Michael S. Lloyd
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View article: Perspective Chapter: The Future of Wholesale CBDCs in a Tokenizing and Trumpian World
Perspective Chapter: The Future of Wholesale CBDCs in a Tokenizing and Trumpian World Open
Globally, the private sector is moving towards expanding the growth of tokenized assets trading, using private money channels (stablecoins) as payment systems. At the same time, the public sector, often central banks in alliance with priva…
View article: Spontaneous arrhythmic episodes in the study of a modular, communicative, leadless pacing-defibrillator system (Modular ATP trial)
Spontaneous arrhythmic episodes in the study of a modular, communicative, leadless pacing-defibrillator system (Modular ATP trial) Open
Background MODULAR ATP, a multicenter, international trial, assesses a subcutaneous ICD (S-ICD) in wireless communication to a leadless pacemaker (LP) capable of pace terminating ventricular arrhythmias in addition to providing shock thera…
View article: Preclinical evaluation of safety and efficacy of the Coherent Sine-Burst Electroporation (CSE) ablation system in a chronic porcine beating heart model
Preclinical evaluation of safety and efficacy of the Coherent Sine-Burst Electroporation (CSE) ablation system in a chronic porcine beating heart model Open
Background First-generation Pulsed Field Ablation (PFA) technologies implement square waveforms delivered via focal, multi-spline, or basket catheter designs. Coherent Sine-Burst Electroporation (CSE) is a novel PFA platform that uses cohe…
View article: Sustained Monomorphic Ventricular Tachycardia Accurately Detected by Wearable Technology
Sustained Monomorphic Ventricular Tachycardia Accurately Detected by Wearable Technology Open
Wearable devices are increasingly used to detect arrhythmias, including life-threatening ventricular tachycardia (VT). This case highlights their role in clinical settings. A patient with prior surgical aortic valve replacement because of …
View article: A Kratomic Bomb
A Kratomic Bomb Open
View article: First-in-Human Helical-Fixation Leadless Pacemaker in the Left Atrium for D-Transposition With Atrial Switch Procedure
First-in-Human Helical-Fixation Leadless Pacemaker in the Left Atrium for D-Transposition With Atrial Switch Procedure Open
View article: Machine Learning-Based Identification of High-Risk Patterns in Atrial Fibrillation Ablation Outcomes
Machine Learning-Based Identification of High-Risk Patterns in Atrial Fibrillation Ablation Outcomes Open
Background Atrial fibrillation (AF) is one of the most common types of cardiac arrhythmias, often leading to serious health issues such as stroke, heart failure, and higher mortality rates. Its global impact is rising due to aging populati…
View article: Trends and Disparities in Atrial Fibrillation and Stroke Related Mortality in the United States from 1999 to 2020
Trends and Disparities in Atrial Fibrillation and Stroke Related Mortality in the United States from 1999 to 2020 Open
View article: Predicting Atrial Fibrillation Ablation Outcomes: A Machine Learning Approach Leveraging a Large Administrative Claims Database
Predicting Atrial Fibrillation Ablation Outcomes: A Machine Learning Approach Leveraging a Large Administrative Claims Database Open
Background Atrial fibrillation (AF) ablation is an effective treatment for reducing episodes and improving quality of life in patients with AF. However, in some patients there are only modest long-term AF-free rates after AF ablation. Ther…
View article: Costs, efficiency, and patient‐reported outcomes associated with suture‐mediated percutaneous closure for atrial fibrillation ablation: Secondary analysis of a randomized clinical trial
Costs, efficiency, and patient‐reported outcomes associated with suture‐mediated percutaneous closure for atrial fibrillation ablation: Secondary analysis of a randomized clinical trial Open
Introduction To evaluate the cost and efficiency of suture‐mediated percutaneous closure (SMC) compared to manual compression (MC) after atrial fibrillation (AF) ablation. SMC has been demonstrated to be efficacious in reducing hemostasis …
View article: Patient selection, ventricular tachycardia substrate delineation, and data transfer for stereotactic arrhythmia radioablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society
Patient selection, ventricular tachycardia substrate delineation, and data transfer for stereotactic arrhythmia radioablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society Open
Stereotactic arrhythmia radioablation (STAR) is a novel, non-invasive, and promising treatment option for ventricular arrhythmias (VAs). It has been applied in highly selected patients mainly as bailout procedure, when (multiple) catheter …
