apnoea in Acute Coronary Syndrome: An Observational Study Open
Obstructive sleep apnoea (OSA) is a risk factor for cardiovascular disease. CPAP therapy is the primary treatment for OSA and is known to improve long term cardiovascular health outcomes. Recent neutral findings of randomised clinical tria…
View article: O037 Diagnostic Accuracy of OSA Screening Tools for Acute Coronary Syndrome
O037 Diagnostic Accuracy of OSA Screening Tools for Acute Coronary Syndrome Open
Obstructive sleep apnoea(OSA) is associated with cardiovascular diseases including acute coronary syndrome(ACS). Current estimates suggest some 70% of patients with ACS have OSA. OSA in this population remains under-recognised. This high p…
View article: Intima-media thickness at the near or far wall of the common carotid artery in cardiovascular risk assessment
Intima-media thickness at the near or far wall of the common carotid artery in cardiovascular risk assessment Open
Aims Current guidelines recommend measuring carotid intima-media thickness (IMT) at the far wall of the common carotid artery (CCA). We aimed to precisely quantify associations of near vs. far wall CCA-IMT with the risk for atherosclerotic…
View article: Cardiovascular disease risk factors and their association with peripheral and central blood pressures in children and adolescents
Cardiovascular disease risk factors and their association with peripheral and central blood pressures in children and adolescents Open
View article: P19-025-23 Macronutrient Composition of Plant-Based Diets and Breast Cancer Risk: The E3N Prospective Cohort Study
P19-025-23 Macronutrient Composition of Plant-Based Diets and Breast Cancer Risk: The E3N Prospective Cohort Study Open
View article: Association of Intima‐Media Thickness Measured at the Common Carotid Artery With Incident Carotid Plaque: Individual Participant Data Meta‐Analysis of 20 Prospective Studies
Association of Intima‐Media Thickness Measured at the Common Carotid Artery With Incident Carotid Plaque: Individual Participant Data Meta‐Analysis of 20 Prospective Studies Open
Background The association between common carotid artery intima‐media thickness (CCA‐IMT) and incident carotid plaque has not been characterized fully. We therefore aimed to precisely quantify the relationship between CCA‐IMT and carotid p…
View article: Cohort profile: the BABY1000 pilot prospective longitudinal birth cohort study based in Sydney, Australia
Cohort profile: the BABY1000 pilot prospective longitudinal birth cohort study based in Sydney, Australia Open
Purpose The health of parents prior to conception, a woman’s health during pregnancy and the infant’s environment across their first months and years collectively have profound effects on the child’s health across the lifespan. Since there…
View article: Diet Quality, Microbial Lignan Metabolites, and Cardiometabolic Health among US Adults
Diet Quality, Microbial Lignan Metabolites, and Cardiometabolic Health among US Adults Open
The gut microbiome has been shown to play a role in the relationship between diet and cardiometabolic health. We sought to examine the degree to which key microbial lignan metabolites are involved in the relationship between diet quality a…
View article: Multi-Nutrient Analysis of Dietary Macronutrients with All-Cause, Cardiovascular, and Cancer Mortality: Data from NHANES 1999–2014
Multi-Nutrient Analysis of Dietary Macronutrients with All-Cause, Cardiovascular, and Cancer Mortality: Data from NHANES 1999–2014 Open
Macronutrients are a major component of the human diet. However, few studies have assessed their collective association with mortality. We sought to evaluate the associations of macronutrient intake with all-cause, cardiovascular, and canc…
View article: Dietary Patterns and Non-Communicable Disease Biomarkers: A Network Meta-Analysis and Nutritional Geometry Approach
Dietary Patterns and Non-Communicable Disease Biomarkers: A Network Meta-Analysis and Nutritional Geometry Approach Open
Quantitative rankings of multiple dietary patterns for their effects on non-communicable disease (NCD) biomarkers is lacking and would inform primary prevention strategies. Accordingly, a network meta-analysis (NMA) was conducted to compar…
View article: Intrauterine exposure to preeclampsia does not impair vascular health in children
Intrauterine exposure to preeclampsia does not impair vascular health in children Open
Background and objectives Preeclampsia is a serious multisystem blood pressure disorder during pregnancy that is associated with increased long-term risk of cardiovascular disease to the mother and offspring. We investigated the vascular h…
View article: Infants With Congenital Heart Disease at Risk of Early Atherosclerotic Disease
Infants With Congenital Heart Disease at Risk of Early Atherosclerotic Disease Open
Background Aortic intima‐media thickness (aIMT) measurement is an established indicator of preclinical atherosclerosis. We aimed to describe the aIMT in infants with congenital heart disease undergoing cardiac surgery over the first year o…
View article: Associations of dietary macronutrient composition with cardiometabolic health: data from the National Health and Nutrition Examination Survey (NHANES) 1999–2014
Associations of dietary macronutrient composition with cardiometabolic health: data from the National Health and Nutrition Examination Survey (NHANES) 1999–2014 Open
Background Human nutrition is a leading modifiable risk factor for the prevention of cardiometabolic diseases. However, most nutritional research focuses on the role of specific nutrients rather than compositional analysis of the diet. Pur…
View article: Early life determinants of vascular structure in foetuses, infants, children and adolescents: A systematic review and meta-analysis
Early life determinants of vascular structure in foetuses, infants, children and adolescents: A systematic review and meta-analysis Open