Michael Selgrad
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View article: Prevalence of Helicobacter pylori and its Association with Extragastric Diseases in a Tertiary Hospital from East Bavaria
Prevalence of Helicobacter pylori and its Association with Extragastric Diseases in a Tertiary Hospital from East Bavaria Open
Background: Helicobacter pylori (H. pylori) infection remains a significant burden in gastroduodenal diseases. However, contemporary data on the prevalence of H. pylori infection in Germany are limited. Aim: This study aimed to evaluate th…
View article: Liver cirrhosis is a risk-factor for Pneumocystis jirovecii associated mortality
Liver cirrhosis is a risk-factor for Pneumocystis jirovecii associated mortality Open
Background Pneumocystis jirovecci pneumonia (PCP) is a life threating disease in immunodeficient patients. Liver cirrhosis itself can lead to immunodefiency, however little is known if Pneumocystis jirovecci infection affects the outcome o…
View article: Supplementary Materials from Chemoprevention of Intestinal Polyps in Apc<sup>Min/+</sup> Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract
Supplementary Materials from Chemoprevention of Intestinal Polyps in Apc<sup>Min/+</sup> Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract Open
Supplementary Materials from Chemoprevention of Intestinal Polyps in ApcMin/+ Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract
View article: Supplementary Materials from Chemoprevention of Intestinal Polyps in Apc<sup>Min/+</sup> Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract
Supplementary Materials from Chemoprevention of Intestinal Polyps in Apc<sup>Min/+</sup> Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract Open
Supplementary Materials from Chemoprevention of Intestinal Polyps in ApcMin/+ Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract
View article: Data from Chemoprevention of Intestinal Polyps in Apc<sup>Min/+</sup> Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract
Data from Chemoprevention of Intestinal Polyps in Apc<sup>Min/+</sup> Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract Open
The Western diet (WD) is associated with a higher incidence of colorectal cancer (CRC) than the Mediterranean diet. Polyphenols extracted from Annurca apple showed chemopreventive properties in CRC cells. A multifactorial, four-arm study b…
View article: Data from Chemoprevention of Intestinal Polyps in Apc<sup>Min/+</sup> Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract
Data from Chemoprevention of Intestinal Polyps in Apc<sup>Min/+</sup> Mice Fed with Western or Balanced Diets by Drinking Annurca Apple Polyphenol Extract Open
The Western diet (WD) is associated with a higher incidence of colorectal cancer (CRC) than the Mediterranean diet. Polyphenols extracted from Annurca apple showed chemopreventive properties in CRC cells. A multifactorial, four-arm study b…
View article: Supplementary Data from Highly Purified Eicosapentaenoic Acid as Free Fatty Acids Strongly Suppresses Polyps in Apc<sup>Min/+</sup> Mice
Supplementary Data from Highly Purified Eicosapentaenoic Acid as Free Fatty Acids Strongly Suppresses Polyps in Apc<sup>Min/+</sup> Mice Open
Supplementary Figures S1-S3 and Supplementary Tables S1-S3.
View article: Data from Highly Purified Eicosapentaenoic Acid as Free Fatty Acids Strongly Suppresses Polyps in Apc<sup>Min/+</sup> Mice
Data from Highly Purified Eicosapentaenoic Acid as Free Fatty Acids Strongly Suppresses Polyps in Apc<sup>Min/+</sup> Mice Open
Purpose: Although cyclooxygenase (COX)-2 inhibitors could represent the most effective chemopreventive tool against colorectal cancer (CRC), their use in clinical practice is hampered by cardiovascular side effects. Consumption of ω-3-poly…
View article: Supplementary Data from Highly Purified Eicosapentaenoic Acid as Free Fatty Acids Strongly Suppresses Polyps in Apc<sup>Min/+</sup> Mice
Supplementary Data from Highly Purified Eicosapentaenoic Acid as Free Fatty Acids Strongly Suppresses Polyps in Apc<sup>Min/+</sup> Mice Open
Supplementary Figures S1-S3 and Supplementary Tables S1-S3.
View article: Data from Highly Purified Eicosapentaenoic Acid as Free Fatty Acids Strongly Suppresses Polyps in Apc<sup>Min/+</sup> Mice
Data from Highly Purified Eicosapentaenoic Acid as Free Fatty Acids Strongly Suppresses Polyps in Apc<sup>Min/+</sup> Mice Open
Purpose: Although cyclooxygenase (COX)-2 inhibitors could represent the most effective chemopreventive tool against colorectal cancer (CRC), their use in clinical practice is hampered by cardiovascular side effects. Consumption of ω-3-poly…
View article: The influence of gastric atrophy on Helicobacter pylori antibiotics resistance in therapy-naïve patients
The influence of gastric atrophy on Helicobacter pylori antibiotics resistance in therapy-naïve patients Open
Background Antibiotic susceptibility of Helicobacter pylori to antibiotics may vary among different niches of the stomach. The progression of chronic H. pylori gastritis to atrophy changes intragastric physiology that may influence selecti…
View article: Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction
Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction Open
Cancers occurring at the gastroesophageal junction (GEJ) are classified as predominantly esophageal or gastric, which is often difficult to decipher. We hypothesized that the transcriptomic profile might reveal molecular subgroups which co…
View article: Combined Gastric and Colorectal Cancer Screening—A New Strategy
Combined Gastric and Colorectal Cancer Screening—A New Strategy Open
Background: Our aim was to evaluate the feasibility of a serological assessment of gastric cancer risk in patients undergoing colonoscopy in countries with low-to-moderate incidence rates. Methods: Serum samples were prospectively collecte…
View article: Migrants and Refugees in Europe: Challenges, Experiences and Contributions
Migrants and Refugees in Europe: Challenges, Experiences and Contributions Open
Due to the current geopolitical situation more refugees from crisis countries were and will be treated in Europe. In 2015 the number of displaced people reached an unprecedented level, with more than one million crossing into Europe. The m…
View article: Management of Helicobacter pylori Infection: What Should the Surgeon Know
Management of Helicobacter pylori Infection: What Should the Surgeon Know Open
Infection with Helicobacter pylori continues to represent a major global health care burden, and various national and international consensus reports and guidelines have aimed at tracking recent developments for their translation into an o…
View article: Management of <i>Helicobacter pylori</i> infection—the Maastricht V/Florence Consensus Report
Management of <i>Helicobacter pylori</i> infection—the Maastricht V/Florence Consensus Report Open
Important progress has been made in the management of Helicobacter pylori infection and in this fifth edition of the Maastricht Consensus Report, key aspects related to the clinical role of H. pylori were re-evaluated in 2015. In the Maast…
View article: Expression of aurora kinase A correlates with the Wnt‐modulator <scp>RACGAP</scp>1 in gastric cancer
Expression of aurora kinase A correlates with the Wnt‐modulator <span>RACGAP</span>1 in gastric cancer Open
Canonical Wnt signaling is involved in gastric carcinogenesis. The aim of this study was to identify the link between Wnt signaling and aurora kinase A ( AURKA ), a target for the treatment of gastrointestinal cancers. Publicly available m…