View article: PO-02-034 CARDIOGENIC SHOCK AND PNEUMOPERICARDIUM: A RARE PRESENTATION OF ATRIOESOPHAGEAL FISTULA
PO-02-034 CARDIOGENIC SHOCK AND PNEUMOPERICARDIUM: A RARE PRESENTATION OF ATRIOESOPHAGEAL FISTULA Open
View article: Percutaneous Transpericardial Permanent Pacing in a Woman With Fontan Circulation
Percutaneous Transpericardial Permanent Pacing in a Woman With Fontan Circulation Open
View article: Rising burden of cardiac arrest– and heart failure–related mortality in the United States from 1999 to 2020
Rising burden of cardiac arrest– and heart failure–related mortality in the United States from 1999 to 2020 Open
View article: Safety of multi-access site venous closure following catheter ablation of atrial fibrillation and flutter
Safety of multi-access site venous closure following catheter ablation of atrial fibrillation and flutter Open
Background Following catheter ablation, vascular access management involves potential complications and prolonged recovery. Recently, suture-mediated closure (SMC) devices were approved for venous access procedures. The objective of this s…
View article: Long-Term Outcomes of Cardiac Resynchronization Therapy in Patients With Repaired Tetralogy of Fallot: A Multicenter Study
Long-Term Outcomes of Cardiac Resynchronization Therapy in Patients With Repaired Tetralogy of Fallot: A Multicenter Study Open
BACKGROUND: A growing number of patients with tetralogy of Fallot develop left ventricular systolic dysfunction and heart failure, in addition to right ventricular dysfunction. Although cardiac resynchronization therapy (CRT) is an establi…
View article: A Patient‐Centered Approach to Cardiac Monitoring After Cryptogenic Stroke: A Review
A Patient‐Centered Approach to Cardiac Monitoring After Cryptogenic Stroke: A Review Open
Due to the variety of cardiac monitoring devices available after cryptogenic stroke to screen for atrial fibrillation, there is a need to understand the challenges and perceptions of these devices for patients. This article reviews in deta…
View article: Accurate Detection of Lead Malfunction From ECG-derived Bipolar Pacing Stimulus Amplitude
Accurate Detection of Lead Malfunction From ECG-derived Bipolar Pacing Stimulus Amplitude Open
Background One of the most common modes of lead failure is outer insulation breach which may result in myopotential noise and device malfunction. “Pseudo-unipolarization” of bipolar pacing stimuli, as observed from a routine 12-lead ECG ha…
View article: Complex repolarization dynamics in <i>ex vivo</i> human ventricles are independent of the restitution properties
Complex repolarization dynamics in <i>ex vivo</i> human ventricles are independent of the restitution properties Open
Aims The mechanisms of transition from regular rhythms to ventricular fibrillation (VF) are poorly understood. The concordant to discordant repolarization alternans pathway is extensively studied; however, despite its theoretical centralit…
View article: Long-term performance of single-connector (DF4) implantable defibrillator leads
Long-term performance of single-connector (DF4) implantable defibrillator leads Open
Aims Single-connector (DF4) defibrillator leads have become the predominantly implanted transvenous implantable cardioverter-defibrillator lead. However, data on their long-term performance are derived predominantly from manufacturer produ…
View article: Outcomes of Tricuspid Regurgitation After Lead Extraction
Outcomes of Tricuspid Regurgitation After Lead Extraction Open
Background: Transvenous leads have been implicated in tricuspid valve (TV) dysfunction, but limited data are available regarding the effect of extracting leads across the TV on valve regurgitation. Objective: The aim of this study is to qu…
View article: Interobserver variability in target definition for stereotactic arrhythmia radioablation
Interobserver variability in target definition for stereotactic arrhythmia radioablation Open
Background Stereotactic arrhythmia radioablation (STAR) is a potential new therapy for patients with refractory ventricular tachycardia (VT). The arrhythmogenic substrate (target) is synthesized from clinical and electro-anatomical informa…
View article: Septal Bipolar Ablation to Prevent Left Ventricular Outflow Tract Obstruction After Transcatheter Mitral Valve Implantation
Septal Bipolar Ablation to Prevent Left Ventricular Outflow Tract Obstruction After Transcatheter Mitral Valve Implantation Open
View article: Clinical outcomes of automatic algorithms in cardiac resynchronization therapy: Systematic review and meta-analysis
Clinical outcomes of automatic algorithms in cardiac resynchronization therapy: Systematic review and meta-analysis Open
Automatic algorithms that change AV or VV intervals did not improve mortality, heart failure hospitalizations, or cardiovascular symptoms in patients with heart failure and CRT.
