Michael Studnicka
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View article: ECG-based identification of COPD patients at risk for atrial fibrillation and its impact on adverse clinical outcomes—a subgroup analysis of the prospective multicenter COSYCONET cohort
ECG-based identification of COPD patients at risk for atrial fibrillation and its impact on adverse clinical outcomes—a subgroup analysis of the prospective multicenter COSYCONET cohort Open
Background Atrial fibrillation (AF) frequently occurs in patients with chronic obstructive pulmonary disease (COPD) and is associated with adverse clinical outcomes. We aimed to identify patients at risk for AF using amplified p-wave durat…
View article: Hospitalisations in patients with idiopathic pulmonary fibrosis: insights from the IPF-PRO Registry and EMPIRE Registry
Hospitalisations in patients with idiopathic pulmonary fibrosis: insights from the IPF-PRO Registry and EMPIRE Registry Open
Background We used data from the European MultiPartner IPF Registry (EMPIRE) and the US Idiopathic Pulmonary Fibrosis-PRospective Outcomes (IPF-PRO) Registry to examine the frequency of hospitalisation, risk factors associated with hospita…
View article: Supplemental Oxygen during Exercise Training in Chronic Obstructive Pulmonary Disease
Supplemental Oxygen during Exercise Training in Chronic Obstructive Pulmonary Disease Open
Introduction Chronic obstructive pulmonary disease is a leading cause of mortality worldwide and a debilitating condition that leads to years of poor quality of life. Physical exercise training is an evidence-based treatment well documente…
View article: Midregional Proatrial Natriuretic Peptide (MRproANP) is associated with vertebral fractures and low bone density in patients with chronic obstructive pulmonary disease (COPD)
Midregional Proatrial Natriuretic Peptide (MRproANP) is associated with vertebral fractures and low bone density in patients with chronic obstructive pulmonary disease (COPD) Open
View article: Statins did not reduce the frequency of exacerbations in individuals with COPD and cardiovascular comorbidities in the COSYCONET cohort
Statins did not reduce the frequency of exacerbations in individuals with COPD and cardiovascular comorbidities in the COSYCONET cohort Open
View article: Inspiratory Crackles in Idiopathic Pulmonary Fibrosis – Friend or Foe for Early Diagnosis?
Inspiratory Crackles in Idiopathic Pulmonary Fibrosis – Friend or Foe for Early Diagnosis? Open
Background: Velcro crackles (VCR) are frequent in idiopathic pulmonary fibrosis (IPF) patients and have been advocated as a tool for early diagnosis. We assessed their association with clinical features, progression, and survival in the Eu…
View article: Midregional proatrial naturetic peptide (MRproANP) and copeptin (COPAVP) as predictors of all-cause mortality in recently diagnosed mild to moderate COPD—results from COSYCONET
Midregional proatrial naturetic peptide (MRproANP) and copeptin (COPAVP) as predictors of all-cause mortality in recently diagnosed mild to moderate COPD—results from COSYCONET Open
View article: Physical Activity, Depression and Quality of Life in COPD – Results from the CLARA II Study
Physical Activity, Depression and Quality of Life in COPD – Results from the CLARA II Study Open
In Austria, nearly half of stable COPD outpatients reported symptoms of depression, which were associated with lower levels of self-reported physical activity, more pain, and respiratory symptoms. The associations were particularly strong …
View article: The Impact of Exercise Training and Supplemental Oxygen on Peripheral Muscles in Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial
The Impact of Exercise Training and Supplemental Oxygen on Peripheral Muscles in Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial Open
Objective Exercise training is a cornerstone of the treatment of chronic obstructive pulmonary disease, whereas the related interindividual heterogeneity in skeletal muscle dysfunction and adaptations are not yet fully understood. We set o…
View article: MRI Compared with Low-Dose CT for Incidental Lung Nodule Detection in COPD: A Multicenter Trial
MRI Compared with Low-Dose CT for Incidental Lung Nodule Detection in COPD: A Multicenter Trial Open
In a multicenter setting, morphofunctional MRI showed moderate sensitivity for detection of incidental pulmonary nodules in participants with COPD but high agreement with LDCT for Lung-RADS classification of nodules.Clinical trial registra…
