Michael Schlegelmilch
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View article: Intravenous ketamine for emergency department treatment of suicidal ideation in a paediatric population: protocol for a double-blind, randomised, placebo-controlled, parallel-arm pilot trial (KSI study)
Intravenous ketamine for emergency department treatment of suicidal ideation in a paediatric population: protocol for a double-blind, randomised, placebo-controlled, parallel-arm pilot trial (KSI study) Open
Introduction Suicidal ideation (SI) is a common and severe cause of morbidity in adolescents. Patients frequently present to the emergency department (ED) for care, yet there is no acute therapeutic intervention for SI. A single dose of in…
View article: Case series of infants presenting to the emergency department with fever, bulging anterior fontanelle and COVID-19 infection
Case series of infants presenting to the emergency department with fever, bulging anterior fontanelle and COVID-19 infection Open
We present a three patient case series of infants who presented to the pediatric emergency department with fever, bulging anterior fontanelle (BAF), and an omicron variant COVID-19 infection. All patients had a benign course, none develope…
View article: Inadvertent Acute Lipid Injectable Emulsion Overdose Resulting in Fat Overload Syndrome and Pancreatitis in a Patient with TPN Dependence
Inadvertent Acute Lipid Injectable Emulsion Overdose Resulting in Fat Overload Syndrome and Pancreatitis in a Patient with TPN Dependence Open
We report a case of an acute, inadvertent, 7.5‐fold intravenous lipid emulsion overdose with 20% SMOFlipid in an 11‐month‐old female with tetratricopeptide repeat domain 7A (TTC7A) mutation, intestinal failure, and parenteral nutrition dep…
View article: Comparative Effectiveness of Pediatric Integrative Medicine: A Pragmatic Cluster-Controlled Trial
Comparative Effectiveness of Pediatric Integrative Medicine: A Pragmatic Cluster-Controlled Trial Open
Symptoms of pain, nausea/vomiting, and anxiety (PNVA) are highly prevalent in pediatric inpatients. Poorly managed symptoms can lead to decreased compliance with care, and prolonged recovery times. Pharmacotherapy used to manage PNVA sympt…
View article: Considerations for the use and study of exogenous surfactant in respiratory disease from COVID-19
Considerations for the use and study of exogenous surfactant in respiratory disease from COVID-19 Open
Exogenous surfactant therapy has been widely studied in acute respiratory distress syndrome (ARDS) but has failed to show mortality benefit in several trials. The COVID-19 pandemic has renewed interest in exogenous surfactant, and clinical…
View article: 84 Impact of young age on outcomes of emergency department procedural sedation
84 Impact of young age on outcomes of emergency department procedural sedation Open
Background Procedural sedation in the emergency department (ED) for children undergoing painful procedures is common practice, however little is known about sedation in very young children. Objectives We examined the effect of young age on…
View article: Observational Study of Pediatric Inpatient Pain, Nausea/Vomiting and Anxiety
Observational Study of Pediatric Inpatient Pain, Nausea/Vomiting and Anxiety Open
Background: The prevalence and severity of pain, nausea/vomiting, and anxiety (PNVA) among hospitalized children is not well established. We describe the prevalence and severity of PNVA among hospitalized patients from oncology, general pe…
View article: P116: Impact of young age on outcomes of emergency department procedural sedation
P116: Impact of young age on outcomes of emergency department procedural sedation Open
View article: Corrigendum to “Comparative effectiveness of pediatric integrative medicine as an adjunct to usual care for pediatric inpatients of a North American tertiary care centre: A study protocol for a pragmatic cluster controlled trial” [Contemp. Clin. Trials Commun. (2017) 12–18]
Corrigendum to “Comparative effectiveness of pediatric integrative medicine as an adjunct to usual care for pediatric inpatients of a North American tertiary care centre: A study protocol for a pragmatic cluster controlled trial” [Contemp. Clin. Trials Commun. (2017) 12–18] Open
View article: Cost-Effectiveness Analysis of Total Hip Arthroplasty Performed by a Canadian Short-Stay Surgical Team in Ecuador
Cost-Effectiveness Analysis of Total Hip Arthroplasty Performed by a Canadian Short-Stay Surgical Team in Ecuador Open
Background . Few charitable overseas surgical missions produce cost-effectiveness analyses of their work. Methods . We compared the pre- and postoperative health status for 157 total hip arthroplasty (THA) patients operated on from 2007 to…
View article: Comparative effectiveness of pediatric integrative medicine as an adjunct to usual care for pediatric inpatients of a North American tertiary care centre: A study protocol for a pragmatic cluster controlled trial
Comparative effectiveness of pediatric integrative medicine as an adjunct to usual care for pediatric inpatients of a North American tertiary care centre: A study protocol for a pragmatic cluster controlled trial Open
This trial will be the first to evaluate the comparative effectiveness, both clinical and cost, of a PIM inpatient service. The evidence from this study will be useful to families, clinicians and decision makers, and will describe the clin…