Michael Scolarici
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View article: Landscape of Current Transplant Infectious Disease Training Programs
Landscape of Current Transplant Infectious Disease Training Programs Open
Background Transplant infectious disease (TID) training is not accredited by the Accreditation Council for Graduate Medical Education (ACGME) and is not standardized. Prior surveys of the training landscape in TID have focused on fellow re…
View article: Research Advice for Early Career Transplant Infectious Disease Clinicians
Research Advice for Early Career Transplant Infectious Disease Clinicians Open
As part of an ongoing series of social media discussions, the Transplant Infectious Diseases Early Career Network hosted an open forum for the transplant infectious disease community to discuss the development of research careers for junio…
View article: Donor-Derived Ehrlichiosis Caused by <i>Ehrlichia chaffeensis</i> from Living Donor Kidney Transplant
Donor-Derived Ehrlichiosis Caused by <i>Ehrlichia chaffeensis</i> from Living Donor Kidney Transplant Open
Tickborne infections are challenging to diagnose, particularly among solid organ transplant recipients. We report a US case of donor-derived ehrlichiosis from a living kidney donation that highlights how screening for living donors may mis…
View article: Histoplasmosis and blastomycosis: Progress and possibilities
Histoplasmosis and blastomycosis: Progress and possibilities Open
Background: Histoplasmosis and blastomycosis are important global fungal infections that primarily start as pulmonary pathogens but can lead to disseminated, fatal disease requiring prolonged antifungal therapy. Objectives: In this narrati…
View article: P-975. Comprehensive Survey of Current Transplant Infectious Disease Fellowship Programs
P-975. Comprehensive Survey of Current Transplant Infectious Disease Fellowship Programs Open
Background Adult Transplant Infectious Disease (TID) training is not ACGME accredited, and there is heterogeneity in training offered at transplant centers. Methods The American Society of Transplantation ID Community of Practice surveyed …
View article: Infective endocarditis is rare in patients with hematologic malignancy and neutropenia
Infective endocarditis is rare in patients with hematologic malignancy and neutropenia Open
Background Infective endocarditis (IE) is a serious complication of bloodstream infections (BSIs) that occurs at variable rates depending on the pathogen and clinical setting. There is a paucity of data describing the risk of IE in patient…
View article: 2113. Infectious endocarditis in patients with hematologic malignancy at the University of Wisconsin
2113. Infectious endocarditis in patients with hematologic malignancy at the University of Wisconsin Open
Background Infective endocarditis (IE) is a highly morbid complication of blood stream infections (BSIs) involving neutrophil and platelet activation. Patients with hematologic malignancies have frequent BSIs but a low incidence of IE. We …
View article: The Role of Isavuconazonium Sulphate for the Treatment of Blastomycosis: A Case Series and Antifungal Susceptibility
The Role of Isavuconazonium Sulphate for the Treatment of Blastomycosis: A Case Series and Antifungal Susceptibility Open
Background Blastomyces spp, the etiologic agents of blastomycosis, are endemic dimorphic fungi that require prolonged antifungal therapy, which can be complicated by adverse drug effects. Isavuconazonium sulphate (ISA) is a triazole with i…
View article: 989. Isavuconazonium Sulfate Treatment of Blastomycosis: A Case Series
989. Isavuconazonium Sulfate Treatment of Blastomycosis: A Case Series Open
Background Blastomyces fungi, endemic to the Ohio and Mississippi River Valleys, cause pneumonia and disseminated disease in both immunocompetent and immunocompromised patients. Prolonged antifungal therapy is commonly complicated by hepat…
View article: Fungal Infections in Liver Transplant Recipients
Fungal Infections in Liver Transplant Recipients Open
Invasive fungal infections (IFIs) are one of the most feared complications associated with liver transplantation, with high rates of morbidity and mortality. We discuss the most common invasive fungal infections in the setting of liver tra…
A scoring strategy for progression risk and rates of treatment completion in subjects with latent tuberculosis Open
View article: Use of a scoring strategy to determine clinical risk of progression and risk group-specific treatment adherence in subjects with latent tuberculosis infection
Use of a scoring strategy to determine clinical risk of progression and risk group-specific treatment adherence in subjects with latent tuberculosis infection Open
Background Annual incidence of active tuberculosis (TB) cases has plateaued in the US from 2013-2015. Most cases are from reactivation of latent tuberculosis infection (LTBI). A likely contributor is suboptimal LTBI treatment completion ra…
View article: Using a Validated Calculator to Assess the Risk of Disease Progression and Treatment Completion in Patients with Human Immunodeficiency Virus Infection and Latent TB
Using a Validated Calculator to Assess the Risk of Disease Progression and Treatment Completion in Patients with Human Immunodeficiency Virus Infection and Latent TB Open
HIV-infection leads to a higher risk of progression from asymptomatic, non-transmissible latent tuberculosis infection (LTBI) to active tuberculosis (TB). Specific comorbid medical risk factors increase this risk which can be decreased by …
View article: Use of a Validated Online Calculator to Determine TB Progression Risk in Patients with Latent Tuberculosis Infection on TNFα Therapy
Use of a Validated Online Calculator to Determine TB Progression Risk in Patients with Latent Tuberculosis Infection on TNFα Therapy Open
Patients with latent tuberculosis infection (LTBI) on anti-TNFα therapy (TNFα group) have an increased risk of developing active tuberculosis (TB). Risk of progression can be decreased by completing prophylactic treatment; a 3-month regime…