View article: Durvalumab after Sequential High Dose Chemoradiotherapy versus Standard of Care (SoC) for Stage III NSCLC: A Bi-Centric Retrospective Comparison Focusing on Pulmonary Toxicity
Durvalumab after Sequential High Dose Chemoradiotherapy versus Standard of Care (SoC) for Stage III NSCLC: A Bi-Centric Retrospective Comparison Focusing on Pulmonary Toxicity Open
Introduction: The standard of care (SoC) for unresectable stage III non-small-cell lung cancer (NSCLC) is durvalumab maintenance therapy after concurrent chemoradiation in patients with PD-L1 > 1%. However, the concurrent approach is only …
View article: Comorbidity burden and survival in patients with idiopathic pulmonary fibrosis: the EMPIRE registry study
Comorbidity burden and survival in patients with idiopathic pulmonary fibrosis: the EMPIRE registry study Open
View article: Sex-specific associations of comorbidome and pulmorbidome with mortality in chronic obstructive pulmonary disease: results from COSYCONET
Sex-specific associations of comorbidome and pulmorbidome with mortality in chronic obstructive pulmonary disease: results from COSYCONET Open
In patients with COPD, it has not been comprehensively assessed whether the predictive value of comorbidities for mortality differs between men and women. We therefore aimed to examine sex differences of COPD comorbidities in regard with p…
View article: Carbon Monoxide Diffusing Capacity (DLCO) Correlates with CT Morphology after Chemo-Radio-Immunotherapy for Non-Small Cell Lung Cancer Stage III
Carbon Monoxide Diffusing Capacity (DLCO) Correlates with CT Morphology after Chemo-Radio-Immunotherapy for Non-Small Cell Lung Cancer Stage III Open
Introduction: Curatively intended chemo-radio-immunotherapy for non-small cell lung cancer (NSCLC) stage III may lead to post-therapeutic pulmonary function (PF) impairment. We hypothesized that the decrease in global PF corresponds to the…
View article: Reduced decline of lung diffusing capacity in COPD patients with diabetes and metformin treatment
Reduced decline of lung diffusing capacity in COPD patients with diabetes and metformin treatment Open
View article: High Dose Thoracic Re-Irradiation and Chemo-Immunotherapy for Centrally Recurrent NSCLC
High Dose Thoracic Re-Irradiation and Chemo-Immunotherapy for Centrally Recurrent NSCLC Open
Introduction: Thoracic re-irradiation for recurrent lung cancer dates back four decades, when the first small series on 29 patients receiving palliative doses was published. With 5-year overall survival rates of 57% in PDL-1 positive patie…
View article: Real-world experience with capmatinib in <i>MET</i> exon 14-mutated non-small cell lung cancer (RECAP): a retrospective analysis from an early access program
Real-world experience with capmatinib in <i>MET</i> exon 14-mutated non-small cell lung cancer (RECAP): a retrospective analysis from an early access program Open
Background: Patients with non-small cell lung cancer (NSCLC) presenting with mesenchymal–epithelial transition ( MET) exon 14 skipping mutation have an unfavorable prognosis with standard treatments. Capmatinib is a selective MET inhibitor…
View article: Re-Irradiation for Locally Recurrent Lung Cancer: A Single Center Retrospective Analysis
Re-Irradiation for Locally Recurrent Lung Cancer: A Single Center Retrospective Analysis Open
The treatment of locally recurrent lung cancer is a major challenge for radiation-oncologists, especially with data on high-dose reirradiation being limited to small retrospective studies. The aim of the present study is to assess overall …
View article: Impact of reirradiation, chemotherapy, and immunotherapy on survival of patients with recurrent lung cancer: A single‐center retrospective analysis
Impact of reirradiation, chemotherapy, and immunotherapy on survival of patients with recurrent lung cancer: A single‐center retrospective analysis Open
Background Given the limited curative treatment options for recurrent lung cancer patients, the aim of our retrospective study was to investigate whether these patients would benefit in terms of overall survival (OS) by adding immunotherap…
View article: The Leukotriene Receptor Antagonist Montelukast as a Potential COVID-19 Therapeutic
The Leukotriene Receptor Antagonist Montelukast as a Potential COVID-19 Therapeutic Open
The emergence and global impact of COVID-19 has focused the scientific and medical community on the pivotal influential role of respiratory viruses as causes of severe pneumonia, on the understanding of the underlying pathomechanisms, and …
