Michael Tee
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Author Swipe
View article: Predictors of damage accrual by organ domain in systemic lupus erythematosus
Predictors of damage accrual by organ domain in systemic lupus erythematosus Open
Objectives Organ damage in systemic lupus erythematosus (SLE) is assessed using the SLICC/ACR Damage Index (SDI), which quantifies damage in 12 organ systems but generally reports a total score. We examined whether the risk factors for ove…
View article: Prevalence, determinants and outcomes of low disease activity and remission attainment in <scp>SLE</scp> patients with clinically active disease
Prevalence, determinants and outcomes of low disease activity and remission attainment in <span>SLE</span> patients with clinically active disease Open
Objectives This study aimed to identify the frequency and determinants of Lupus Low Disease Activity State (LLDAS) and Definition of Remission in SLE (DORIS‐remission) attainment in systemic lupus erythematosus (SLE) patients with clinical…
View article: Informing trial measurement in systemic lupus erythematosus: frequency of domain-specific disease activity in a multinational cohort
Informing trial measurement in systemic lupus erythematosus: frequency of domain-specific disease activity in a multinational cohort Open
Objective To report the prevalence of disease activity in individual SLE organ domains, including prevalence stratified by the most common disease activity cut-off score for clinical trial eligibility (SLE Disease Activity Index 2000; SLED…
View article: SEX DIFFERENCES IN SYSTEMIC LUPUS ERYTHEMATOSUS: A COMPREHENSIVE ANALYSIS OF CLINICAL AND TREATMENT DISPARATIES IN A MULTICENTER LONGITUDINAL COHORT
SEX DIFFERENCES IN SYSTEMIC LUPUS ERYTHEMATOSUS: A COMPREHENSIVE ANALYSIS OF CLINICAL AND TREATMENT DISPARATIES IN A MULTICENTER LONGITUDINAL COHORT Open
PV190 / #379 Poster Topic: AS22 - SLE Heterogeneity Background/Purpose Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with female predominance. Due to its lower prevalence in men, SLE is less well understood in male pat…
View article: DEMOGRAPHIC AND CLINICAL CHARACTERISTICS OF PATIENTS WITH SLE ACROSS 5 REGISTRIES – THE LUPUSNET FEDERATED DATA NETWORK
DEMOGRAPHIC AND CLINICAL CHARACTERISTICS OF PATIENTS WITH SLE ACROSS 5 REGISTRIES – THE LUPUSNET FEDERATED DATA NETWORK Open
PV193 / #375 Poster Topic: AS22 - SLE Heterogeneity Background/Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease with a broad range of clinical manifestations and a high unmet need across patient populations. Real-world d…
View article: Assessing hand grip strength as a nutritional indicator in hemodialysis patients: reliability and agreement between pre-dialysis and mid-dialysis measurements
Assessing hand grip strength as a nutritional indicator in hemodialysis patients: reliability and agreement between pre-dialysis and mid-dialysis measurements Open
Handgrip strength (HGS) is a marker of protein-energy status in people on haemodialysis (HD). Best practice guidelines recommend measuring HGS before the commencement of the dialysis session, which is not always possible (1) . No previous …
View article: Frequency and Determinants of Flare and Persistently Active Disease in a Large Multinational Prospective Lupus Cohort
Frequency and Determinants of Flare and Persistently Active Disease in a Large Multinational Prospective Lupus Cohort Open
Objective In contrast to relapsing‐remitting patterns, persistently active disease (PAD) is a disease activity pattern in patients with systemic lupus erythematosus (SLE) that is inadequately studied. We sought to identify the frequency an…
View article: Time trends of variability in disease activity in systemic lupus erythematosus
Time trends of variability in disease activity in systemic lupus erythematosus Open
Objective Disease activity both between and within patients with SLE is highly variable, yet factors driving this variability remain unclear. This study aimed to identify predictors of variability in SLE disease activity over time. Methods…
View article: Association of lupus low disease activity state and remission with reduced organ damage and flare in systemic lupus erythematosus patients with high disease activity: a multi-national, longitudinal cohort study
Association of lupus low disease activity state and remission with reduced organ damage and flare in systemic lupus erythematosus patients with high disease activity: a multi-national, longitudinal cohort study Open
Objective High disease activity status (HDAS) in patients with systemic lupus erythematosus (SLE) is associated with adverse long-term outcomes. We examined the frequency of lupus low disease activity state (LLDAS) and remission (REM) atta…
View article: Sub-optimal use of anti-malarial therapy for SLE in the Asia Pacific region: observations from the Asia Pacific lupus cohort
Sub-optimal use of anti-malarial therapy for SLE in the Asia Pacific region: observations from the Asia Pacific lupus cohort Open
Introduction The guidelines for management of patients with systemic lupus erythematosus (SLE) recommend the use of anti-malarial (AM) drugs [commonly hydroxychloroquine (HCQ)] in all patients, unless contraindicated. We evaluated the prev…
View article: Developing an immersive gamification technology system for the management of patients with behavioral and psychological symptoms of dementia (Phase 1 trial)
Developing an immersive gamification technology system for the management of patients with behavioral and psychological symptoms of dementia (Phase 1 trial) Open
Background Virtual reality (VR) technology has been increasingly used in the management of people living with dementia, serving as a novel and important non‐pharmacologic approach to address the complex behavioral and psychological symptom…
View article: Association Between 25-hydroxyvitamin D Levels and Testosterone in Healthy, Non-Obese, Young Adult, Filipino Men
Association Between 25-hydroxyvitamin D Levels and Testosterone in Healthy, Non-Obese, Young Adult, Filipino Men Open
There is no association between vitamin D and TT, FT nor SHBG in our cohort with deficient vitamin D levels.
