Michael Velec
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View article: Reirradiation clinical practice in gastrointestinal abdominal malignancies: an international reirradiation collaborative group (ReCOG) systematic review
Reirradiation clinical practice in gastrointestinal abdominal malignancies: an international reirradiation collaborative group (ReCOG) systematic review Open
Reirradiation in abdominal malignancies appears to be able to achieve meaningful local control and survival in select patients, though heterogeneity in planning, dosing, and toxicity reporting remains a major challenge for establishing bes…
View article: Reirradiation practices of Radiation Therapists (RePoRT) study
Reirradiation practices of Radiation Therapists (RePoRT) study Open
RTT reported frequent and significant involvement in all steps of the reirradiation care pathway. Providing focused education and training for RTTs on reirradiation, coupled with team workflow optimization may enable more effective, safe a…
View article: Survey of radiation therapists’ current practices and perceptions of psychosocial and supportive care in Canada and Norway
Survey of radiation therapists’ current practices and perceptions of psychosocial and supportive care in Canada and Norway Open
Purpose Many cancer patients undergoing radiation therapy report unmet psychosocial needs, which can negatively impact their treatment outcomes and quality of life. This study explored the current practices and perceptions of radiation the…
View article: Patient-Reported Quality-of-Life Outcomes After Abdominopelvic Stereotactic Body Radiation Therapy Using an MR-Linac System
Patient-Reported Quality-of-Life Outcomes After Abdominopelvic Stereotactic Body Radiation Therapy Using an MR-Linac System Open
Stereotactic radiation treatments using online adaptive MR guided radiation therapy on MRL are well tolerated in patients with abdominopelvic metastases, with HRQoL returning to baseline at 12 months.
View article: Development and validation of an MR-driven dose-of-the-day procedure for online adaptive radiotherapy in upper gastrointestinal cancer patients
Development and validation of an MR-driven dose-of-the-day procedure for online adaptive radiotherapy in upper gastrointestinal cancer patients Open
Objective. To develop and validate a dose-of-the-day (DOTD) treatment plan verification procedure for liver and pancreas cancer patients treated with an magnetic resonance (MR)-Linac system. Approach. DOTD was implemented as an automated p…
View article: MRI evaluation of normal tissue deformation and breathing motion under an abdominal compression device
MRI evaluation of normal tissue deformation and breathing motion under an abdominal compression device Open
Purpose Abdominal compression can minimize breathing motion in stereotactic radiotherapy, though it may impact the positioning of dose‐limiting normal tissues. This study quantified the reproducibility of abdominal normal tissues and respi…
View article: Simulated daily plan adaptation for magnetic resonance-guided liver stereotactic body radiotherapy
Simulated daily plan adaptation for magnetic resonance-guided liver stereotactic body radiotherapy Open
MR-guided daily plan adaptation ensured OAR dose constraints were met at all simulated treatment fractions while CBCT-based IGRT resulted in a systematic over-dosing of OARs in patients whose doses were limited by OAR dose at the time of r…
View article: A simulation study to assess the potential impact of developing normal tissue complication probability models with accumulated dose
A simulation study to assess the potential impact of developing normal tissue complication probability models with accumulated dose Open
Assuming that accumulated dose is a more accurate representation of the true delivered dose than the planned dose, this simulation study indicates the need for prospective clinical trials to evaluate the impact of building NTCP models on t…
View article: Validation of biomechanical deformable image registration in the abdomen, thorax, and pelvis in a commercial radiotherapy treatment planning system
Validation of biomechanical deformable image registration in the abdomen, thorax, and pelvis in a commercial radiotherapy treatment planning system Open
Accuracy of biomechanical deformable registration evaluated on a large cohort of images in the thorax, abdomen and prostate was similar to the image voxel resolution on average across multiple modalities. Validation of this treatment plann…