Michaël Sauthier
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View article: Intensive Care Unit Monitoring Post-Tonsillectomy in Children with Obstructive Sleep Apnea
Intensive Care Unit Monitoring Post-Tonsillectomy in Children with Obstructive Sleep Apnea Open
Objective There is a lack of consensus regarding postoperative care for pediatric patients with obstructive sleep apnea (OSA) following adenotonsillectomy. At our institution, all patients with severe OSA are routinely admitted to the pedi…
View article: Developing and validating an accelerated online Canadian training in data science for the health sciences community
Developing and validating an accelerated online Canadian training in data science for the health sciences community Open
Background With the rise of digital health, proficiency in data science is becoming increasingly important. University curricula often lack adequate data analysis and programming education, hence the need to develop an accessible training …
View article: A Continuous and Noninvasive Method to Estimate Pao 2/Fio 2 Ratio
A Continuous and Noninvasive Method to Estimate Pao 2/Fio 2 Ratio Open
OBJECTIVES: To validate a method for continuously estimating the Pa o 2 /F io 2 (PF) ratio in all critically ill pediatric patients using only standard continuous data monitoring. DESIGN: Retrospective study on a high temporal resolution d…
View article: CODA: an open-source platform for federated analysis and machine learning on distributed healthcare data
CODA: an open-source platform for federated analysis and machine learning on distributed healthcare data Open
Objectives Distributed computations facilitate multi-institutional data analysis while avoiding the costs and complexity of data pooling. Existing approaches lack crucial features, such as built-in medical standards and terminologies, no-c…
View article: Clinical Decision Support System to Detect the Occurrence of Ventilator-Associated Pneumonia in Pediatric Intensive Care
Clinical Decision Support System to Detect the Occurrence of Ventilator-Associated Pneumonia in Pediatric Intensive Care Open
Objectives: Ventilator-associated pneumonia (VAP) is a severe care-related disease. The Centers for Disease Control defined the diagnosis criteria; however, the pediatric criteria are mainly subjective and retrospective. Clinical decision …
View article: Evaluation of the SIMULRESP: A simulation software of child and teenager cardiorespiratory physiology
Evaluation of the SIMULRESP: A simulation software of child and teenager cardiorespiratory physiology Open
Background Mathematical models based on the physiology when programmed as a software can be used to teach cardiorespiratory physiology and to forecast the effect of various ventilatory support strategies. We developed a cardiorespiratory s…
View article: Evaluating the Need for Intensive Care Admission After Supraglottoplasty for Severe Laryngomalacia
Evaluating the Need for Intensive Care Admission After Supraglottoplasty for Severe Laryngomalacia Open
Objective Postoperative airway concerns persist despite a low rate of post‐supraglottoplasty complications for children with laryngomalacia. The objective of this study is to determine the factors associated with the need for intensive car…
View article: Automated screening of potential organ donors using a temporal machine learning model
Automated screening of potential organ donors using a temporal machine learning model Open
Organ donation is not meeting demand, and yet 30–60% of potential donors are potentially not identified. Current systems rely on manual identification and referral to an Organ Donation Organization (ODO). We hypothesized that developing an…
View article: Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2)
Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2) Open
OBJECTIVES: We sought to update our 2015 work in the Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guidelines for the diagnosis and management of pediatric acute respiratory distress syndrome (PARDS), considering new e…
View article: Evaluation of the SIMULRESP: a simulation software of child and teenager cardiorespiratory physiology
Evaluation of the SIMULRESP: a simulation software of child and teenager cardiorespiratory physiology Open
BACKGROUND: Mathematical models based on the physiology when programmed as a software can be used to teach cardiorespiratory physiology and to forecast the effect of various ventilatory support strategies. We developed a cardiorespiratory …
View article: Intravenous Immunoglobulin Use In Critically Ill Children
Intravenous Immunoglobulin Use In Critically Ill Children Open
Purpose The use of intravenous immunoglobulins (IVIG) has increased significantly in the last decade causing challenges for blood suppliers to respond to the demand. Indications for which IVIG infusion should be given to critically ill chi…
View article: Estimated Pao 2: A Continuous and Noninvasive Method to Estimate Pao 2 and Oxygenation Index
Estimated Pao 2: A Continuous and Noninvasive Method to Estimate Pao 2 and Oxygenation Index Open
BACKGROUND: Pa o 2 is the gold standard to assess acute hypoxic respiratory failure, but it is only routinely available by intermittent spot checks, precluding any automatic continuous analysis for bedside tools. OBJECTIVE: To validate a c…
View article: Long-Term Mechanical Ventilation in Neonates: A 10-Year Overview and Predictive Model
Long-Term Mechanical Ventilation in Neonates: A 10-Year Overview and Predictive Model Open
Objectives: Significant resources are devoted to neonatal prolonged mechanical ventilation (NPMV), but little is known about the outcomes in those children. Our primary objective was to describe the NPMV respiratory, digestive, and neurolo…
View article: Machine Learning Predicts Prolonged Acute Hypoxemic Respiratory Failure in Pediatric Severe Influenza
Machine Learning Predicts Prolonged Acute Hypoxemic Respiratory Failure in Pediatric Severe Influenza Open
Background: Influenza virus is a major cause of acute hypoxemic respiratory failure. Early identification of patients who will suffer severe complications can help stratify patients for clinical trials and plan for resource use in case of …
View article: Validation Process of a High-Resolution Database in a Pediatric Intensive Care Unit -- Describing the Perpetual Patient's Validation
Validation Process of a High-Resolution Database in a Pediatric Intensive Care Unit -- Describing the Perpetual Patient's Validation Open
Objective: High data quality is essential to ensure the validity of clinical and research inferences based on it. However, these data quality assessments are often missing even though these data are used in daily practice and research. Our…
View article: Using machine learning models to predict oxygen saturation following ventilator support adjustment in critically ill children: A single center pilot study
Using machine learning models to predict oxygen saturation following ventilator support adjustment in critically ill children: A single center pilot study Open
This single center pilot study using machine learning predictive model resulted in an algorithm with poor accuracy. The comparison of machine learning models showed that bagged complex trees was a promising approach. However, there is a ne…
View article: Using machine learning models to predict oxygen saturation following ventilator support adjustment in critically ill children: a single center pilot study
Using machine learning models to predict oxygen saturation following ventilator support adjustment in critically ill children: a single center pilot study Open
Clinicians’ experts in mechanical ventilation are not continuously at each patient’s bedside in an intensive care unit to adjust mechanical ventilation settings and to analyze the impact of ventilator settings adjustments on gas exchange. …
View article: Pediatric Prolonged Mechanical Ventilation: Considerations for Definitional Criteria
Pediatric Prolonged Mechanical Ventilation: Considerations for Definitional Criteria Open
Therefore, we developed the following recommendations for the pediatric PMV definition: ≥ 21 consecutive days (after 37 weeks postmenstrual age) of ventilation for ≥ 6 h/d considering invasive ventilation and NIV and including short interr…
View article: Impact of Electronic Data on the Development of Care in Critically Ill Children
Impact of Electronic Data on the Development of Care in Critically Ill Children Open
Major changes are occurring in pediatric intensive care due to the transition from paper to electronic clinical data collection. In this supplement of the Journal of Pediatric Intensive Care, a panel of experts review the literature and re…
View article: Perpetual and Virtual Patients for Cardiorespiratory Physiological Studies
Perpetual and Virtual Patients for Cardiorespiratory Physiological Studies Open
As a result of innovations in informatics over the last decades, physiologic models elaborated in the second half of the 20th century could be transformed into specific virtual patients called computational models. These models, developed …