Michael Treiber
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View article: Predictors of treatment response to adjunctive vagus nerve stimulation in difficult-to-treat depression: a retrospective data analysis
Predictors of treatment response to adjunctive vagus nerve stimulation in difficult-to-treat depression: a retrospective data analysis Open
Background Difficult-to-treat-Depression (DTD) is a highly prevalent and burdening mental illness. Approximately 25% of patients are considered as treatment-refractory. Vagus nerve stimulation (VNS) has been suggested a promising add-on tr…
View article: Neurological Soft Signs and Thyroid Hormones in Schizophrenia
Neurological Soft Signs and Thyroid Hormones in Schizophrenia Open
Introduction Neurological soft signs (NSS) are subtle sensory and motor deficits linked to neurodevelopmental disorders, schizophrenia, and thyroid disorders (TH). TH are essential for neurodevelopment and the modulation of the proinflamma…
View article: Neurological soft signs and thyroid hormones in schizophrenia spectrum disorders
Neurological soft signs and thyroid hormones in schizophrenia spectrum disorders Open
Lower fT4 levels were associated with NSS severity and specific NSS subdomains only in male individuals. In the overall sample, we detected a significant negative correlation between fT3 and negative symptoms. Future studies should examine…
View article: Titration of vagus nerve stimulation for difficult-to-treat depression and onset of response: Early insights from the RESTORE-LIFE study
Titration of vagus nerve stimulation for difficult-to-treat depression and onset of response: Early insights from the RESTORE-LIFE study Open
The majority of patients reached a current output of at least 1.5 mA, which is considered to be well within the therapeutic range. The daily charge delivered was higher in non-responders, possibly because physicians tended to increase the …
View article: Pharmacological Treatments of Negative Symptoms in Schizophrenia—An Update
Pharmacological Treatments of Negative Symptoms in Schizophrenia—An Update Open
Schizophrenia is a chronic psychotic disorder comprising positive symptoms, negative symptoms, and cognitive deficits. Negative symptoms are associated with stigma, worse functional outcomes, and a significant deterioration in quality of l…
View article: Pupillary response to percutaneous auricular vagus nerve stimulation in alcohol withdrawal syndrome: A pilot trial
Pupillary response to percutaneous auricular vagus nerve stimulation in alcohol withdrawal syndrome: A pilot trial Open
Our study suggests that pVNS activates the parasympathetic nervous system in patients with acute AWS, and that this activation is measurable by pupillometry. To this end, pVNS could be beneficial as a supportive therapy for AWS. Potential …
View article: Case report: Hyperactive delirium after a single dose of zolpidem administered additionally to psychopharmacotherapy including clozapine
Case report: Hyperactive delirium after a single dose of zolpidem administered additionally to psychopharmacotherapy including clozapine Open
The non-benzodiazepine hypnotic zolpidem is frequently administered as a short term psychopharmacotherapy for insomnia. Although it is well-established in a broad clinical routine and often well-tolerated, severe delirium and complex sleep…
View article: Case report: Interstitial pneumonitis after initiation of lamotrigine
Case report: Interstitial pneumonitis after initiation of lamotrigine Open
The second-generation anticonvulsant lamotrigine is widely used in the psychiatric field as a mood stabilizer or antidepressant augmentation therapy. Although particularly older anticonvulsants are known for their potential to cause hypers…
View article: Online Videos as a Source of Physiotherapy Exercise Tutorials for Patients with Lumbar Disc Herniation—A Quality Assessment
Online Videos as a Source of Physiotherapy Exercise Tutorials for Patients with Lumbar Disc Herniation—A Quality Assessment Open
Background: During the last few decades the prevalence of lumbar disc herniation has been increasing constantly, thereby imposing a significant socioeconomic burden. Physiotherapy plays a crucial role in both surgical and conservative trea…