View article: LSO-080 Machine-learning approach on lupus low disease activity prediction
LSO-080 Machine-learning approach on lupus low disease activity prediction Open
Background The development of lupus low disease activity state (LLDAS) as a treat-to-target endpoint for SLE patients has been validated. Its attainment has been associated with improved outcomes. This study aims to show whether a machine …
View article: LSO-087 Sub-optimal use of anti-malarial therapy for SLE in the Asia Pacific region; observations from the Asia Pacific lupus cohort
LSO-087 Sub-optimal use of anti-malarial therapy for SLE in the Asia Pacific region; observations from the Asia Pacific lupus cohort Open
Background The Asia-Pacific League of Associations for Rheumatology (APLAR) recently published consensus recommendations, including overarching principles, general management, and specific treatment strategies for SLE in Asia. The use of h…
View article: LSO-031 Association of serologic and clinical low disease activity states with outcomes in a large multi-national lupus cohort
LSO-031 Association of serologic and clinical low disease activity states with outcomes in a large multi-national lupus cohort Open
Background Lupus Low Disease Activity State (LLDAS) permits serological activity and activity in several organs including joint, muscle, and mucocutaneous activity, provided SLEDA4-2K is <=4 and other LLDAS criteria are met. Methods Patien…
View article: LO-004 Frequency and determinants of flare and persistently active disease in a large multinational prospective lupus cohort
LO-004 Frequency and determinants of flare and persistently active disease in a large multinational prospective lupus cohort Open
Background The current commonly used definitions of flare may not be able to capture patients with a persistently active disease (PAD) course. This study sought to identity the frequency and determinants of flare and PAD in an Asia-Pacific…
View article: OP0226 ATTAINMENT OF LUPUS LOW DISEASE ACTIVITY STATE EXCLUSIVE OF REMISSION IS PROTECTIVE AGAINST ADVERSE OUTCOMES IN SYSTEMIC LUPUS ERYTHEMATOSUS
OP0226 ATTAINMENT OF LUPUS LOW DISEASE ACTIVITY STATE EXCLUSIVE OF REMISSION IS PROTECTIVE AGAINST ADVERSE OUTCOMES IN SYSTEMIC LUPUS ERYTHEMATOSUS Open
View article: SMART-SLE: serology monitoring and repeat testing in systemic lupus erythematosus—an analysis of anti-double-stranded DNA monitoring
SMART-SLE: serology monitoring and repeat testing in systemic lupus erythematosus—an analysis of anti-double-stranded DNA monitoring Open
Objective Disease activity monitoring in SLE includes serial measurement of anti-double stranded-DNA (dsDNA) antibodies, but in patients who are persistently anti-dsDNA positive, the utility of repeated measurement is unclear. We investiga…
View article: Awareness, knowledge, attitude, and practices (A-KAP) assessment of the One Health approach in health sciences education webinar series participants in select universities in the Philippines
Awareness, knowledge, attitude, and practices (A-KAP) assessment of the One Health approach in health sciences education webinar series participants in select universities in the Philippines Open
Background A three-day One Health training program for undergraduate and graduate students, as well as professionals in One Health-related fields, was conducted by the Philippine One Health University Network (PhilOHUN), in collaboration w…
View article: Abstracts
Abstracts Open
Aims: Aberrant immune cell activation characterises SLE, in which glucocorticoids (GCs) remain a cornerstone of treatment.However, the unacceptable side effects of GCs have created a pressing need for a similarly broad-acting, but safer, a…
View article: Are There Differences between the Stress Responses of Philippine Men and Women to the COVID-19 Pandemic?