View article: Leitlinie zur Langzeit-Sauerstofftherapie
Leitlinie zur Langzeit-Sauerstofftherapie Open
Zusammenfassung Die Langzeit-Sauerstofftherapie hat einen hohen Stellenwert sowohl zur Verminderung der Letalität als auch zur Verbesserung der Leistungsfähigkeit bei Patienten mit chronischen Lungenerkrankungen. Die Grundvoraussetzung für…
View article: Impact of exercise training and supplemental oxygen on submaximal exercise performance in patients with COPD
Impact of exercise training and supplemental oxygen on submaximal exercise performance in patients with COPD Open
Functional impairment caused by chronic obstructive pulmonary disease (COPD) impacts on activities of daily living and quality of life. Indeed, patients’ submaximal exercise capacity is of crucial importance. It was the aim of this study t…
View article: <p>Impact of Education on COPD Severity and All-Cause Mortality in Lifetime Never-Smokers and Longtime Ex-Smokers: Results of the COSYCONET Cohort</p>
Impact of Education on COPD Severity and All-Cause Mortality in Lifetime Never-Smokers and Longtime Ex-Smokers: Results of the COSYCONET Cohort Open
Overall, in the COSYCONET COPD cohort, differences in functional status between never-smokers and long-time ex-smokers were not large. Compared to that, the dependence on education level was more prominent, with higher education associated…
View article: Impact of Education on COPD Severity and All-Cause Mortality in Lifetime Never-Smokers and Longtime Ex-Smokers: Results of the COSYCONET Cohort
Impact of Education on COPD Severity and All-Cause Mortality in Lifetime Never-Smokers and Longtime Ex-Smokers: Results of the COSYCONET Cohort Open
Johanna I Lutter,1 Rudolf A Jörres,2 Tobias Welte,3 Henrik Watz,4 Benjamin Waschki,5 Peter Alter,6 Franziska C Trudzinski,7 Johan Ohlander,1,8 Jürgen Behr,9 Robert Bals,10 Michael Studnicka,11 Rolf Holle,12 Claus F Vogelmeier,6 Kathrin Kah…
View article: Masterplan 2025 der Österreichischen Gesellschaft für Pneumologie (ÖGP) – die erwartete Entwicklung und Versorgung respiratorischer Erkrankungen in Österreich
Masterplan 2025 der Österreichischen Gesellschaft für Pneumologie (ÖGP) – die erwartete Entwicklung und Versorgung respiratorischer Erkrankungen in Österreich Open
Zusammenfassung Mitglieder der Österreichischen Gesellschaft für Pneumologie (ÖGP) beschreiben die erwartete Entwicklung der respiratorischen Gesundheit und zeigen Wege einer patientenorientierten und kosteneffizienten Versorgung für Öster…
View article: Utilization and determinants of use of non-pharmacological interventions in COPD: Results of the COSYCONET cohort
Utilization and determinants of use of non-pharmacological interventions in COPD: Results of the COSYCONET cohort Open
View article: <p>Quality of Life and Limitations in Daily Life of Stable COPD Outpatients in a Real-World Setting in Austria – Results from the CLARA Project</p>
Quality of Life and Limitations in Daily Life of Stable COPD Outpatients in a Real-World Setting in Austria – Results from the CLARA Project Open
In Austria, the burden of disease in COPD outpatients tends to be underestimated in patients with milder airway obstruction and less exacerbations and overestimated in patients with more severe airway obstruction and frequent exacerbations…
View article: Associations of oxygenated hemoglobin with disease burden and prognosis in stable COPD: Results from COSYCONET
Associations of oxygenated hemoglobin with disease burden and prognosis in stable COPD: Results from COSYCONET Open
View article: Health-related quality of life associates with change in FEV1 in COPD: results from the COSYCONET cohort
Health-related quality of life associates with change in FEV1 in COPD: results from the COSYCONET cohort Open
Background Forced expiratory volume in one second (FEV 1 ) characterizes the pathophysiology of COPD and different trajectories of FEV 1 decline have been observed in patients with COPD (e.g. gradual or episodic). There is limited informat…
View article: Blood eosinophil count in the general population: typical values and potential confounders
Blood eosinophil count in the general population: typical values and potential confounders Open
There is growing interest in blood eosinophil counts in the management of chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Despite this, typical blood eosinophil levels in the general populati…