Michael Wasney
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View article: Uniform bacterial genetic diversity along the guts of mice inoculated with human stool
Uniform bacterial genetic diversity along the guts of mice inoculated with human stool Open
Environmental gradients exist throughout the digestive tract, driving spatial variation in the membership and abundance of bacterial species along the gut. However, less is known about the distribution of genetic diversity within bacterial…
View article: Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation
Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation Open
Genome-wide association studies (GWAS) have linked hundreds of loci to cardiac diseases. However, in most loci the causal variants and their target genes remain unknown. We developed a combined experimental and analytical approach that int…
View article: Single-cell genomics improves the discovery of risk variants and genes of Atrial Fibrillation
Single-cell genomics improves the discovery of risk variants and genes of Atrial Fibrillation Open
Genome-wide association studies (GWAS) have linked hundreds of loci to cardiac diseases. However, in most loci the causal variants and their target genes remain unknown. We developed a combined experimental and analytical approach that int…
View article: Multiplexed scNOMe-seq protocol based on isolated single nuclei v3
Multiplexed scNOMe-seq protocol based on isolated single nuclei v3 Open
What follows is the protocol for performing single-cell Nucleosome Occupancy and Methylome sequencing on single nuclei (scNOMe-seq). This plate-based method, which can be used to simultaneously assess nucleosome occupancy and DNA methylati…
View article: Multiplexed scNOMe-seq protocol based on isolated single nuclei v2
Multiplexed scNOMe-seq protocol based on isolated single nuclei v2 Open
What follows is the protocol for performing single-cell Nucleosome Occupancy and Methylome sequencing on single nuclei (scNOMe-seq). This plate-based method, which can be used to simultaneously assess nucleosome occupancy and DNA methylati…
View article: Multiplexed scNOMe-seq protocol based on isolated single nuclei v1
Multiplexed scNOMe-seq protocol based on isolated single nuclei v1 Open
What follows is the protocol for performing single cell Nucleosome Occupancy and Methylome sequencing on single nuclei (scNOMe-seq). This plate-based method, which can be used to simultaneously assess nucleosome occupancy and DNA methylati…