View article: Novel Smart N95 Filtering Facepiece Respirator with Real-time Adaptive Fit Functionality and Wireless Humidity Monitoring for Enhanced Wearable Comfort
Novel Smart N95 Filtering Facepiece Respirator with Real-time Adaptive Fit Functionality and Wireless Humidity Monitoring for Enhanced Wearable Comfort Open
The widespread emergence of the COVID-19 pandemic has transformed our lifestyle, and facial respirators have become an essential part of daily life. Nevertheless, the current respirators possess several limitations such as poor respirator …
View article: Higher-Order Dynamics Beyond Repolarization Alternans in Ex-Vivo Human Ventricles are Independent of the Restitution Properties
Higher-Order Dynamics Beyond Repolarization Alternans in Ex-Vivo Human Ventricles are Independent of the Restitution Properties Open
Background Repolarization alternans, defined as period-2 oscillation in the repolarization phase of the action potentials, provides a mechanistic link between cellular dynamics and ventricular fibrillation (VF). Theoretically, higher-order…
View article: Rationale and Design of the Multicenter Catheter Ablation of Ventricular Tachycardia Before Transcatheter Pulmonary Valve Replacement in Repaired Tetralogy of Fallot Study
Rationale and Design of the Multicenter Catheter Ablation of Ventricular Tachycardia Before Transcatheter Pulmonary Valve Replacement in Repaired Tetralogy of Fallot Study Open
Patients with repaired tetralogy of Fallot are at elevated risk for ventricular arrhythmia and sudden cardiac death. Over the past decade, the pathogenesis and natural history of ventricular tachycardia has become increasingly understood, …
View article: Design and characteristics of the prophylactic intra‐operative ventricular arrhythmia ablation in high‐risk LVAD candidates (PIVATAL) trial
Design and characteristics of the prophylactic intra‐operative ventricular arrhythmia ablation in high‐risk LVAD candidates (PIVATAL) trial Open
Background The use of a Left Ventricular Assist Device (LVAD) in patients with advanced heart failure refractory to optimal medical management has progressed steadily over the past two decades. Data have demonstrated reduced LVAD efficacy,…
View article: RyR2 C-terminal truncating variants identified in patients with arrhythmic phenotypes exert a dominant negative effect through formation of wildtype-truncation heteromers
RyR2 C-terminal truncating variants identified in patients with arrhythmic phenotypes exert a dominant negative effect through formation of wildtype-truncation heteromers Open
Gain-of-function missense variants in the cardiac ryanodine receptor (RyR2) are linked to catecholaminergic polymorphic ventricular tachycardia (CPVT), whereas RyR2 loss-of-function missense variants cause Ca2+ release deficiency syndrome …
View article: Design and rationale of the MODULAR ATP global clinical trial: A novel intercommunicative leadless pacing system and the subcutaneous implantable cardioverter-defibrillator
Design and rationale of the MODULAR ATP global clinical trial: A novel intercommunicative leadless pacing system and the subcutaneous implantable cardioverter-defibrillator Open