Are There Differences between the Stress Responses of Philippine Men and Women to the COVID-19 Pandemic? Open
The SARS-CoV-2 pandemic has had a deleterious impact on human health since its beginning in 2019. The purpose of this study was to examine the psychosocial impact of the COVID-19 pandemic in the Philippines and determine if there were diff…
View article: Intravenous Tocilizumab versus Standard of Care in the Treatment of Severe and Critical COVID-19-related Pneumonia: A Single Center, Double-blind, Placebo Controlled, Phase 3 Trial
Intravenous Tocilizumab versus Standard of Care in the Treatment of Severe and Critical COVID-19-related Pneumonia: A Single Center, Double-blind, Placebo Controlled, Phase 3 Trial Open
The use of tocilizumab on top of standard of care in the management of patients with severe to critical COVID-19 did not result in significant improvement as defined by the WHO 7-point Ordinal Scale of patient status, nor in significant im…
View article: To Vaccinate or Not to Vaccinate—Reasons of Willingness and Reluctance of Students against SARS-CoV-2 Vaccination—An International Experience
To Vaccinate or Not to Vaccinate—Reasons of Willingness and Reluctance of Students against SARS-CoV-2 Vaccination—An International Experience Open
Despite the vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) being reported to be safe and effective, the unwillingness to vaccinate and doubts are still common. The aim of this international study was to as…
View article: Association of Modified Systemic Lupus Erythematosus Responder Index Attainment With <scp>Long‐Term</scp> Clinical Outcomes: A <scp>Five‐Year</scp> Prospective Study
Association of Modified Systemic Lupus Erythematosus Responder Index Attainment With <span>Long‐Term</span> Clinical Outcomes: A <span>Five‐Year</span> Prospective Study Open
Objective In trials of systemic lupus erythematosus (SLE), the SLE Responder Index (SRI) is the most commonly used primary efficacy end point but has limited validation against long‐term outcomes. We aimed to investigate associations of at…
View article: Physician Global Assessment International Standardisation COnsensus in Systemic Lupus Erythematosus: the PISCOS study
Physician Global Assessment International Standardisation COnsensus in Systemic Lupus Erythematosus: the PISCOS study Open
View article: A community-based survey to assess risk for one health challenges in rural Philippines using a mobile application
A community-based survey to assess risk for one health challenges in rural Philippines using a mobile application Open
View article: Clinical Profile of Filipino Patients with Young-onset Gout
Clinical Profile of Filipino Patients with Young-onset Gout Open
Objectives. Recent studies show that patients with young-onset gout present with visible tophi or nephrolithiasis on diagnosis. In the Philippines, where gout is prevalent, there is no published work on this subset of patients. This study …
View article: Single nucleotide polymorphism (SNP) in genes of lupus: A Philippine study (SIGLA‐PH)
Single nucleotide polymorphism (SNP) in genes of lupus: A Philippine study (SIGLA‐PH) Open
Background Systemic lupus erythematosus (SLE) is a complex prototypic autoimmune disease, with a prevalence of 20–150 per 100,000, most commonly affecting women at child‐bearing age. Genome‐wide association studies and fine mapping of cand…
View article: A chain mediation model on COVID-19 symptoms and mental health outcomes in Americans, Asians and Europeans
A chain mediation model on COVID-19 symptoms and mental health outcomes in Americans, Asians and Europeans Open
The novel Coronavirus-2019 (COVID-19) was declared a pandemic by the World Health Organization (WHO) in March 2020, impacting the lifestyles, economy, physical and mental health of individuals globally. This study aimed to test the model t…
View article: Self-Reported Symptoms in a Cohort of Rheumatoid Arthritis and Systemic Lupus Erythematosus during the COVID-19 Quarantine Period
Self-Reported Symptoms in a Cohort of Rheumatoid Arthritis and Systemic Lupus Erythematosus during the COVID-19 Quarantine Period Open
Background: During the first three months of the COVID-19 pandemic in the Philippines, there was a supply shortage of hydroxychloroquine and methotrexate. Limited access to medication and the life changes resulting from the COVID-19 pandem…